CASE REPORT article
Front. Immunol.
Sec. Cancer Immunity and Immunotherapy
Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1602186
This article is part of the Research TopicCancer Immunity and RadiotherapyView all 12 articles
The huge esophageal displacement: a case of dramatic esophageal interfraction motion during neoadjuvant chemotherapy and immunotherapy
Provisionally accepted
- National Cancer Center, Cancer Hospital Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, China
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The average movement of esophagus is about 0.15 to 0.4 cm radially and 0.3 to 0.9 cm in the superior-inferior during radiotherapy.Little study has reported giant shift of esophagus during neoadjuvant chemotherapy and immunotherapy.Case presentation: Here we presented a case of a 72-year-old male patient diagnosed with advanced lower thoracic esophageal squamous cell cancer, clinical T2N2M1, stage IVB (pulmonary metastasis). The esophagus moved about 4.2 cm radially from the right to the left of the aorta after 2 cycles of chemotherapy and immunotherapy.All in all, we treated a patient with advanced lower thoracic esophageal squamous cell cancer that occurred a dramatic radial escape of about 4.2 cm after 2 cycles of chemotherapy and immunotherapy.
Keywords: esophageal cancer, chemotherapy, Immunotherapy, motion, Radiotherapy
Received: 29 Mar 2025; Accepted: 26 Jun 2025.
Copyright: © 2025 Liang, Jin, Zhang and Liang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Jing Jin, National Cancer Center, Cancer Hospital Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, China
Jianghu Zhang, National Cancer Center, Cancer Hospital Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, China
Jun Liang, National Cancer Center, Cancer Hospital Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, China
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