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ORIGINAL RESEARCH article

Front. Immunol.

Sec. Systems Immunology

Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1656060

Microbiomic and metabolomic analysis of the effect of heat-sensitive moxibustion on allergic rhinitis in rats

Provisionally accepted
Jun  XiongJun Xiong1JIanheng  LiJIanheng Li2*Haiyan  XuHaiyan Xu2Yicheng  LiYicheng Li1Lunbin  LuLunbin Lu1Shuang  YangShuang Yang1
  • 1Nanchang University Second Affiliated Hospital, Nanchang, China
  • 2Jiangxi University of Traditional Chinese Medicine, Nanchang, China

The final, formatted version of the article will be published soon.

The original concept of acupoint sensitization theory was put forward in Huangdi Neijing, which believed that acupoints, as the reflecting parts of the body surface, were personalized, changeable and sensitive. heat-sensitive moxibustion have a good therapeutic effect on allergic rhinitis, but the mechanism is still unclear. Notably, acupoint sensitization in allergic rhinitis (AR) rats was accompanied by a distal thermal effect, with an increase in tail temperature (TTI) after 40 minutes of moxibustion.

Keywords: allergic rhinitis, biomarkers, Metabolomics, microbiome, multiomics

Received: 30 Jun 2025; Accepted: 14 Oct 2025.

Copyright: © 2025 Xiong, Li, Xu, Li, Lu and Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: JIanheng Li, 486511499@qq.com

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