REVIEW article
Front. Immunol.
Sec. Alloimmunity and Transplantation
This article is part of the Research TopicCancer in Kidney Transplant RecipientsView all 3 articles
Urothelial carcinoma following kidney transplantation: a narrative review of chineseChinese insights and challenges from pathogenesis to precision diagnosis and treatment
Provisionally accepted
- 1Peking University Third Hospital, Haidian, China
- 2Peking University People's Hospital, Beijing, China
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Kidney transplant recipients (KTRs) exhibit a higher incidence of neoplasms compared to the general population, primarily due to the prolonged administration of immunosuppressive agents and viral infections. In China, the primary type of tumor among KTRs is urothelial carcinoma (UC), which lacks specific clinical manifestations. Accurate diagnosis necessitates the integration of multiple diagnostic modalities, while therapeutic approaches must judiciously balance oncological control with the preservation of renal function, thereby presenting a considerable challenge to the health of KTRs. This article provides a comprehensive review of the epidemiological characteristics, risk factors, diagnostic methodologies, and therapeutic strategies associated with urothelial carcinoma post kidney transplantation (KT), aiming to enhance healthcare professionals' understanding of this condition and improve patient management.
Keywords: Kidney Transplantation, urothelial carcinoma, pathogenic characteristics, diagnosis, treatment strategies
Received: 17 Jul 2025; Accepted: 25 Nov 2025.
Copyright: © 2025 Li, Ren, Liu, Tian, Zhang, Wang, Zhang and Ma. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Shudong Zhang
Lulin Ma
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