Frontiers in Immunology

Original Research

Published on 31 Mar 2025

Bivalent circular RNA vaccines against porcine epidemic diarrhea virus and transmissible gastroenteritis virus

in Vaccines and Molecular Therapeutics

Weibing Zhang
Lei Wang
Liyu Chu
Xu Ma
Wenjing Gao
Yarong Wu
Yongfeng Qiao
Xianjun Wang
Lu Zhao
Hong Hu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1562865

1,798 views

Case Report

Published on 31 Mar 2025

Successful treatment of primary refractory DLBCL/HGBL - MYC/BCL2 transformed from FL using glofitamab: a case report

in Cancer Immunity and Immunotherapy

Ming-qiang Chu
Ting-juan Zhang
Yuan Feng
Xun Shao
Yong-hui Ji
Jun Qian
Jing-dong Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1566035

1,594 views
1 citation

Original Research

Published on 31 Mar 2025

CD121b-positive neutrophils predict immunosuppression in septic shock

in Inflammation

Jian Chen
Jinghe Zhang
Siao Chen
Jingkun Qin
Xinyu Hu
Shengdi Xi
Lin Zhang
Min Zhou
Yonggang Zhou
Binqing Fu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1565797

1,266 views

Original Research

Published on 31 Mar 2025

The dual role of CXCL9/SPP1 polarized tumor-associated macrophages in modulating anti-tumor immunity in hepatocellular carcinoma

in Cancer Immunity and Immunotherapy

Yu Gu
Zhihui Zhang
Hao Huang
Wenyong Zhu
Hongjia Liu
Rongxin Zhang
Nan Weng
Xiao Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1528103

2,870 views

Original Research

Published on 31 Mar 2025

A weakly supervised deep learning framework for automated PD-L1 expression analysis in lung cancer

in Cancer Immunity and Immunotherapy

Feng Jiao
Zhanxian Shang
Hongmin Lu
Peilin Chen
Shiting Chen
Jiayi Xiao
Fuchuang Zhang
Dadong Zhang
Chunxin Lv
Yuchen Han

Frontiers in Immunology

doi 10.3389/fimmu.2025.1540087

1,213 views

Original Research

Published on 31 Mar 2025

Design and development of highly conserved, HLA-promiscuous T cell multiepitope vaccines against human visceral leishmaniasis

in Vaccines and Molecular Therapeutics

Aline Silva Barreto
Mariana Nobre Farias de Franca
Tatiana Leão dos Santos dos Reis
Joao Antonio Barbosa Martins Silva
Priscila Lima Dos Santos
Fabrícia Alvisi de Oliveira
Angela Maria da Silva
Lucas Sousa Magalhaes
Danielle Angst Secco
Maria Aiza Fontes Andrade

Frontiers in Immunology

doi 10.3389/fimmu.2025.1540537

1,320 views

Original Research

Published on 31 Mar 2025

Keloids and inflammation: the crucial role of IL-33 in epidermal changes

in Inflammation

ZongAn Chen
YaTing Yang
XiuXia Wang
LingLing Xia
WenBo Wang
XiaoLi Wu
Zhen Gao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1514618

1,310 views

Original Research

Published on 31 Mar 2025

Platelet secretions exert anti-inflammatory effects in vitro on neutrophils and uterine epithelia in cattle: a possible role in amplifying the uterine immune network toward pregnancy

in Comparative Immunology

Mohamed Samy Yousef
Ihshan Akthar
Dongxue Ma
Shingo Haneda
Kazuya Kusama
Masayuki Shimada
Kazuhiko Imakawa
Akio Miyamoto

Frontiers in Immunology

doi 10.3389/fimmu.2025.1560996

1,065 views

Original Research

Published on 31 Mar 2025

Impact of single nucleotide polymorphisms of immunomodulatory factors on treatment response and prognosis in acute myeloid leukemia

in Cancer Immunity and Immunotherapy

Mingying Li
Tao Sun
Mengyuan Chang
Tingting Liu
Lei Feng
Di Zhang
Yuyan Wu
Yuechan Ma
Huixian Ma
Guangqiang Meng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1571332

1,049 views

Original Research

Published on 31 Mar 2025

Efficacy and safety of immune checkpoint inhibitors in advanced biliary tract cancer: a real-world study

in Cancer Immunity and Immunotherapy

Yichen Zheng
Jiamin Guo
Tonghui Ren
Ji Ma
Dan Cao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1493234

1,380 views

Original Research

Published on 31 Mar 2025

Development of a refined experimental mouse model of myasthenia gravis with anti-acetylcholine receptor antibodies

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Axel You
Léa S. Lippens
Odessa-Maud Fayet
Solène Maillard
Laureline Betemps
Antony Grondin
Jean-Thomas Vilquin
Nadine Dragin
Rozen Le Panse

Frontiers in Immunology

doi 10.3389/fimmu.2025.1521382

2,021 views

Original Research

Published on 31 Mar 2025

IFN-γ-Induced intestinal epithelial cell-type-specific programmed cell death: PANoptosis and its modulation in Crohn’s disease

in Mucosal Immunity

Chansu Lee
Ji Eun Kim
Yeo-Eun Cha
Ji Hwan Moon
Eun Ran Kim
Dong Kyung Chang
Young-Ho Kim
Sung Noh Hong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1523984

1,954 views

Mini Review

Published on 31 Mar 2025

The role of polysaccharides in immune regulation through gut microbiota: mechanisms and implications

in Cytokines and Soluble Mediators in Immunity

Ting Zhao
Congyue Wang
Yuhan Liu
Bo Li
Mingjia Shao
Wuyang Zhao
Chuang Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1555414

1,432 views
1 citation

Mini Review

Published on 31 Mar 2025

PI3K/Akt in IPF: untangling fibrosis and charting therapies

in Inflammation

Janki Bhatt
Alessandra Ghigo
Emilio Hirsch

Frontiers in Immunology

doi 10.3389/fimmu.2025.1549277

2,319 views

Original Research

Published on 31 Mar 2025

The type of pathogen is associated with organ failure and legacy dysfunction in patients with sepsis

in Microbial Immunology

Qinfen Gao
Zengzheng Li
Jiawei Geng
Bin Han
Tonghua Yang
Shuai Feng
Lijuan Zhao
Yajun Teng
Yafei Li
Renbin Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1541634

1,170 views

Original Research

Published on 31 Mar 2025

ESCRT may function as a tumor biomarker, transitioning from pan-cancer analysis to validation within breast cancer

in Cancer Immunity and Immunotherapy

Xiao-rui Chen
Xue-ying Tan
Zong-liang Zhang
Jiang-shui Yuan
Wei-qing Song

Frontiers in Immunology

doi 10.3389/fimmu.2025.1531940

2,206 views