Frontiers in Immunology

Mini Review

Published on 17 Dec 2025

Targeting glioma-associated microglia and macrophages: a new frontier in glioblastoma immunotherapy

in Cancer Immunity and Immunotherapy

Bingyang Wang
Cong Li
Jiatong Gu
Xiaojie Wang
Mingjuan Xun
Bin Jiang
Jun Yan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1726440

517 views

Perspective

Published on 17 Dec 2025

Microbiota and antibiotic exposure in sarcoidosis

in Microbial Immunology

Claudio Ucciferri
Livia Moffa
Claudio Tana

Frontiers in Immunology

doi 10.3389/fimmu.2025.1737273

190 views

Mini Review

Published on 17 Dec 2025

Mapping immune trajectories from Helicobacter pylori gastritis to gastric cancer

in Inflammation

Yi Song
Jie Qiu
Jingyue Wu
Wenqi Liu
Qiang Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1693004

325 views

Case Report

Published on 17 Dec 2025

Case Report: Novel variants in the MYD88 gene (c.104T>C, c.141G>C) in a patient with recurrent abscesses as a cause of type 68 immunodeficiency

in Primary Immunodeficiencies

Anastasiia A. Buianova
Artem A. Ivanov
Vera A. Belova
Alina F. Samitova
Tatiana V. Kulichenko
Iuliia A. Vasiliadis
Dmitriy O. Korostin
Yulia S. Lashkova

Frontiers in Immunology

doi 10.3389/fimmu.2025.1683892

360 views

Original Research

Published on 17 Dec 2025

Commiphora myrrha extract protects pigeons from Eimeria labbeana-like-triggered inflammatory dysregulation

in Parasite Immunology

Rewaida Abdel-Gaber
Shurug Albasyouni
Simeon Santourlidis
Saleh Al Quraishy
Esam Al-Shaebi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1714313

389 views

Review

Published on 17 Dec 2025

Remodeling the tumor microenvironment: regulatory effects of β-sitosterol and luteolin on the immunosuppressive milieu in endometrial carcinoma and implications for combinatorial immunotherapy

in Cancer Immunity and Immunotherapy

Guojie Ji
Pengbo Wang
Zhihong Kong
Xiangxiang Cao
Xiaowei Shi
Huigen Feng
Huanhuan Hu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1669606

232 views

Original Research

Published on 17 Dec 2025

ATF4 promotes renal tubulointerstitial fibrosis through hexokinase II-mediated glycolysis

in Inflammation

Songtao Feng
Yueming Gao
Zheng Wang
Weijie Ni
Yan Zhou
Mingyue Yuan
Jinyang Ge
Lu Sun
Bicheng Liu
Hui Qian

Frontiers in Immunology

doi 10.3389/fimmu.2025.1683249

343 views

Perspective

Published on 17 Dec 2025

Are they eosinophil extracellular traps?

in Inflammation

Pedro Chacón
Adrián López-Postigo
Javier Monteseirín
David Ribas-Pérez
Antonio Vega-Rioja

Frontiers in Immunology

doi 10.3389/fimmu.2025.1686316

135 views

Original Research

Published on 17 Dec 2025

Integrated bioinformatics and machine learning reveal pan-apoptosis and immune infiltration signatures in diabetic nephropathy

in Comparative Immunology

Yu Liu
Wenqian Lu
Zhicong Xiang
Yuli Shen
Baoyi Ni
Hequn Zou
Xiaofei Shao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1659065

316 views

Review

Published on 17 Dec 2025

Getting into host’s skin: initial immune response to Schistosoma mansoni infection

in Parasite Immunology

Carolina Melo Orrico-Ferreira
Paulo Emilio Oliveira Cruz
Joao Vitor Borges Rios
Wellington da Silva Rosa
Beatriz de Souza Santos
Raphael Chagas Silva
Carina Silva Pinheiro
Barbara Castro-Pimentel Figueiredo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1661465

