REVIEW article
Front. Immunol.
Sec. Cancer Immunity and Immunotherapy
Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1613494
This article is part of the Research TopicExploring the Role of Exosomes in Cancer MetastasisView all 4 articles
Exosomal proteins: new targets for early diagnosis and treatment of cancer
Provisionally accepted
- 1First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi Province, China
- 2People's Hospital of Ganzhou Economic Development Zone, Ganzhou, Jiangxi Province, China
- 3Gannan Medical University, Ganzhou, Jiangxi Province, China
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Exosomes are nanoscale, double-membraned vesicles released by a variety of living cells. A wide variety of cargoes, including proteins, DNA and RNA, are transported by exosomes to target cells, thereby transmitting biological signals. In addition to being an essential component of the exosomal cargo, exosomal proteins are a reflection of the physiological state of the originating cell, and play an essential part in intercellular communication in numerous diseases, including cancer. The present review provides a summary of the novel uses of exosomal proteins in cancer diagnosis and prognosis, and highlights the distinct qualities that exosomal proteins possess, when compared with typical serological measurements.
Keywords: Exosomes, Exosomal proteins, biomarkers, cancer diagnosis, Treatment
Received: 17 Apr 2025; Accepted: 09 Jun 2025.
Copyright: © 2025 Shen, Liu, Yang, Xiao, Peng, Rao and Huang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Defa Huang, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi Province, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.