ORIGINAL RESEARCH article
Front. Endocrinol.
Sec. Diabetes: Molecular Mechanisms
Volume 16 - 2025 | doi: 10.3389/fendo.2025.1643999
This article is part of the Research TopicWorld Diabetes Day 2024: Exploring Mechanisms, Innovations, and Holistic Approaches in Diabetes CareView all 15 articles
African regional and national burden of diabetes mellitus and its attributable risk factors from 1990 to 2021:Results from the Global Burden of Disease study 2021
Provisionally accepted
Yun Qiu Wang1,2
Emmanuel Mensah3
Chao zhi Li3
De guo Wang2Wei cui Zhang2Bruno Miezah Baako4Lei Zha3
Xiang Kong2*- 1First Affiliated Hospital of Wannan Medical College, Wuhu, China
- 2Department of Gerontology, wuhu, China
- 3Department of Respiratory Medicine, wuhu, China
- 4Department of Internal Medicine, Takoradi, Ghana
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Aims: Diabetes mellitus (DM), a chronic disease characterized by hyperglycemia, has become a global health concern. This study evaluates the burden of DM in the African region from 1990-2021 to inform prevention and control strategies.Methods: Utilizing data from the Global Burden of Disease (GBD) 2021, we analyzed the incidence, prevalence, mortality, disability-adjusted life years, age-standardized rates and estimated annual percentage changes of DM, type 1 DM (T1DM) and type 2 DM (T2DM) in the African region. Decomposition analysis was utilized to explore the contributions of population growth, aging and epidemiological changes to the disease burden. The comparative risk assessment framework was employed to estimate the influence of second-level risk factors on the diabetes burden.Results ： From 1990 to 2021, the disease burden of DM, T1DM and T2DM in the African region increased significantly. The age-standardized incidence rate of DM,
Keywords: Diabetes Mellitus, disease burden, African region, Global burden of disease, public health interventions
Received: 09 Jun 2025; Accepted: 06 Aug 2025.
Copyright: © 2025 Wang, Mensah, Li, Wang, Zhang, Baako, Zha and Kong. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Xiang Kong, Department of Gerontology, wuhu, China
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