REVIEW article
Front. Immunol.
Sec. Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders
Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1561926
Research Progress on complications of rheumatoid arthritis
Provisionally accepted
- Guangzhou Hospital of Integrated Traditional and Western Medicine, Guangzhou, China
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Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovial inflammation, joint injury, and deformity in the limbs. This disease is widely distributed, with a large number of patients, and there is a possibility of further increasing the number of patients in the current aging society. RA can cause complications in multiple systems, many of which can seriously affect patients' quality of life and even significantly increase the risk of death. The unclear mechanism of RA makes it difficult to achieve accurate prediction and treatment of its complications. Therefore, this article provides an overview of the research progress on the common or extensively studied complications of RA, such as joint injury, interstitial lung disease, vasculitis, osteoporosis, Sjogren's syndrome, malignant tumors, etc. It identifies the problems and shortcomings in research and proposes some suggestions for future measures, in order to raise awareness among medical professionals and the public about actively controlling these complications and provide some assistance.
Keywords: complications, Research progress, Rheu matism, autoimmune disease, Rheumatoid arthritis
Received: 16 Jan 2025; Accepted: 05 May 2025.
Copyright: © 2025 Zeng, Yuan, Wu and Huang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Zhisheng Huang, Guangzhou Hospital of Integrated Traditional and Western Medicine, Guangzhou, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.