Frontiers in Genetics | Cancer Genetics and Oncogenomics

Original Research

Published on 18 Sep 2025

Identification of prognostic and cellular senescence gene E2F1 of papillary thyroid carcinoma through bioinformatics analyses and experimental verification

in Cancer Genetics and Oncogenomics

Bin Yu
Shu-Yan Zhao
Yun-Hua Zhu
Jun-Jie Luo
Ke Zheng
Bin-Jie Shen
Yi-Lin Shen
Huan-Xin Zhong

Frontiers in Genetics

doi 10.3389/fgene.2025.1605385

379 views

Original Research

Published on 17 Sep 2025

Panoramic analysis of the biological function and clinical value of SLC38A2 in human cancers: a study based on pan-cancer and single-cell analysis

in Cancer Genetics and Oncogenomics

Mao Liao
Yuqing Rao
Molan Li
Jiayang Guo
Kun Guo
Kaiyue Li
Rui Zheng
Yifan Liu
Qianyi Wang
Manni Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1658299

269 views

Original Research

Published on 17 Sep 2025

Bioinformatics-based identification of differentially expressed genes in endometrial carcinoma: implications for early diagnosis and prognostic stratification

in Cancer Genetics and Oncogenomics

Liang Gao
Donglan Yuan
Aihua Huang
Hua Qian

Frontiers in Genetics

doi 10.3389/fgene.2025.1631060

384 views

Review

Accepted on 16 Sep 2025

Epigenetic and Metabolic Reprogramming via Nanotechnology: A Synergistic Approach to Cancer Vaccination in Lung Tumors

in Cancer Genetics and Oncogenomics

Min Xu
Xialin Zhang
Xinlin Yu
Cheng Ma
Xinwei Li
Gang Chen
Gang Yuan
Sheng Lin
Ran Cui

Frontiers in Genetics

doi 10.3389/fgene.2025.1666561

Original Research

Published on 16 Sep 2025

Identification and validation of three tumor suppressors associated with the immune response of acute myeloid leukemia

in Cancer Genetics and Oncogenomics

Yueyuan Pan
Guocai Wu
Chenchen Liu
Minggui Chen
Tian Xia
Yonghua Ma
Zhigang Yang
Ruiting Wen

Frontiers in Genetics

doi 10.3389/fgene.2025.1652142

1,554 views

Original Research

Accepted on 15 Sep 2025

Identification and validation of calcium signaling pathway-related biomarkers in T1 and T2 lymph node metastatic gastric cancer

in Cancer Genetics and Oncogenomics

Mingzhi Cai
Xinyang Nie
Fenglin Cai
Xiuding Yang
Weilin Sun
Rupeng Zhang
Han Liang
Li Zhang
Yonglin Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1653700

262 views

Original Research

Published on 15 Sep 2025

Characterization of the phenotype and function of PRELP+ fibroblast subtype in liver metastatic colorectal cancer

in Cancer Genetics and Oncogenomics

Yuting Dai
Xingying Huang
Min Sun
Shiyu Zhang
Weiqiang Yu
Kongwang Hu
Qiang Wu
Qingfa Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1615259

550 views

Methods

Published on 15 Sep 2025

Construction of a novel prognostic model for gastric cancer based on pharmacokinetics-related genes and comprehensive prognostic analysis

in Cancer Genetics and Oncogenomics

Yu Zhang
Kai Jia
Yuntong Guo
Xiaole Ma
Tian Yao
Feng Wu
He Huang

Frontiers in Genetics

doi 10.3389/fgene.2025.1541401

373 views

Methods

Accepted on 10 Sep 2025

CNAdjust: Enhancing CNA Calling Accuracy through Systematic Baseline Adjustment

in Cancer Genetics and Oncogenomics

Hangjia Zhao
Michael Baudis

Frontiers in Genetics

doi 10.3389/fgene.2025.1674138

450 views

Original Research

Published on 09 Sep 2025

Genetic heterogeneity in childhood leukemia/lymphoma: a Turkish cohort with strong predisposition

in Cancer Genetics and Oncogenomics

Gizem Onder
Ozkan Ozdemir
Fulya Taylan
Cengiz Canpolat
Koray Yalcin
Fatih Erbey
Banu Oflaz Sozmen
Fikret Asarcikli
Turan Bayhan
Yunus Murat Akcabelen

Frontiers in Genetics

doi 10.3389/fgene.2025.1624306

2,170 views

Original Research

Published on 09 Sep 2025

ZC3H18 regulates alternative splicing and related genes in cervical cancer

in Cancer Genetics and Oncogenomics

Wenjuan Chen
Chenying Liu
Siyi Li
Xingyun Xie
Dan Hu
Yaobin Lin

Frontiers in Genetics

doi 10.3389/fgene.2025.1621238

877 views

Original Research

Published on 08 Sep 2025

A lipid metabolism and lysosome-based risk signature for prognosis and immune response prediction in uterine corpus endometrial carcinoma

in Cancer Genetics and Oncogenomics

Yuanyuan Zhu
Pusheng Yang
Shu Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1594682

721 views

Correction

Accepted on 05 Sep 2025

Correction: FEZF1-AS1 drives autophagy-mediated progression of colon cancer and reduced chemosensitivity through inhabiting PI3K/AKT/mTOR signaling pathway

in Cancer Genetics and Oncogenomics

Xiaoping Yang
Zuohui Yuan
Lingzhu Gou
Long Cheng
Zirui Wang
Pingfan Wu
Wang Xiaochun
Xueni Ma
Tiantian Ma
Yi Yu

Frontiers in Genetics

doi 10.3389/fgene.2025.1684479

455 views

Original Research

Published on 05 Sep 2025

Assembly factor for spindle microtubules (ASPM) promotes osimertinib resistance in lung cancer by increasing EGFR stability

in Cancer Genetics and Oncogenomics

Pengpeng Gui
Zhengyi Han
Zhenyu Yin
Peng Cao
Xin Zhou
Yan Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1593314

1,401 views

Original Research

Accepted on 04 Sep 2025

MK2-Mediated AKT/MYC Signaling Activation Promotes Epithelial-Mesenchymal Transition in Lung Adenocarcinoma

in Cancer Genetics and Oncogenomics

RONG QI
Chen Fang
Penghui Liu
Weiguo Gu
Chao Shi
Guohua Zhang
Feng Qiu

Frontiers in Genetics

doi 10.3389/fgene.2025.1615018

310 views

Original Research

Accepted on 01 Sep 2025

Constructing a novel mitochondrial-related gene signature for predicting survival and evaluating the tumor immune microenvironment in clear cell renal cell carcinoma

in Cancer Genetics and Oncogenomics

Jiaxuan Qin
Lijian Zhang
Bowen Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1543593

322 views