Frontiers in Immunology

Original Research

Published on 17 Dec 2025

Induction of trained immunity in myeloid cells and their progenitors from thyroid cancer patients

in Cancer Immunity and Immunotherapy

Pepijn van Houten
Prashant Changoer
Liesbeth van Emst
Han J. Bonenkamp
Johannes H. W. de Wilt
Willemijn Hobo
Manita E. J. Bremmers
Mieke W. H. Roeven
Janneke E. W. Walraven
Petronella B. Ottevanger

Frontiers in Immunology

doi 10.3389/fimmu.2025.1706496

291 views

Review

Published on 17 Dec 2025

Research progress on recombinant NDV in cancer therapy

in Cancer Immunity and Immunotherapy

Jiating Sun
Jia Wang
Min Xiao
Liming Chen
Yi Guan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1735440

169 views

Review

Published on 17 Dec 2025

Beyond monoclonal antibodies: constraints and the case for alternative PD-1/PD-L1-targeting formats

in Cancer Immunity and Immunotherapy

Natalia O. Porozova
Natalia V. Petukhova
Maxim A. Gureev
Ivan S. Moiseev
Igor E. Eliseev
Ludmila V. Fedorova
Yuri B. Porozov

Frontiers in Immunology

doi 10.3389/fimmu.2025.1729468

242 views

Original Research

Published on 17 Dec 2025

Dynamic genetic regulation of CD4+ T cells in obstructive sleep apnea: integrating context-specific eQTL, Mendelian randomization, single-cell sequencing, and experimental validation

in Systems Immunology

Xinyue Zhang
Lingfei Ren

Frontiers in Immunology

doi 10.3389/fimmu.2025.1691347

285 views

Original Research

Published on 17 Dec 2025

OmniNeo: a multi-omics pipeline incorporating proteomics and AI selection for neoantigen optimization in tumor immunotherapy

in Vaccines and Molecular Therapeutics

Manman Lu
Yang Liu
Linfeng Xu
Yuan Gao
Peng Liu
Zhenhao Liu
Xiaoxiu Tan
Wenzhen Li
Yong Lin
Lanming Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1727642

288 views

Original Research

Published on 17 Dec 2025

A comparative study of large-vessel and small-vessel primary angiitis of the central nervous system: insights from a Chinese single-center retrospective cohort

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Yifan Wang
Jiangyi Lyu
Fangfang Li
Jing Zhao
Yu He
Shangtian Xiang
Weizhou Zang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1724588

219 views

Original Research

Published on 17 Dec 2025

COVID-19 vaccination induces cross-reactive dengue virus antibodies with altered isotype profiles and in vitro antibody-dependent enhancement

in Viral Immunology

Sebastian Reinig
Chin Kuo
Sheng-Yu Huang
Kuei-Ching Hsiung
Po-Kai Chen
Etsuro Ito
Ing-Kit Lee
Ching-Yen Tsai
Shu-Min Lin
Shin-Ru Shih

Frontiers in Immunology

doi 10.3389/fimmu.2025.1683070

1,117 views

Original Research

Accepted on 16 Dec 2025

The gut microbiota composition is shaped by disease activity and individual treatment responses in patients with multiple sclerosis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Veronika Ticha
Stepan Coufal
Zuzana Jiraskova Zakostelska
Tomas Thon
Radka Roubalova
Tomas Hrncir
Miloslav Kverka
Miluse Pavelcova
Pavlina Kleinova
Jana Lizrova Preiningerova

Frontiers in Immunology

317 views

Review

Accepted on 16 Dec 2025

The Infection–Microbiome–Immunity Axis in Bladder Cancer: Mechanistic Insights and Therapeutic Perspectives

in Cancer Immunity and Immunotherapy

Shen Pan
Zhujun Wang
Wanlin Cui
Bitian Liu

Frontiers in Immunology

185 views

Original Research

Accepted on 16 Dec 2025

Enhancing Named Entity Recognition for Immunology and Immune-Mediated Disorders

in Systems Immunology

Jinshan Che
Mingming Sun
Yuhong Wang

Frontiers in Immunology

114 views

Correction

Accepted on 16 Dec 2025

Correction: Antibodies and cryptographic hash functions: quantifying the specificity paradox

