EDITORIAL article
Front. Endocrinol.
Sec. Clinical Diabetes
Volume 16 - 2025 | doi: 10.3389/fendo.2025.1629375
This article is part of the Research TopicSexual Function and Dysfunction in Men and Women with DiabetesView all 6 articles
Sexual dysfunction in men and women with diabetes: what's new?
Provisionally accepted
- 1Istituto Clinico Beato Matteo, Vigevano, Italy
- 22. Department of Advanced Medical and Surgical Sciences University of Campania Luigi Vanvitelli, Naples, Italy
- 3University of Milan, Milan, Italy
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Sexual dysfunctions are frequent in men and women with diabetes [1]. Erectile dysfunction (ED) is a 8 common and debilitating complication of diabetes mellitus (DM) affecting up to 75% of men with long-9standing disease [2,3]. The pathophysiology of ED in diabetes is multifactorial, involving endothelial 10 dysfunction, neuropathy, hormonal imbalances, and psychological stressors [2,3]. Recent evidence 11 has broadened the understanding of the intricate mechanisms behind ED, as well as its clinical 12 implications and potential management strategies [2,3]. Glycaemic control, insulin resistance, 13 hypogonadism, obesity, oxidative stress, adipokine imbalance, and inflammation, often present in 14 diabetic patients, synergistically contribute to endothelial damage and compromised penile vascular 15 flow [1,2,4]. The same risk factors responsible for ED lead to early atherothrombosis [4]. In fact, one of 16 the most clinically significant associations highlighted in recent years is the link between ED and 17 cardiovascular disease [4]. Several studies suggest that ED may be an early marker of systemic 18 atherosclerosis and future cardiovascular events in diabetic men [4] The studies presented in this special issue collectively advance our understanding of the complex 70 interplay between diabetes and sexual dysfunction in men and women. They emphasize the 71 multifactorial nature of ED, the significance of personalized medicine, and the need for comprehensive 72 management strategies that address metabolic, hormonal, and psychological aspects.
Keywords: Sexual dysfuction, erectile dynsfunction, diabetes, Female Sexual Dysfunction (FSD), cardiovascular risk
Received: 15 May 2025; Accepted: 16 May 2025.
Copyright: © 2025 COPPOLA, Esposito and Gazzaruso. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Carmine Gazzaruso, University of Milan, Milan, Italy
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.