Frontiers in Genetics | Cancer Genetics and Oncogenomics

Original Research

Published on 25 Apr 2025

A rare germline mutation reverses the suppressive effect of GPC5 thereby promoting lung adenocarcinoma development and tumorigenesis

in Cancer Genetics and Oncogenomics

Zhifa Zheng
Lina Zhao
Sen Zhao
Zhihong Wu
Nan Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1582504

Original Research

Accepted on 24 Apr 2025

Prognosis of cholangiocarcinoma patients based on multiple patterns of programmed cell death, integrated analysis of the immune microenvironment and drug sensitivity

in Cancer Genetics and Oncogenomics

Yupeng Xu
Jian Sun
Xin Yan
Zhenliao Mao
Yiming Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1457204

Original Research

Accepted on 23 Apr 2025

RNA hybrid-capture next-generation sequencing has high sensitivity in identifying known and less characterized oncogenic and likely oncogenic NTRK fusions in a real-world standard-of-care setting

in Cancer Genetics and Oncogenomics

Zachary D Wallen
Marni Tierno
Erica Schnettler
Alison Roos
Michelle Green
Kobina Amoah
Rebecca A Previs
Stephanie Hastings
Sarabjot Pabla
Taylor J Jensen

Frontiers in Genetics

doi 10.3389/fgene.2025.1550706

Review

Accepted on 23 Apr 2025

In vitro 3D modeling of colorectal cancer: the pivotal role of the extracellular matrix, stroma and immune modulation

in Cancer Genetics and Oncogenomics

Veroniaina Hanitrarimalala
Zdenka Prgomet
My Hedhammar
Helena Tassidis
Anette Gjörloff Wingren

Frontiers in Genetics

doi 10.3389/fgene.2025.1545017

Original Research

Published on 22 Apr 2025

RNA-seq analysis reveals key genes associated with downregulation of APE1 in esophageal squamous cell carcinoma

in Cancer Genetics and Oncogenomics

Alan Chu
Xiao Liu
Shijia Liu
Mengxi Li
Rui Song
Lanlan Gan
Yongtai Wang
Zongwen Liu
Chen Sun

Frontiers in Genetics

doi 10.3389/fgene.2025.1549371

240 views

Original Research

Published on 15 Apr 2025

The regulatory role of the circELMOD3-associated ceRNA network in the progression and prognosis of hepatocellular carcinoma

in Cancer Genetics and Oncogenomics

Deyuan Li
Meiliang Liu
Mingshuang Lai
Lijun Wang
Liling Wei
Siqian Wu
Si Liang
Shun Liu
Xiaoyun Zeng

Frontiers in Genetics

doi 10.3389/fgene.2025.1521360

552 views

Original Research

Accepted on 14 Apr 2025

Radiomic features and tumor immune microenvironment associated with anaplastic lymphoma kinase-rearranged lung adenocarcinoma and their prognostic value

in Cancer Genetics and Oncogenomics

Ying Han
Wenya Feng
Huaxin Li
Hua Wang
Zhaoxiang Ye

Frontiers in Genetics

doi 10.3389/fgene.2025.1581937

Original Research

Published on 14 Apr 2025

Identification of characteristic genes in cutaneous squamous cell carcinoma based on weighted gene co-expression network analysis

in Cancer Genetics and Oncogenomics

Qipeng Xiao
Pengfei Xu
Wenjun Xu
Qiuhe Song
Yousheng Mao

Frontiers in Genetics

doi 10.3389/fgene.2025.1470584

583 views

Original Research

Accepted on 09 Apr 2025

The mechanism of RNA methylation writing protein-related prognostic genes in lung adenocarcinoma based on bioinformatics

in Cancer Genetics and Oncogenomics

Sha Yin
guangyan Luo
Lei Luo

Frontiers in Genetics

doi 10.3389/fgene.2025.1541541

Review

Accepted on 07 Apr 2025

The research progress of colorectal cancer in multi-omics

in Cancer Genetics and Oncogenomics

Yongxia Cui
Shuangyan Han
Qinglian Wen

Frontiers in Genetics

doi 10.3389/fgene.2025.1533817

115 views

Original Research

Accepted on 07 Apr 2025

Expression and Clinical Significance of FANCI Gene in Pan-Cancer: A Comprehensive Analysis Based on Multi-Omics Data

in Cancer Genetics and Oncogenomics

Yunzheng Zhao
Qingyu Li
Jiajun Li
Yifeng Cui
Zhaoyang Lu

Frontiers in Genetics

doi 10.3389/fgene.2025.1542888

106 views

Original Research

Published on 07 Apr 2025

Immunogenic cell death genes in single-cell and transcriptome analyses perspectives from a prognostic model of cervical cancer

in Cancer Genetics and Oncogenomics

Li Ning
Xiu Li
Yating Xu
Yu Si
Hongting Zhao
Qinling Ren

Frontiers in Genetics

doi 10.3389/fgene.2025.1532523

745 views

Original Research

Published on 04 Apr 2025

Biological characteristics and prognosis of acute myeloid leukemia in elderly patients

in Cancer Genetics and Oncogenomics

Zhe Chen
Lina Ding
Jieni Yu
Jing Jin
Zhijian Zhang
Jiaping Fu
Pan Hong
Leihua Fu

Frontiers in Genetics

doi 10.3389/fgene.2025.1524177

489 views

Original Research

Published on 04 Apr 2025

Transcriptomic signature can distinguish chronic neutrophilic leukemia from ambiguous neutrophilic leukemias

in Cancer Genetics and Oncogenomics

Chao Guo
Zhen-Ling Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1556519

533 views

Original Research

Published on 04 Apr 2025

The gene signature linked to lactate metabolism predicts the prognosis and correlates with the immune status of head and neck squamous cell carcinoma

in Cancer Genetics and Oncogenomics

Jian Xiao
Wei Li
Guolin Tan
Ru Gao

Frontiers in Genetics

doi 10.3389/fgene.2025.1540841

543 views

Correction

Published on 03 Apr 2025

Corrigendum: Comprehensive profiling reveals distinct microenvironment and metabolism characterization of lung adenocarcinoma

in Cancer Genetics and Oncogenomics

Chang Li
Chen Tian
Yangyang Liu
Jinyan Liang
Yulan Zeng
Qifan Yang
Yuting Liu
Di Wu
Jingjing Wu
Juanjuan Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1585016

383 views