in Systems Immunology

Robert Petrella

Frontiers in Immunology

114 views

Editorial

Accepted on 16 Dec 2025

Editorial: Molecular Mechanisms of the Host Immune Response to Toxoplasma gondii Infection

in Parasite Immunology

Jing Yang
Rui Fang

Frontiers in Immunology

Original Research

Accepted on 16 Dec 2025

C-X-C motif chemokine ligand 13 suppresses osteoclast differentiation via interference with RANKL–RANK interaction

in Cytokines and Soluble Mediators in Immunity

Trung-Loc Ho
Kun-Tsan Lee
Yu-Hao He
Huynh Hoai Thuong Le
Achudhan David
Wei-Chien Huang
Chih-Yuan Ko
Chun-Lin Liu
Jeng-Hung Guo
Chih-Hsin Tang

Frontiers in Immunology

173 views

Original Research

Accepted on 16 Dec 2025

Vancomycin is a risk factor for acute pancreatitis and increases the mortality rate in patients with severe pancreatitis

in Comparative Immunology

Wang Yongxiang
He Hongye
Zou Heng
ZhongTao Liu
Yu Wen

Frontiers in Immunology

Review

Accepted on 16 Dec 2025

Aberrant B Cell Responses as Drivers of Autoantibody Generation and Epitope Diversification in SLE Pathogenesis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Fareeha Tariq
Yathavi Charavanmuttu
Kazi Labiba
Chris Wincup

Frontiers in Immunology

Original Research

Accepted on 16 Dec 2025

A Novel Non-Invasive Diagnostic Approach Based on Urine and Blood: A Cross-Sectional Study Combining lipoarabinomannan Antigen and interferon-gamma release assay for Active tuberculosis

in Microbial Immunology

Long Cai
Mingzhi Zhu
Tingting Fang
Qianqian Peng
Linshan Dai
Yanqin Shao
Libin Liu

Frontiers in Immunology

Correction

Accepted on 16 Dec 2025

Targeting ferroptosis: novel therapeutic approaches and intervention strategies for kidney diseases

in Inflammation

Yanfang Luo
Muyang Long
Xueqin Wu
Liuting Zeng

Frontiers in Immunology

106 views

Correction

Accepted on 16 Dec 2025

Correction: Case Report: Fecal Microbiota Transplantation via capsules ameliorated clinical outcomes in a patient with Multiple Sclerosis

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Luca Masucci
Stefano Bibbò
Flavio De Maio
Fioravante Capone
Gianluca Quaranta
Debora Rondinella
Roberto Rosato
Mauro Minelli
Desy De Lorenzis
MAURIZIO SANGUINETTI

Frontiers in Immunology

Review

Accepted on 16 Dec 2025

Fibroblast–Immune Crosstalk in Oral Squamous Cell Carcinoma: From Tumor Promotion to Immune Evasion

in Cancer Immunity and Immunotherapy

Xiao Liu
Dandan Wang
Xue Cheng
Yining Ma
Siya Li
Jinhai Deng
Chunyan Qiao

Frontiers in Immunology

Case Report

Accepted on 16 Dec 2025

Sequential Anlotinib and Camrelizumab Combination Therapy Achieves Exceptional Survival in Multi-Driver Mutated, TMB-Low/PD-L1-Low/MSS Pulmonary Sarcomatoid Carcinoma: Case Report and Literature Review

in Cancer Immunity and Immunotherapy

Jun Zhu
Ai Zhu
Li Gang
Lidong Liu
Zi-Ran Gao
Jiayun Liu
Yunfei Ye
Xunzhi Zhu
Yi Li
Hong Chen

Frontiers in Immunology

Review

Accepted on 16 Dec 2025

SLC30 (ZnT) and SLC39 (ZIP) zinc transporter families: From gatekeepers of zinc homeostasis to promoters of tumorigenesis and targets for clinical therapy

in Cancer Immunity and Immunotherapy

Yuqiao Zhou
Guangfa Huang
Mengling Liu
Minghui Zhang
Bowen Wu
Jinke Gu

Frontiers in Immunology

Study Protocol

Accepted on 16 Dec 2025

XELOX Combined With Sintilimab and Hyperbaric Oxygen Therapy for Advanced or Metastatic Gastric/Gastroesophageal Junction Adenocarcinoma: Study Protocol for a Prospective, Single-Arm, Phase Ib/II Clinical Trial

in Cancer Immunity and Immunotherapy

Wenke Li
Pengfei Zhang
Mo Cheng
Wei Jing
Menghui Xu
Dan Li
Sihui Song
Ming Liu
Cheng Huang
Lin Zhu

