CASE REPORT article
Front. Immunol.
Sec. Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders
Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1562853
Multiple Gastric Tumors in Patients with Combined Autoimmune and Helicobacter pylori-associated Gastritis: A Case Report and Literature Review
Provisionally accepted
- 1Department of Gastroenterology, The 900th Hospital of Chinese PLA Logistic Support Forces, Fuzhou, Fujian Province, China
- 2Fujian Medical University, Fuzhou, China
- 3Department of Pathology, The 900th Hospital of Chinese PLA Logistic Support Forces, Fuzhou, Fujian Province, China
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This paper presents four cases of autoimmune gastritis coexisting with Helicobacter pylori-associated gastritis, all of which developed gastric tumors, with some cases exhibiting multiple histological origins. Through a narrative literature review, we explore the potential mechanisms and clinical implications of tumor development in this context. This report emphasizes the significance of recognizing synergistic mucosal injury in chronic gastritis management and highlights the need for future studies into combined pathogenesis.
Keywords: autoimmune gastritis1, gastric cancer2, endoscopy3, helicobacter pylori4, Case report5
Received: 18 Jan 2025; Accepted: 29 Apr 2025.
Copyright: © 2025 Lin, Wu, Xu, Yi, Zhang, Li, Zheng, Li and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Wen Wang, Department of Gastroenterology, The 900th Hospital of Chinese PLA Logistic Support Forces, Fuzhou, 350009, Fujian Province, China
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