CORRECTION article

Front. Immunol.

Sec. Cancer Immunity and Immunotherapy

Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1630619

This article is part of the Research TopicAdvancements in Immune Heterogeneity in Inflammatory Diseases and Cancer: New Targets, Mechanisms, and StrategiesView all 15 articles

Corrigendum: Case Report: Multi-organ injuries induced by tislelizumab

Provisionally accepted
  • 1West China Hospital, Sichuan University, Chengdu, China
  • 2Suining Central Hospital, Suining, China

The final, formatted version of the article will be published soon.

"On evaluation at our institution, his body temperature was 36.5 °C, with a pulse of 110 beats per minute, blood pressure of 98/72 mmHg, and a breath of 20 times/min. Hematology showed a hemoglobin level of 88 g/L, a white blood cell count of 7.06×10 9 /L, 89.2 % neutrophils, and 6.9 % lymphocytes. Chest CT revealed a small mass (1.4 x 0.9 cm) in the anterior lobe of the left superior lung, bronchial wall truncation, and peripheral pleural stretch (Figure 1I)."The corrected sentence appears below: "[The patient was a 68-year-old man with a smoking history of 40 years. He had been diagnosed as having LUSC (cT3N0M0 IIB) by percutaneous needle lung biopsy in December 2023 at the local hospital. The pathology report showed P40 (+), pan-CK (AE1/AE3) (+), TTF-1 (-), NapsinA (-), CgA (-), CD56 (-), and Ki-67 (60 % +) (Figures 1A-F). A contrast-enhanced chest computed tomography (CT) scan revealed a subpleural soft tissue density shadow in the anterior segment of the left upper lobe, with a maximum cross-sectional dimension of approximately 3.4 x 3.1 cm (Figure 1G). Then he had undergone neoadjuvant chemotherapy with paclitaxel (400 mg d1), carboplatin (400 mg d1), and tislelizumab (200 mg d1; BeiGene, China) Q3W in December 2023 at the local hospital. The first session of treatment went well, with no significant adverse effects. After the second dose of treatment in February 2024, he developed hyperthyroidism and then hypothyroidism and was given metoprolol succinate followed by levothyroxine. A follow-up CT scan showed significant reduction in the mass size (Figure 1H). In March 2024, he experienced nausea, poor appetite, and abnormal liver function markers and was admitted to West China Hospital of Sichuan University in April 2024. The time axis of diagnosis and treatment of the patient is shown in Figure 2. Since November 2023, he had been on atorvastatin calcium and aspirin for cerebral infarction without limb movement issues. He stopped atorvastatin in March 2024 due to liver function abnormalities.On evaluation at our institution, his body temperature was 36.5 °C, with a pulse of 110 beats per minute, blood pressure of 98/72 mmHg, and a breath of 20 times/min. Hematology showed a hemoglobin level of 88 g/L, a white blood cell count of 7.06×10 9 /L, 89.2 % neutrophils, and 6.9 % lymphocytes. Chest CT revealed a small mass (1.4 x 0.9 cm) in the anterior lobe of the left superior lung, bronchial wall truncation, and peripheral pleural stretch (Figure 1I).]"The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Keywords: Lung squamous cell carcinoma, Immune-related adverse events, immune checkpoint inhibitors, tislelizumab, multi-organ injuries, case report

Received: 18 May 2025; Accepted: 29 May 2025.

Copyright: © 2025 Yuan, Han, Shu, Yan and Tang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Libo Yan, West China Hospital, Sichuan University, Chengdu, China

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.