Frontiers in Genetics

Original Research

Published on 05 Mar 2025

Genetic discrimination in insurance and employment based on personalized risk stratification for breast cancer screening

in ELSI in Science and Genetics

Manuela Reveiz
Sarah Bouhouita-Guermech
Kristina M. Blackmore
Jocelyne Chiquette
Éric Demers
Michel Dorval
Laurence Lambert-Côté
Hermann Nabi
Nora Pashayan
Penny Soucy

Frontiers in Genetics

doi 10.3389/fgene.2025.1481863

4,642 views
4 citations

Case Report

Published on 05 Mar 2025

A novel HMBS gene mutation in acute intermittent porphyria: a case report of abdominal pain, seizures, and reversible neuroimaging findings

in Neurogenomics

Wentao Dong
Bingliang Zeng
Xiaolian Wang
Rui Zhang
Pei Huang
Bing Fan
Min Yuan
Zicong Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1551832

2,158 views

Original Research

Published on 05 Mar 2025

Expression quantitative trait loci associated with performance traits, blood biochemical parameters, and cytokine profile in pigs

in Livestock Genomics

Felipe André Oliveira Freitas
Luiz F. Brito
Bárbara Silva-Vignato
Fernanda Nery Ciconello
Vivian Vezzoni de Almeida
Aline Silva Mello Cesar

Frontiers in Genetics

doi 10.3389/fgene.2025.1533424

2,138 views
2 citations

Review

Published on 05 Mar 2025

Sex differences in asthma: omics evidence and future directions

in Applied Genetic Epidemiology

Bichen Peng
Weiyi Ye
Shuai Liu
Yue Jiang
Ziang Meng
Miao Guo
Lili Zhi
Xiao Chang
Lei Shao

Frontiers in Genetics

doi 10.3389/fgene.2025.1560276

4,291 views
6 citations

Brief Research Report

Published on 05 Mar 2025

Application of a novel RNA-protein interaction assay to develop inhibitors blocking RNA-binding of the HuR protein

in RNA

Larissa Filcenkova
Annika Reisbitzer
Benjamin Philipp Joseph
Verena Weber
Paolo Carloni
Giulia Rossetti
Sybille Krauß

Frontiers in Genetics

doi 10.3389/fgene.2025.1549304

3,787 views

Review

Published on 05 Mar 2025

Mechanism of action of lncRNA-NEAT1 in immune diseases

in RNA

Ruo-Xuan Zhang
Zi-Xuan Zhang
Xiang-Yu Zhao
Yi-Han Liu
Xiao-Meng Zhang
Qin Han
Xiao-Yu Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1501115

5,062 views
9 citations

Brief Research Report

Published on 05 Mar 2025

Experiences from dual genome next-generation sequencing panel testing for mitochondrial disorders: a comprehensive molecular diagnosis

in Genetics of Common and Rare Diseases

Elizabeth Gorman
Hongzheng Dai
Yanming Feng
William James Craigen
David C. Y. Chen
Fan Xia
Linyan Meng
Pengfei Liu
Robert Rigobello
Arpita Neogi

Frontiers in Genetics

doi 10.3389/fgene.2025.1488956

9,262 views
2 citations

Original Research

Published on 05 Mar 2025

Differential responses of the intestine and liver transcriptome to high levels of plant proteins in diets for large yellow croaker (Larimichthys crocea)

in Livestock Genomics

Qiaozhen Ke
Yin Li
Huasong Weng
Baohua Chen
Jiaying Wang
Ji Zhao
Pengxin Jiang
Peng Xu
Tao Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1540305

