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ORIGINAL RESEARCH article

Front. Endocrinol.

Sec. Thyroid Endocrinology

Volume 16 - 2025 | doi: 10.3389/fendo.2025.1621481

The efficacy of gasless endoscopic thyroidectomy via trans-subclavian approach in unilateral papillary thyroid carcinoma

Provisionally accepted
Xiangdang  YinXiangdang Yin1,2Jingyao  FuJingyao Fu2Zhe  ZhangZhe Zhang2Rui  ZhangRui Zhang2Zhaojun  LiZhaojun Li2Liyou  SongLiyou Song2Tong  JinTong Jin2Xudong  WangXudong Wang1*
  • 1Tianjin Medical University Cancer Institute and Hospital, Tianjin, China
  • 2Jilin Cancer Hospital, Changchun, China

The final, formatted version of the article will be published soon.

Objective: To evaluate the efficacy of gasless endoscopic thyroidectomy via the transsubclavian approach in treating unilateral papillary thyroid carcinoma. Methods: A retrospective analysis was conducted on 140 patients who underwent surgical treatment for unilateral papillary thyroid carcinoma at the Department of Oral-Maxillofacial-Thyroid Oncosurgery, Jilin Cancer Hospital, between February 2023 and August 2024. Patients were divided into the endoscopic ( n=70) and open surgery group (n=70). Clinical characteristics, surgical indicators (operation time, number of central lymph node dissections, intraoperative blood loss, 24-hour postoperative drainage volume, indwelling time of drainage tube, surgical cost, length of hospital stay), complication rates, neck discomfort, and incision satisfaction were compared. Results: Patients in the endoscopic group were younger and had a higher proportion of women (p<0.05). The endoscopic group showed significantly longer operation times and higher 24-hour drainage volumes (p<0.05). No substantial differences were observed between groups in intraoperative blood loss, lymph node dissection count, drainage tube retention time, length of hospital stay, surgical cost, and postoperative complication rates (p>0.05). Neck discomfort was considerably lower, and incision satisfaction was significantly higher in the endoscopic group (p < 0.05). Conclusion: Gasless endoscopic thyroidectomy via the trans-subclavian approach is a safe and effective treatment for unilateral papillary thyroid carcinoma.It reduces postoperative neck discomfort and improves cosmetic outcomes, making it a viable and promotable surgical option.

Keywords: Endoscopy, Trans-subclavian approach, Papillary thyroid carcinoma, feasibility, Safety

Received: 01 May 2025; Accepted: 07 Aug 2025.

Copyright: © 2025 Yin, Fu, Zhang, Zhang, Li, Song, Jin and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Xudong Wang, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China

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