Frontiers in Genetics | Cancer Genetics and Oncogenomics

Original Research

Published on 12 Nov 2025

CELF1 promotes aerobic glycolysis and an aggressive phenotype in ER-positive breast cancer via GLUT1 regulation

in Cancer Genetics and Oncogenomics

Jinyu Li
Ning Wang
Jianlei Bi
Meihua Guo
Bingbing Xu
Gena Huang

Frontiers in Genetics

doi 10.3389/fgene.2025.1687066

394 views

Original Research

Accepted on 11 Nov 2025

Development of a senescence-related lncRNA signature in endometrial cancer based on multiple machine learning models

in Cancer Genetics and Oncogenomics

Jie Lin
Xuemei Lei
Yanhong Li
Xin Jiang
Feng Le Jiang
Aihua Guo
Xintong Cai
Xingming Ye
Yang Sun

Frontiers in Genetics

Original Research

Accepted on 11 Nov 2025

SHMT2 modulates the transcriptome and metabolism profiles to promote the tumor phenotypes of bladder cancer HT-1376 cells

in Cancer Genetics and Oncogenomics

Xiaobo Guo
Gang Li

Frontiers in Genetics

Original Research

Accepted on 10 Nov 2025

Development of a Prognostic Model Related to Mitochondria and programmed cell death related genes in Bladder Cancer

in Cancer Genetics and Oncogenomics

Xuwei Zhao
Hongyao Liu
Chao Wang
Fuyu Guo
Bin Yang

Frontiers in Genetics

Original Research

Published on 10 Nov 2025

Unveiling disulfidptosis-linked lncRNA signatures: insights into the immune microenvironment and drug responsiveness in oral squamous cell carcinoma

in Cancer Genetics and Oncogenomics

Xue Meng
Lichao Cao
Yantao Liu
Sihan Wang
Weixian Liu
Guangping Zhang
Siqi Guo
Fangyu Qi
Tingting Wang
Yuhe Xia

Frontiers in Genetics

doi 10.3389/fgene.2025.1650544

390 views

Original Research

Published on 07 Nov 2025

BRMS1L promotes chemotherapy sensitivity by inhibiting autophagy in breast cancer

in Cancer Genetics and Oncogenomics

Yuan Li
Dian Zhang
Junhao Zhao
Mei Yang
Yiping Wang
Peiyao Lee
Shaohua Qu

Frontiers in Genetics

doi 10.3389/fgene.2025.1670001

717 views

Original Research

Accepted on 05 Nov 2025

Revealing the key modules and potential prognostic markers of gastric cancer transformation based on weighted gene co-expression networks

in Cancer Genetics and Oncogenomics

Heng Li
Wen Li
Zhen Yang
Haiyu Liu
Xiaoping Zhang
Yufeng Zhao
Hao Gu

Frontiers in Genetics

Review

Accepted on 30 Oct 2025

The risk factors for chemotherapy myelosuppression in breast cancer: a systematic review and meta-analysis

in Cancer Genetics and Oncogenomics

Yuan yuan Zhu
De lan Zeng
Yang Li
Ni Li

Frontiers in Genetics

122 views

Review

Published on 28 Oct 2025

Computational models for pan-cancer classification based on multi-omics data

in Cancer Genetics and Oncogenomics

Jianlin Wang
Jiao Zhang
Xuebing Dai
Chaokun Yan
Caili Fang

Frontiers in Genetics

doi 10.3389/fgene.2025.1667325

899 views

Original Research

Accepted on 27 Oct 2025

Single-cell RNA-seq combined with bulk RNA-seq explores shared gene signatures between thyroid and breast cancers

in Cancer Genetics and Oncogenomics

Zhiping Feng
Liang He
Yang Xin
Anhao Wu
Jingnan Wang
Yongchun Zhou
Yuanhua Song

Frontiers in Genetics

199 views

Review

Published on 23 Oct 2025

Single-cell transcriptomics in metastatic breast cancer: mapping tumor evolution and therapeutic resistance

in Cancer Genetics and Oncogenomics

Xu Han
Xin Li
Ling Bai
Gangling Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1669741

1,862 views

Original Research

Published on 23 Oct 2025

A newly discovered Lnc-PDZD7-3 increased metastatic and proliferative potential of lung adenocarcinoma cells via modulating FN1/fibronectin signaling

in Cancer Genetics and Oncogenomics

Guodong Zhang
Jianbo Zhang
Fachang Yu
Xiaohe Hao

Frontiers in Genetics

doi 10.3389/fgene.2025.1618449

995 views

Original Research

Accepted on 22 Oct 2025

PANoptosis-Related gene clusters and prognostic risk model in clear cell renal cell carcinoma

in Cancer Genetics and Oncogenomics

Qiyue Zhao
Huadong Xie
Chaofu Li
Yanxiang Xiong
Yongyi Fan
Yuanbi Huang
Yi Zhan
Siping Zeng

Frontiers in Genetics

427 views

Original Research

Published on 21 Oct 2025

A novel mechanism by which c-MYC is aberrantly activated by epigenetic silencing of its antisense lncRNA in colon cancer

in Cancer Genetics and Oncogenomics

Xuming Hu
Ye Wei
Meiying Zhang
Chunfeng Dou
Liping Wang
Gul Zaib
Huixian Wu
Wang Guo
Xiaoyuan Wang
Shihao Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1552009

1,607 views

Original Research

Published on 21 Oct 2025

Recognition of HSPB8 as a potential therapeutic target for prostate cancer

in Cancer Genetics and Oncogenomics

Xun Fu
Yutao Wang
Hongjun Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1680674

1,414 views

Original Research

Published on 16 Oct 2025

Identification and validation of selenium metabolism-related genes in lung adenocarcinoma prognosis using bioinformatics analysis

in Cancer Genetics and Oncogenomics

Yun Chen
Ping Li
Yang Wang
Shuai Shen
Ni Chen
Hao Peng
Zheyuan Xu

Frontiers in Genetics

doi 10.3389/fgene.2025.1655262

1,200 views