2,290 views
4 citations

Editorial

Published on 05 Mar 2025

Editorial: The role of genes and network pharmacology in new drug discovery

in Computational Genomics

Jingxin Mao

Frontiers in Genetics

doi 10.3389/fgene.2025.1578094

2,578 views
3 citations

Case Report

Published on 05 Mar 2025

Lessons from a phenotypically normal infant with uniparental isodisomy of chromosome 21: a Case Report and review

in Cytogenomics

Yuying Zhu
Ke Wu
Cuicui Jiang
Qiumin Zhu

Frontiers in Genetics

doi 10.3389/fgene.2025.1544565

2,323 views
1 citation

Original Research

Published on 05 Mar 2025

Molecular diagnosis and preimplantation genetic testing for chromosome 1q21.1 recurrent microduplication

in Genetics of Common and Rare Diseases

Cuiting Peng
Han Chen
Fan Zhou
Hong Yang
Yutong Li
Yuezhi Keqie
Xu Zhao
He Wang
Ting Hu
Shanling Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1522406

2,543 views

Original Research

Published on 05 Mar 2025

Identifying pathological myopia associated genes with GenePlexus in protein-protein interaction network

in Genetics of Common and Rare Diseases

Yuanyuan Luo
Yihan Wang
Lin Liu
Feiming Huang
Shiheng Lu
Yan Yan

Frontiers in Genetics

doi 10.3389/fgene.2025.1533567

2,930 views
3 citations

Original Research

Published on 05 Mar 2025

Identification of four key genes related to the diagnosis of chronic obstructive pulmonary disease using bioinformatics analysis

in Applied Genetic Epidemiology

Jinxia Li
Xiuming Liu
Yonghu Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1499996

2,967 views
2 citations

Original Research

Published on 04 Mar 2025

Development and validation of prognostic and diagnostic models utilizing immune checkpoint-related genes in public datasets for clear cell renal cell carcinoma

in Human and Medical Genomics

Bin Zhao
Shi Fu
Yuanlong Shi
Jinye Yang
Chengwei Bi
Libo Yang
Yong Yang
Xin Li
Zhiyu Shi
Yuanpeng Duan

Frontiers in Genetics

doi 10.3389/fgene.2025.1521663

3,114 views

Hypothesis and Theory

Published on 04 Mar 2025

Assessment of the causal association between obstructive sleep apnea and telomere length: a bidirectional mendelian randomization study

in Statistical Genetics and Methodology

Rongfang Xie
Shiyu Chen
Xiaojian Li
Zhihui Lan

Frontiers in Genetics

doi 10.3389/fgene.2025.1294105

2,549 views
1 citation

Original Research

Published on 03 Mar 2025

Identification of biomarkers and target drugs for melanoma: a topological and deep learning approach

in Cancer Genetics and Oncogenomics

Xiwei Cui
Jipeng Song
Qingfeng Li
Jieyi Ren

Frontiers in Genetics

doi 10.3389/fgene.2025.1471037

3,095 views
3 citations

Original Research

Published on 03 Mar 2025

Identification of QTL for branch traits in soybean (Glycine max L.) and its application in genomic selection

in Genomics of Plants and the Phytoecosystem

Qichao Yang
Jing Wang
Yajun Xiong
Alu Mao
Zhiqing Zhang
Yijie Chen
Shirui Teng
Zhiyu Liu
Jun Wang
Jian Song

Frontiers in Genetics

doi 10.3389/fgene.2025.1484146

2,338 views

Original Research

Published on 03 Mar 2025

A group penalization framework for detecting time-lagged microbiota-host associations

in Statistical Genetics and Methodology

Emily Palmer
Austin Hammer
Thomas Sharpton
Yuan Jiang

Frontiers in Genetics

doi 10.3389/fgene.2025.1504443

1,608 views

Original Research

Published on 03 Mar 2025

Causal effects of metabolites on malignant neoplasm of bone and articular cartilage: a mendelian randomization study

in Statistical Genetics and Methodology

Yongwei Du
Xiqiu Xiao
Fuping Liu
Wenqing Zhu
Jianwen Mo
Zhen Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1366743

2,164 views
1 citation

Methods

Published on 03 Mar 2025

STsisal: a reference-free deconvolution pipeline for spatial transcriptomics data

in Computational Genomics

Yinghao Fu
Leqi Tian
Weiwei Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1512435