395 views

Mini Review

Published on 17 Dec 2025

Perioperative immunotherapy in gastric cancer: walking a fine line between hope and caution

in Cancer Immunity and Immunotherapy

Xianlei Cai
Xia Xiao
Congcong Zhang
Weiming Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1722749

387 views

Review

Published on 17 Dec 2025

Macrophage-driven immunopathology in pulmonary arterial hypertension: from mechanisms to targeted therapies

in Inflammation

Wenna Xu
Yunlong Shen
Zhengdong Wan
Jiawei Guo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1721071

131 views

Review

Published on 17 Dec 2025

Human papillomavirus infection and vaccination with thyroid diseases: mechanistic links and immunological insights

in Viral Immunology

Zhengda Wang
Xiwen Chang
Xianbin Cheng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1732358

166 views

Case Report

Published on 17 Dec 2025

Management of alemtuzumab-induced Graves’ disease in pregnancy: a case report and literature review

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Marsida Teliti
Maria Gallo
Pietro Costa
Spyridon Chytiris
Flavia Magri
Mario Rotondi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1722459

198 views

Case Report

Published on 17 Dec 2025

Lymphocyte dynamics as the central mediator in osimertinib-induced CD4+ T-cell depletion, fulminant cytomegalovirus pneumonitis, and progressive pulmonary fibrosis: a case report

in Inflammation

Liya Zhu
Dan Liu
Jie Peng
Jinzhi Lu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1702074

263 views

Original Research

Published on 17 Dec 2025

Dual checkpoint blockade of PD-1 and Tim-3 by engineered hybrid nanovesicles for enhanced cancer immunotherapy

in Cancer Immunity and Immunotherapy

Han Xue
Longxue Guan
Lili Huang
Yuxin Fan
Fenglin Guo
Dandan Liang
Xingang Guan
Guofu Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1705438

257 views

Case Report

Published on 17 Dec 2025

Case Report: Ivonescimab in EGFR-mutant lung cancer with baseline malignant pleural effusion and acquired complex resistance

in Cancer Immunity and Immunotherapy

Zeming Mo
Honglian Jiang
Lei Zhou
Qiaoya Ren
Gang Shen
Lie Li
Xiaobin Jian
Hua Yang
Yuju Bai
Mi Meng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1725067

257 views

Correction

Published on 17 Dec 2025

Correction: Coexistence of bullous pemphigoid, intrahepatic cholangiocarcinoma, and alopecia areata: a case report of multifactorial autoimmunity in a surgical context

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Shanlin Li
Ying Wang
Dingquan Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1765423

306 views

Original Research

Published on 17 Dec 2025

Chronic opioid use is associated with higher antibody response to influenza vaccination in people living with HIV

in Vaccines and Molecular Therapeutics

Christine M. Dang
C. Mindy Nelson
Rajendra N. Pahwa
Hansel E. Tookes
Daniel J. Feaster
Prabhsimran Singh
Allan E. Rodriguez
David W. Forrest
Nobuyo Nakamura
Priya P. Ghanta

Frontiers in Immunology

doi 10.3389/fimmu.2025.1686103

358 views

Original Research

Published on 17 Dec 2025

Lactate attenuates PANoptosis and enhances ZBP-1 lactylation in macrophages in acute lung injury

in Inflammation

Dan Wang
Yi Gong
Yehao Chen
Zhefan Wang
Jinxiang Yin
Zhengrui Wang
Xiao Yang
Yizhou Zhang
Jie Huang
Zhengyu Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1648303

330 views

Original Research

Published on 17 Dec 2025

Bioinformatic and experimental identification and characterization of Clostridioides difficile lipoproteins as potential vaccine candidates

in Vaccines and Molecular Therapeutics

Soumyadeep Chakraborty
Joshua Heuler
Shaohui Wang
Junling Qin
Adrit Roy
Lubem Nathanel Agbendeh
Anastasia Tomatsidou
Hyeun Bum Kim
Xingmin Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1650364

