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REVIEW article

Front. Immunol.

Sec. Vaccines and Molecular Therapeutics

Volume 16 - 2025 | doi: 10.3389/fimmu.2025.1687362

Research Progress on Vaccination During Pregnancy

Provisionally accepted
JIAO  ZHANGJIAO ZHANG1,2Zhimin  LiZhimin Li1Shiran  LiShiran Li1Pengfei  LiPengfei Li1,3Jingxian  XieJingxian Xie1,4Yong  YangYong Yang1*
  • 1Personalized Drug Research and Therapy Key Laboratory of Sichuan Province, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China
  • 2Department of Pharmacy, Chongqing Red Cross Hospital, Chongqing, China
  • 3Department of Pharmacy, Bishan Hospital of Chongqing Medical University, Chongqing, China
  • 4Southwest Medical University, Luzhou, China

The final, formatted version of the article will be published soon.

Pregnant women and infants are more vulnerable to infectious diseases than the general population.Vaccination during pregnancy can not only protect mothers and fetuses from diseases,but also safeguards infants through maternal antibodies transferred via the placenta. It stands as one of the most effective strategies to reduce the incidence and mortality of infectious diseases among pregnant women and infants.Globally, pregnancy vaccination strategies are increasingly diversified. This review discusses the effectiveness and safety of various vaccines for preventing infectious diseases during pregnancy, as well as vaccination recommendations for pregnant women across different countries.

Keywords: Pregnancy, Vaccination, maternal immunization, vaccine safety, vaccine efficacy

Received: 17 Aug 2025; Accepted: 13 Oct 2025.

Copyright: © 2025 ZHANG, Li, Li, Li, Xie and Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Yong Yang, yangyongforever@163.com

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.