Frontiers in Immunology

Review

Accepted on 16 Dec 2025

From Innate-Like to Innate: The Next Wave of Off-the-Shelf CAR Immunotherapies

in Cancer Immunity and Immunotherapy

Ying Feng
Zhibo Yang
Yueru Zhou
Ying Liang
Hai Zhao

Frontiers in Immunology

Review

Accepted on 16 Dec 2025

The Immunobiology and Therapeutic potential of Regulatory T Cells in Autoimmune Diseases and Allergic Diseases

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Hao-Tao ZENG
Wen-Wen XIE
Jian-Bin HUANG
Yi-Chi ZHOU
Jing-Yi YUAN
Jia-Xue FENG
Xiaohang Shi
Li Tian
Xian-Hai ZENG
Shu-Qi QIU

Frontiers in Immunology

48,414 articles

articles

Induction of trained immunity in myeloid cells and their progenitors from thyroid cancer patients

Research progress on recombinant NDV in cancer therapy

Beyond monoclonal antibodies: constraints and the case for alternative PD-1/PD-L1-targeting formats

Dynamic genetic regulation of CD4+ T cells in obstructive sleep apnea: integrating context-specific eQTL, Mendelian randomization, single-cell sequencing, and experimental validation

OmniNeo: a multi-omics pipeline incorporating proteomics and AI selection for neoantigen optimization in tumor immunotherapy

A comparative study of large-vessel and small-vessel primary angiitis of the central nervous system: insights from a Chinese single-center retrospective cohort

COVID-19 vaccination induces cross-reactive dengue virus antibodies with altered isotype profiles and in vitro antibody-dependent enhancement

The gut microbiota composition is shaped by disease activity and individual treatment responses in patients with multiple sclerosis

The Infection–Microbiome–Immunity Axis in Bladder Cancer: Mechanistic Insights and Therapeutic Perspectives

Enhancing Named Entity Recognition for Immunology and Immune-Mediated Disorders

Correction: Antibodies and cryptographic hash functions: quantifying the specificity paradox

Editorial: Molecular Mechanisms of the Host Immune Response to Toxoplasma gondii Infection

C-X-C motif chemokine ligand 13 suppresses osteoclast differentiation via interference with RANKL–RANK interaction

Vancomycin is a risk factor for acute pancreatitis and increases the mortality rate in patients with severe pancreatitis

Aberrant B Cell Responses as Drivers of Autoantibody Generation and Epitope Diversification in SLE Pathogenesis

A Novel Non-Invasive Diagnostic Approach Based on Urine and Blood: A Cross-Sectional Study Combining lipoarabinomannan Antigen and interferon-gamma release assay for Active tuberculosis

Targeting ferroptosis: novel therapeutic approaches and intervention strategies for kidney diseases

Correction: Case Report: Fecal Microbiota Transplantation via capsules ameliorated clinical outcomes in a patient with Multiple Sclerosis

Fibroblast–Immune Crosstalk in Oral Squamous Cell Carcinoma: From Tumor Promotion to Immune Evasion

Sequential Anlotinib and Camrelizumab Combination Therapy Achieves Exceptional Survival in Multi-Driver Mutated, TMB-Low/PD-L1-Low/MSS Pulmonary Sarcomatoid Carcinoma: Case Report and Literature Review

SLC30 (ZnT) and SLC39 (ZIP) zinc transporter families: From gatekeepers of zinc homeostasis to promoters of tumorigenesis and targets for clinical therapy

XELOX Combined With Sintilimab and Hyperbaric Oxygen Therapy for Advanced or Metastatic Gastric/Gastroesophageal Junction Adenocarcinoma: Study Protocol for a Prospective, Single-Arm, Phase Ib/II Clinical Trial

From Innate-Like to Innate: The Next Wave of Off-the-Shelf CAR Immunotherapies

The Immunobiology and Therapeutic potential of Regulatory T Cells in Autoimmune Diseases and Allergic Diseases