Frontiers in Genetics | Cancer Genetics and Oncogenomics

Review

Published on 08 Oct 2025

Epigenetic and metabolic reprogramming via nanotechnology: a synergistic approach to cancer vaccination in lung tumors

in Cancer Genetics and Oncogenomics

Min Xu
Xialin Zhang
Xinlin Yu
Cheng Ma
Xinwei Li
Gang Chen
Gang Yuan
Sheng Lin
Ran Cui

Frontiers in Genetics

doi 10.3389/fgene.2025.1666561

594 views

Original Research

Published on 08 Oct 2025

Pain - related methylation driver genes affect the prognosis of pancreatic cancer patients by altering immune function and perineural infiltration

in Cancer Genetics and Oncogenomics

Chencheng Zhang
Weiwei Xu
Xudong Chen
Xingdan Wang
Xiaopeng Cui
Wenjing Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1600883

492 views

Correction

Published on 07 Oct 2025

Correction: FEZF1-AS1 drives autophagy-mediated progression of colon cancer and reduces chemosensitivity through inhabiting the PI3K/AKT/mTOR signaling pathway

in Cancer Genetics and Oncogenomics

Xiaoping Yang
Zuohui Yuan
Lingzhu Gou
Long Cheng
Zirui Wang
Pingfan Wu
Xiaochun Wang
Xueni Ma
Tiantian Ma
Yi Yu

Frontiers in Genetics

doi 10.3389/fgene.2025.1684479

743 views

Original Research

Accepted on 06 Oct 2025

Identification and validation of selenium metabolism-related genes in lung adenocarcinoma prognosis using bioinformatics analysis

in Cancer Genetics and Oncogenomics

Yun Chen
Ping Li
Yang Wang
Shuai Shen
Ni Chen
Hao Peng
Zheyuan Xu

Frontiers in Genetics

doi 10.3389/fgene.2025.1655262

131 views

Review

Accepted on 06 Oct 2025

Single-Cell Transcriptomics in Metastatic Breast Cancer: Mapping Tumor Evolution and Therapeutic Resistance

in Cancer Genetics and Oncogenomics

Xu Han
Xin Li
Ling Bai
Gangling Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1669741

157 views

Original Research

Accepted on 03 Oct 2025

A novel mechanism by which c-MYC is aberrantly activated by epigenetic silencing of its antisense lncRNA in colon cancer

in Cancer Genetics and Oncogenomics

Xuming Hu
Ye Wei
Meiying Zhang
Chunfeng Dou
Liping Wang
Gul Zaib
Huixian Wu
Wang Guo
Xiaoyuan Wang
Shihao Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1552009

220 views

Brief Research Report

Accepted on 03 Oct 2025

A Rare Subtype of Lynch Syndrome Familial with Co-mutation of EpCAM c.344T>C, MSH2 c.2744A>G, PMS2 c.1408C>T and APC c.5465T>A, Case Report and Literature Review

in Cancer Genetics and Oncogenomics

Gui yu Lu
Ting Pan
Cui dong Deng
Xiao qian Wan
Zi han Wang
Teng yue Hu
Jian Dong
Xian shuo Cheng

Frontiers in Genetics

doi 10.3389/fgene.2025.1667899

161 views

Original Research

Accepted on 02 Oct 2025

HSPB8: a Potential Biomarker for Prostate Cancer Recognition of HSPB8 as a Potential Therapeutic Target for Prostate Cancer

in Cancer Genetics and Oncogenomics

Xun Fu
Yutao Wang
Hongjun Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1680674

247 views

Original Research

Published on 01 Oct 2025

Identification and validation of calcium signaling pathway-related biomarkers in T1 and T2 lymph node metastatic gastric cancer

in Cancer Genetics and Oncogenomics

Mingzhi Cai
Xinyang Nie
Fenglin Cai
Xiuding Yang
Weilin Sun
Rupeng Zhang
Han Liang
Yonglin Yang
Li Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1653700

1,490 views

Methods

Published on 26 Sep 2025

CNAdjust: enhancing CNA calling accuracy through systematic baseline adjustment

in Cancer Genetics and Oncogenomics

Hangjia Zhao
Michael Baudis

Frontiers in Genetics

doi 10.3389/fgene.2025.1674138

1,952 views

Original Research

Published on 26 Sep 2025

Developing prognostic models for cholesterol-related genes linked with immune infiltration in prostate cancer

in Cancer Genetics and Oncogenomics

Jie Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1604113

1,712 views

Original Research

Published on 25 Sep 2025

MK2-mediated AKT/MYC signaling activation promotes epithelial-mesenchymal transition in lung adenocarcinoma

in Cancer Genetics and Oncogenomics

Rong Qi
Chen Fang
Penghui Liu
Weiguo Gu
Chao Shi
Guohua Zhang
Feng Qiu

Frontiers in Genetics

doi 10.3389/fgene.2025.1615018

1,715 views

Original Research

Published on 24 Sep 2025

Identifying metabolism-related genes in liver cancer through weighted gene co-expression network analysis and machine learning

in Cancer Genetics and Oncogenomics

Taorui Wang
Zijun Lai
Shengjun Tang
Lehang Lin
Mingjiao Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1654459

2,736 views

Original Research

Published on 22 Sep 2025

Constructing a novel mitochondrial-related gene signature for predicting survival and evaluating the tumor immune microenvironment in clear cell renal cell carcinoma

in Cancer Genetics and Oncogenomics

Jiaxuan Qin
Lijian Zhang
Bowen Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1543593

3,206 views

Original Research

Published on 22 Sep 2025

Next-generation sequencing of mitochondrial DNA reveals pathogenic variants and protective haplogroup D4 in esophageal cancer

in Cancer Genetics and Oncogenomics

Xiucheng Jiang
Lan Shi
Mei Zhao
Cui Chen
Tao Tang
Simeng Ji
Bingbing Lv
Lihua Jia
Shuhan Duan
Jinyue Ma

Frontiers in Genetics

doi 10.3389/fgene.2025.1643229

1,304 views

Original Research

Published on 19 Sep 2025

The potential impact of GLS and PDHA1 on tumor immunity and immunotherapy response in LUSC

in Cancer Genetics and Oncogenomics

Tianhe Ling
Jiahui Wu
Ling Xiaohao

Frontiers in Genetics

doi 10.3389/fgene.2025.1606111

1,342 views