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EDITORIAL article

Front. Endocrinol.

Sec. Neuroendocrine Science

Volume 16 - 2025 | doi: 10.3389/fendo.2025.1661856

This article is part of the Research TopicNew Advances in Biomedical Research on Sex, Gender & Gender IncongruenceView all 7 articles

New Advances in Biomedical Research on Sex, Gender, and Gender Incongruence: A Multifaceted Perspective

Provisionally accepted
  • 1Department of Psychiatry, University Medical Centre Groningen, Hanzeplein 1, 9713 GZ Groningen, the Netherlands, Groningen, Netherlands
  • 2CICA - Interdisciplinary Centre for Chemistry and Biology Institute, Department of Psychology, University of A Coruña, A Coruña, Spain, A Coruña, Spain
  • 3Instituto de Investigación Biomédica de A Coruña (INIBIC), Oza, A Coruña 15071, Spain, A Coruña, Spain

The final, formatted version of the article will be published soon.

A significant theme emerging from this collection is the profound impact of genderaffirming hormone therapy (GAHT) on various physiological systems. Tienforti et al. In conclusion, this collection of articles represents significant advances in biomedical research on sex, gender, and gender incongruence. From elucidating the physiological and neurological impacts of GAHT to addressing the critical mental health needs and developing refined assessment tools, these studies collectively demonstrate the multifaceted nature of gender identity and the gender affirmation process. They underscore the need for sustained interdisciplinary research that integrates insights from endocrinology, neuroscience, psychology, and public health.

Keywords: Gender Incongruence, gender identity, GAHT, AMAB: Assigned Male At Birth, AFAB: Assigned Female At Birth

Received: 08 Jul 2025; Accepted: 14 Jul 2025.

Copyright: © 2025 Burke and Fernández. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Sarah M Burke, Department of Psychiatry, University Medical Centre Groningen, Hanzeplein 1, 9713 GZ Groningen, the Netherlands, Groningen, Netherlands
Rosa Fernández, CICA - Interdisciplinary Centre for Chemistry and Biology Institute, Department of Psychology, University of A Coruña, A Coruña, Spain, A Coruña, Spain

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