Frontiers in Hematology | Immunobiology and Immunotherapy

Case Report

Accepted on 08 Aug 2025

Case report: Severe HHV-6-related encephalitis following anti-CD19 CAR-T therapy: No evidence of HHV-6 reactivation in transduced CAR-T cells

in Immunobiology and Immunotherapy

Nina Marie Birk
Katrine Kielsen
Özcan Met
Eva Kannik Haastrup
Thomas Morgan Hulen
Cecilie Ø Madsen
Torben Barington
Jonas Nielsen
Kristian Schønning
Søren Lykke Petersen

Frontiers in Hematology

doi 10.3389/frhem.2025.1628552

101 views

Case Report

Published on 24 Jul 2025

Balance and management of CRS and infection following CD19-targeted CAR T-cell therapy in primary refractory high-grade B-cell lymphoma: a case report

in Immunobiology and Immunotherapy

Nannan Lu
Yajing Zhang
Chunmeng Wang
Qingming Yang
Guanghua Rong
Yang Liu
Weidong Han

Frontiers in Hematology

doi 10.3389/frhem.2025.1616504

593 views

Review

Published on 23 Jun 2025

Advances in Chimeric Antigen Receptor T-cell therapy for hematologic malignancies and autoimmune conditions: a review of the 2024 American Society of Hematology Annual Meeting

in Immunobiology and Immunotherapy

Samuel Davis
Forat Lutfi

Frontiers in Hematology

doi 10.3389/frhem.2025.1610794

811 views

Case Report

Published on 24 Apr 2025

Case Report: Teclistamab in the treatment of idiopathic immune thrombocytopenia in patients with multiple myeloma

in Immunobiology and Immunotherapy

Asis Shrestha
Anup Kumar Trikannad Ashwini Kumar
Soumya Pandey
Tanvi Patel
Hira Imad Cheema
Syed Mujtaba Naqvi
Ramya Bachu
Trilok Shrivastava
Sharmilan Thanendrarajan
Maurizio Zangari

Frontiers in Hematology

doi 10.3389/frhem.2025.1547209

1,225 views

Editorial

Published on 24 Jan 2025

Editorial: Two decades of targeted therapies in hematology: new targets and novel combinations

in Immunobiology and Immunotherapy

Bruno António Cardoso
Natalia Neparidze

Frontiers in Hematology

doi 10.3389/frhem.2025.1548984

1,135 views

Original Research

Published on 26 Dec 2024

Unique target binding by the C-terminal region of FHR1 provides a new perception of aHUS pathology

in Immunobiology and Immunotherapy

Luce Perie
Selina Stippa
Christoph Saffer
Andrea Hartmann
Mathias Mörgelin
Svante L. H. Zipfel
Marc Thilo Figge
Thorsten Wiech
Christine Skerka
Peter F. Zipfel

Frontiers in Hematology

doi 10.3389/frhem.2024.1469176

1,183 views
2 citations

Brief Research Report

Published on 17 Jun 2024

Novel cryopreservation medium for enhanced stability of T cells at −80°C

in Immunobiology and Immunotherapy

WenXuan Zhou
Chen Wang
Yao Shi
Yi Pan
XiaDuo Meng
XunLei Kang
Xu Han

Frontiers in Hematology

doi 10.3389/frhem.2024.1346627

2,517 views
2 citations

Review

Published on 08 Mar 2024

Management of secondary immunodeficiency in hematological malignancies: a Delphi consensus from the Middle East

in Immunobiology and Immunotherapy

Maria Dimou
Mohamed Abuzakouk
Mona Al Ahmad
Khalil Al Farsi
Ahmad Alhuraiji
Fayhan Al Roqi
Ahmed Alsaeed
Mohsen Alzahrani
Ali Bazarbachi
Honar Cherif

Frontiers in Hematology

doi 10.3389/frhem.2024.1347708

2,585 views
1 citation

Clinical Trial

Published on 09 Nov 2023

4SCAR2.0 therapy for the management of post-transplantation relapse of B-cell acute lymphoblastic leukemia

in Immunobiology and Immunotherapy

Rui Zhang
Juan Xiao
Yuan Sun
Sanfang Tu
Yuhua Li
Leping Zhang
Yifei Cheng
Song Xue
Yongping Zhang
Bin Wang

Frontiers in Hematology

doi 10.3389/frhem.2023.1251622

1,038 views

Original Research

Published on 25 Aug 2023

Drug exporter expression correlates with group 3 innate lymphoid cell resistance to immunosuppressive agents

in Immunobiology and Immunotherapy

Said Z. Omar
Nienke J. E. Haverkate
Vera van Hoeven
Bianca Blom
Mette D. Hazenberg

Frontiers in Hematology

doi 10.3389/frhem.2023.1144418

947 views

Review

Published on 10 Aug 2023

The link between immune thrombocytopenia and the cytokine profile: a bridge to new therapeutical targets

in Immunobiology and Immunotherapy

Mihaela Andreescu

Frontiers in Hematology

doi 10.3389/frhem.2023.1191178

4,679 views
7 citations

Review

Published on 03 Aug 2023

Abatacept and T-cell costimulation blockade—shifting the paradigm in the prevention of graft-versus-host disease

in Immunobiology and Immunotherapy

Suparno Chakrabarti
Sarita Rani Jaiswal

Frontiers in Hematology

doi 10.3389/frhem.2023.1243247

2,603 views
2 citations

Case Report

Published on 15 May 2023

Case Report: Thrombopoietin receptor agonists in resistant thrombocytopenia in pregnancy: a case series and review of literature

in Immunobiology and Immunotherapy

Gamal Sayed
Sarah A. ElKourashy
Mohammed Alnajjar
Naela Al Mallahi
Shehab Fareed

Frontiers in Hematology

doi 10.3389/frhem.2023.1180156

2,949 views
3 citations

Original Research

Published on 10 May 2023

Post CAR T-cell therapy outcomes and management in HSCT-naive patients: a single-center experience

in Immunobiology and Immunotherapy

Christine L. Phillips
Christa Krupski
Ruby Khoury
Christopher E. Dandoy
Adam S. Nelson
Thomas J. Galletta
Angela Faulhaber
Stella M. Davies
Jeremy D. Rubinstein

Frontiers in Hematology

doi 10.3389/frhem.2023.1151744

1,831 views
1 citation

Original Research

Published on 07 Mar 2023

Identification factors to adjust early combination regimens in adult primary immune thrombocytopenia: An 8-year data analysis

in Immunobiology and Immunotherapy

Kunapa Iam-arunthai
Supat Chamnanchanunt
Pravinwan Thungthong
Chajchawan Nakhahes
Tawatchai Suwanban
Ponlapat Rojnuckarin

Frontiers in Hematology

doi 10.3389/frhem.2023.1135261

1,499 views

Case Report

Published on 19 Dec 2022

Case Report: A unique case of secondary hemophagocytic lymphohistiocytosis from ehrlichiosis infection

in Immunobiology and Immunotherapy

Swe Swe Hlaing
Christine Jane Kurian
Jennie Tan
Eric Behling
Ahmed Kamel Abou Hussein

Frontiers in Hematology

doi 10.3389/frhem.2022.1039821

2,767 views