EDITORIAL article
Front. Immunol.
Sec. Alloimmunity and Transplantation
This article is part of the Research TopicMulti-omics Assessment for the Discovery of Promising Novel Molecules in the Treatment of Transplant Organ InjuryView all 7 articles
Editorial: Multi-omics Assessment for the Discovery of Promising Novel Molecules in the Treatment of Transplant Organ Injury
Provisionally accepted
- 1Taizhou Hospital of Zhejiang Province, Linhai, China
- 2National Research Institute for Child Health and Development, Tokyo, Japan
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Transplant organ injury remains a critical clinical challenge that significantly impacts graft survival and recipient outcomes. The intricate interplay among ischemia-reperfusion injury (IRI), immune rejection, and chronic injury mechanisms highlights the pressing need to identify novel therapeutic molecules (1). The combination of genomics, transcriptomics, proteomics, and metabolomics technologies enables scientists to study organ injury at molecular network levels and discover therapeutic targets. The combination of multiple data types enables researchers to understand individual molecule functions and track how signaling pathways and metabolic changes and immune responses interact with each other to create a complete system for developing personalized treatments (2,3). The research topic showcases modern multi-omics applications for discovering new therapeutic compounds for transplant organ damage through six
Keywords: multi-omics, transplant, organ, injury, Ischemia-reperfusion, Precision, Medicine
Received: 11 Nov 2025; Accepted: 14 Nov 2025.
Copyright: © 2025 Liu, Li and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Xiao-Kang Li, ri-k@ncchd.go.jp
Shao-wei Li, li_shaowei81@hotmail.com
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.