3,108 views

Case Report

Published on 28 Feb 2025

Case Report: A case of progressive encephalopathy with or without lipodystrophy caused by BSCL2 variant and literature review

in Genetics of Common and Rare Diseases

Yao Wang
Jing Guo
Peiqi Zhang
Fang Liu
Hua Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1528563

2,147 views

Original Research

Published on 28 Feb 2025

Combined metabolome and transcriptome analysis provides molecular insights into reproductive process in Chuanxiang Black and Landrace pigs

in Livestock Genomics

Jiangling Li
Jinling Zhang
Sujun Zhao
Qiushi Wang
Rui Liu
Xiaohui Chen
Zhiping He

Frontiers in Genetics

doi 10.3389/fgene.2025.1501876

2,070 views

Case Report

Published on 28 Feb 2025

Case report: Whole exome sequencing identifies a novel variant in the HPRT1 gene in a male with developmental delay

in Genetics of Common and Rare Diseases

Haoyang Zheng
Gui Chen
Tingting Wang
Weisheng Cheng
Jing Yuan
Fang Liu
Yuanhong Xu

Frontiers in Genetics

doi 10.3389/fgene.2025.1512070

2,667 views

Review

Published on 28 Feb 2025

Verbal consent in biomedical research: moving toward a future standard practice?

in ELSI in Science and Genetics

Alycia Noë
Emilie Vaillancourt
Ma’n H. Zawati

Frontiers in Genetics

doi 10.3389/fgene.2025.1472655

4,364 views
5 citations

16,551 articles

articles

Genetic discrimination in insurance and employment based on personalized risk stratification for breast cancer screening

A novel HMBS gene mutation in acute intermittent porphyria: a case report of abdominal pain, seizures, and reversible neuroimaging findings

Expression quantitative trait loci associated with performance traits, blood biochemical parameters, and cytokine profile in pigs

Sex differences in asthma: omics evidence and future directions

Application of a novel RNA-protein interaction assay to develop inhibitors blocking RNA-binding of the HuR protein

Mechanism of action of lncRNA-NEAT1 in immune diseases

Experiences from dual genome next-generation sequencing panel testing for mitochondrial disorders: a comprehensive molecular diagnosis

Differential responses of the intestine and liver transcriptome to high levels of plant proteins in diets for large yellow croaker (Larimichthys crocea)

Editorial: The role of genes and network pharmacology in new drug discovery

Lessons from a phenotypically normal infant with uniparental isodisomy of chromosome 21: a Case Report and review

Molecular diagnosis and preimplantation genetic testing for chromosome 1q21.1 recurrent microduplication

Identifying pathological myopia associated genes with GenePlexus in protein-protein interaction network

Identification of four key genes related to the diagnosis of chronic obstructive pulmonary disease using bioinformatics analysis

Development and validation of prognostic and diagnostic models utilizing immune checkpoint-related genes in public datasets for clear cell renal cell carcinoma

Assessment of the causal association between obstructive sleep apnea and telomere length: a bidirectional mendelian randomization study

Identification of biomarkers and target drugs for melanoma: a topological and deep learning approach

Identification of QTL for branch traits in soybean (Glycine max L.) and its application in genomic selection

A group penalization framework for detecting time-lagged microbiota-host associations

Causal effects of metabolites on malignant neoplasm of bone and articular cartilage: a mendelian randomization study

STsisal: a reference-free deconvolution pipeline for spatial transcriptomics data

Case Report: A case of progressive encephalopathy with or without lipodystrophy caused by BSCL2 variant and literature review

Combined metabolome and transcriptome analysis provides molecular insights into reproductive process in Chuanxiang Black and Landrace pigs

Case report: Whole exome sequencing identifies a novel variant in the HPRT1 gene in a male with developmental delay

Verbal consent in biomedical research: moving toward a future standard practice?