CASE REPORT article

Front. Immunol.

Sec. Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1627179

A case report of allergic eczematoid dermatitis allergic eczematoid dermatitis around hemodialysis access due to iodine-containing disinfectant

Provisionally accepted
Xiaomei LuXiaomei Lu1Jing HeJing He2Liansheng RenLiansheng Ren1Rong YangRong Yang1Shuhuan LiuShuhuan Liu1Jingying BaiJingying Bai2Yueqiu TangYueqiu Tang1Yi ZengYi Zeng1Yunmin WangYunmin Wang1Wei ZhangWei Zhang2*Dan ZhuDan Zhu1*
  • 1Department of Endocrine Neprology, 363 Hospitial, Chengdu, China
  • 2Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin, China

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We report here a case of allergic eczematoid dermatitis related to hemodialysis access. The patient was initially suspected to have puncture needle allergies or dialyzer reactions until the patient develops a similar response after switching from an arteriovenous fistula (AVF) to a tunneled cuffed catheter (TCC) for dialysis. Thereby, we highly suspected that the allergen was the iodine-containing disinfectant used prior to dialysis, and the patient was ultimately diagnosed with iodine-containing disinfectant allergy. The patient's dermatitis improved remarkably after switching to alcohol disinfection as well as taking oral steroids. Early identification and diagnosis of allergic reactions at the vascular access site can avoid contacting with allergens, 2 / 9 accordingly prevent complications like infection and loss of precious vascular accesses in these patients.

Keywords: hemodialysis, Arteriovenous Fistula, allergic eczematoid dermatitis, iodine-containing disinfectant, Tunneled cuffed catheter

Received: 12 May 2025; Accepted: 04 Jul 2025.

Copyright: © 2025 Lu, He, Ren, Yang, Liu, Bai, Tang, Zeng, Wang, Zhang and Zhu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Wei Zhang, Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin, China
Dan Zhu, Department of Endocrine Neprology, 363 Hospitial, Chengdu, China

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