CASE REPORT article
Front. Immunol.
Sec. Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders
Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1550919
This article is part of the Research TopicChronic Atrophic Gastritis: Pathogenesis, Diagnostic Challenges, and Gastric Cancer RiskView all 8 articles
Novel endoscopic characteristics of early-stage autoimmune gastritis from two cases: The fog is lifting
Provisionally accepted
- 1Ningbo First Hospital, Ningbo, Zhejiang Province, China
- 2Fenghua People's Hospital, Ningbo, Zhejiang Province, China
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With the development of the researches, the clinical characteristic of autoimmune gastritis (AIG) is becoming much more clearly. However, as its occult endoscopic appearance, it is still difficult to diagnose early even ultra-early AIG. More cases and typical clinical characteristics should be proposed and concluded to guide clinicians. Hence, we select two novel early AIG cases and summary their common endoscopic features in order to improve diagnostic ability. We found there are two interesting features for early AIG: (1) deep reticular blood vessels in the lower part of the cardia mucosa. (2) NBI magnification showed various manifestations of crypt opening, such as dilation, pinhole-like, shrinkage, and disappearance. Future studies promise even more progress with the hope that these features can be found in more cases.
Keywords: autoimmune gastritis1, gastrin2, clinical characteristic3, endoscopic appearence4, Case report5
Received: 03 Jan 2025; Accepted: 16 Sep 2025.
Copyright: © 2025 Yan and Song. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Yiming Song, 362324219@qq.com
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