232 views

Original Research

Published on 17 Dec 2025

Real-world effectiveness of vedolizumab in refractory pouchitis: a focus on biomarker changes during intravenous to subcutaneous transition (POUCHIVED study)

in Inflammation

Leticia Gimeno-Pitarch
Elena Céspedes-Martínez
Rocío Ferreiro-Iglesias
María Dolores Martín-Arranz
Beatriz Sicilia
Inma Lorca
José Huguet
Francisco Mesonero
Raquel Vicente-Lidón
Alejandro Mínguez

Frontiers in Immunology

doi 10.3389/fimmu.2025.1630678

283 views

Original Research

Published on 17 Dec 2025

MGAT1 knockout in human dendritic cells enhance CD8+ T cell activation

in Antigen Presenting Cell Biology

Anne Louise Blomberg
Betina Lyngfeldt Henriksen
Weihua Tian
Kerstin Skovgaard
Sarah Line Skovbakke
Steffen Goletz

Frontiers in Immunology

doi 10.3389/fimmu.2025.1588795

410 views

Original Research

Published on 17 Dec 2025

OmniNeo: a multi-omics pipeline incorporating proteomics and AI selection for neoantigen optimization in tumor immunotherapy

in Vaccines and Molecular Therapeutics

Manman Lu
Yang Liu
Linfeng Xu
Yuan Gao
Peng Liu
Zhenhao Liu
Xiaoxiu Tan
Wenzhen Li
Yong Lin
Lanming Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1727642

330 views

48,439 articles

articles

Targeting glioma-associated microglia and macrophages: a new frontier in glioblastoma immunotherapy

Microbiota and antibiotic exposure in sarcoidosis

Mapping immune trajectories from Helicobacter pylori gastritis to gastric cancer

Case Report: Novel variants in the MYD88 gene (c.104T>C, c.141G>C) in a patient with recurrent abscesses as a cause of type 68 immunodeficiency

Commiphora myrrha extract protects pigeons from Eimeria labbeana-like-triggered inflammatory dysregulation

Remodeling the tumor microenvironment: regulatory effects of β-sitosterol and luteolin on the immunosuppressive milieu in endometrial carcinoma and implications for combinatorial immunotherapy

ATF4 promotes renal tubulointerstitial fibrosis through hexokinase II-mediated glycolysis

Are they eosinophil extracellular traps?

Integrated bioinformatics and machine learning reveal pan-apoptosis and immune infiltration signatures in diabetic nephropathy

Getting into host’s skin: initial immune response to Schistosoma mansoni infection

Perioperative immunotherapy in gastric cancer: walking a fine line between hope and caution

Macrophage-driven immunopathology in pulmonary arterial hypertension: from mechanisms to targeted therapies

Human papillomavirus infection and vaccination with thyroid diseases: mechanistic links and immunological insights

Management of alemtuzumab-induced Graves’ disease in pregnancy: a case report and literature review

Lymphocyte dynamics as the central mediator in osimertinib-induced CD4+ T-cell depletion, fulminant cytomegalovirus pneumonitis, and progressive pulmonary fibrosis: a case report

Dual checkpoint blockade of PD-1 and Tim-3 by engineered hybrid nanovesicles for enhanced cancer immunotherapy

Case Report: Ivonescimab in EGFR-mutant lung cancer with baseline malignant pleural effusion and acquired complex resistance

Correction: Coexistence of bullous pemphigoid, intrahepatic cholangiocarcinoma, and alopecia areata: a case report of multifactorial autoimmunity in a surgical context

Chronic opioid use is associated with higher antibody response to influenza vaccination in people living with HIV

Lactate attenuates PANoptosis and enhances ZBP-1 lactylation in macrophages in acute lung injury

Bioinformatic and experimental identification and characterization of Clostridioides difficile lipoproteins as potential vaccine candidates

Real-world effectiveness of vedolizumab in refractory pouchitis: a focus on biomarker changes during intravenous to subcutaneous transition (POUCHIVED study)

MGAT1 knockout in human dendritic cells enhance CD8+ T cell activation

OmniNeo: a multi-omics pipeline incorporating proteomics and AI selection for neoantigen optimization in tumor immunotherapy