EDITORIAL article
Front. Endocrinol.
Sec. Diabetes: Molecular Mechanisms
Volume 16 - 2025 | doi: 10.3389/fendo.2025.1650648
This article is part of the Research TopicDiabetic Wound: Multifaceted Mechanisms and Future of Diabetic Wound Healing, Volume IIView all 7 articles
Editorial: Diabetic Wound: Multifaceted Mechanisms and Future of Diabetic Wound Healing, Volume II
Provisionally accepted
- 1Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- 2West China Hospital of Sichuan University, Chengdu, China
- 3National University Hospital, Singapore, Singapore
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Diabetic foot ulcer (DFU) represents a severe complication of diabetes, which will develop in an estimated 15%-25% of diabetic patients globally during their lifetime 1 .DFU is associated with significant disability and mortality rates, with reported annual mortality rate of 11% and mortality rate among those who undergo amputation surgery exceeding 22% 2 . The management of DFU continues to pose substantial clinical challenges. Six recent studies published in "Diabetic Wound: Multifaceted Mechanisms and Future of Diabetic Wound Healing, Volume II" shed light on innovative therapeutic strategies that may help to transform patient outcomes.Mesenchymal stem cells (MSCs) have been recently widely investigated in the field of wound management due to their powerful regenerative capabilities and immunomodulatory properties 3,4
Keywords: Mesenchymal Stem Cells, non-coding RNAs, Diabetic foot infection, Diabetic foot ulcer, Fibrous proteins, machine learning, transtibial transport
Received: 20 Jun 2025; Accepted: 30 Jun 2025.
Copyright: © 2025 Shao, Ran and Boey. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Xingwu Ran, West China Hospital of Sichuan University, Chengdu, China
Johnson Boey, National University Hospital, Singapore, Singapore
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