EDITORIAL article
Front. Immunol.
Sec. Inflammation
Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1645760
This article is part of the Research TopicCommunity Series in Pathogenetic mechanism and therapeutic target for inflammation in autoimmune disease: Volume IIView all 10 articles
Editorial：Pathogenetic mechanism and therapeutic target for inflammation in autoimmune disease Volume II
Provisionally accepted
- 1Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
- 2Department of Rheumatology, Huashan Hospital, Fudan University, Shanghai, China
- 3Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Hefei, China
- 4Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
- 5College of Life Science and Technology, Xinjiang University, Urumqi, China
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Recent advances in basic research and clinical trials have indicated novel therapeutic approaches for autoimmune diseases. Breakthroughs in cytokine-targeting antibodies, small-molecule inhibitors, and cellular therapies are revolutionizing the management of inflammatory and autoimmune disorders (1)(2)(3)(4)(5)(6). The landmark success of mRNA vaccine technology further underscores the transformative potential of nucleic acid therapeutics (7,8). This therapeutic evolution marks a paradigm shift from broad immunosuppression to precision strategies that restore immune homeostasis, potentially enabling sustained disease remission or even cure (9). This second volume of Frontiers in Immunology's special issue presents nine papers that dissect molecular pathways, identify diagnostic biomarkers, and explore therapeutic strategies for autoimmune diseases. These works collectively advance our understanding of inflammation's multifaceted roles and highlight translational opportunities for precision medicine.
Keywords: Pathogenetic mechanism, therapy, autoimmune disease, Inflammation, target
Received: 12 Jun 2025; Accepted: 02 Jul 2025.
Copyright: © 2025 Li, Liang, Pan, Gao, Xu and Liangjing. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Lu Liangjing, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
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