CORRECTION article

Front. Immunol.

Sec. Viral Immunology

Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1428530

Corrigendum: The immune response to lumpy skin disease virus in cattle is influenced by inoculation route

Provisionally accepted
  • The Pirbright Institute, Woking, United Kingdom

The final, formatted version of the article will be published soon.

Corrigendum on: Fay PC, Wijesiriwardana N, Munyanduki H, Sanz-Bernardo B, Lewis I, Haga IR, Moffat K, van Vliet AHM, Hope J, Graham SP, Beard PM. The immune response to lumpy skin disease virus in cattle is influenced by inoculation route. Front Immunol. 2022 Nov 28;13:1051008. doi: 10.3389/fimmu.2022.1051008. PMID: 36518761; PMCID: PMC9742517.Recent analysis of blood samples from the directly-inoculated "donor" cattle described in this publication has identified the presence of pestivirus genome in venous blood samples from cattle D2, D3, D4 and D5, suggesting possible contamination of the challenge inoculum. No pestivirus genome was detected in blood samples from donor D1. No pestivirus genome was detected in blood samples from any of the ten arthropod-inoculated recipient cattle. The influence from the presence of pestivirus on the immune responses directed against LSDV in the directly-inoculated cattle D2, D3, D4 and D5 is unclear. The conclusions of the paper, particularly the importance of using the most relevant model possible when studying disease under experimental conditions, remain unchanged. The potential of pestivirus contamination of LSDV stocks is highlighted to the research community.

Keywords: humoral immunity, Lumpy Skin Disease, Bovine immunity, cell-mediated immunity, Neutralising antibodies, poxvirus, virus

Received: 06 May 2024; Accepted: 24 Jun 2025.

Copyright: © 2025 Beard. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Pip Beard, The Pirbright Institute, Woking, United Kingdom

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