Frontiers in Immunology | Cytokines and Soluble Mediators in Immunity

Editorial

Published on 26 Mar 2025

Editorial: SOCS: regulation of the immune system at a whole new level

in Cytokines and Soluble Mediators in Immunity

Sandra E. Nicholson
Chulbul M. Ahmed
Karen Doggett
Daniela Marasco
Howard M. Johnson

Frontiers in Immunology

doi 10.3389/fimmu.2025.1588549

1,743 views

Original Research

Published on 24 Mar 2025

Discovery of KDM5D as a novel biomarker for traumatic brain injury identified through bioinformatics analysis

in Cytokines and Soluble Mediators in Immunity

Dengfeng Ding
Mengzhe Yang
Xinou Zheng
Ming Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1538561

4,495 views

Original Research

Published on 24 Mar 2025

Cytokine interactions and chemokine dysregulations in mastitis immunopathogenesis: insights from transcriptomic profiling of milk somatic cells in tropical Sahiwal (Bos indicus) cows

in Cytokines and Soluble Mediators in Immunity

Lija Satheesan
Ajay Kumar Dang
Rani Alex

Frontiers in Immunology

doi 10.3389/fimmu.2025.1554341

2,364 views
1 citation

Mini Review

Published on 21 Mar 2025

Chemokines as therapeutic targets for multiple sclerosis: a spatial and chronological perspective

in Cytokines and Soluble Mediators in Immunity

Nagisa Nakata Arimitsu
Alicja Witkowska
Ayaka Ohashi
Chie Miyabe
Yoshishige Miyabe

Frontiers in Immunology

doi 10.3389/fimmu.2025.1547256

3,932 views
2 citations

Review

Published on 17 Mar 2025

From death to birth: how osteocyte death promotes osteoclast formation

in Cytokines and Soluble Mediators in Immunity

Weijie Zhao
Jiale Qian
Ji Li
Tian Su
Xiaozhong Deng
Yonghua Fu
Xuelong Liang
Hongwang Cui

Frontiers in Immunology

doi 10.3389/fimmu.2025.1551542

5,912 views
12 citations

Opinion

Published on 17 Mar 2025

Combining immune checkpoints with TNFSF agonists: a new horizon for cancer and autoimmune therapies

in Cytokines and Soluble Mediators in Immunity

Lele Sun
Cuiping Li
Tingting Gao
Zhe Liu
Yanli Hou
Wei Han

Frontiers in Immunology

doi 10.3389/fimmu.2025.1557176

1,674 views
1 citation

Review

Published on 17 Mar 2025

Healthy and premature aging of monocytes and macrophages

in Cytokines and Soluble Mediators in Immunity

Syamantak Basu
Ying Ulbricht
Manuela Rossol

Frontiers in Immunology

doi 10.3389/fimmu.2025.1506165

6,642 views
9 citations

Original Research

Published on 12 Mar 2025

Guselkumab binding to CD64+ IL-23–producing myeloid cells enhances potency for neutralizing IL-23 signaling

in Cytokines and Soluble Mediators in Immunity

Kacey L. Sachen
Deepa Hammaker
Indra Sarabia
Brian Stoveken
John Hartman
Kristin L. Leppard
Nicholas A. Manieri
Phuc Bao
Carrie Greving
Eilyn R. Lacy

Frontiers in Immunology

doi 10.3389/fimmu.2025.1532852

19,216 views
16 citations

Editorial

Published on 12 Mar 2025

Editorial: Adenine nucleotides in immunity and inflammation

in Cytokines and Soluble Mediators in Immunity

Christa E. Müller
Santina Bruzzone
Andreas H. Guse

Frontiers in Immunology

doi 10.3389/fimmu.2025.1585484

1,681 views
1 citation

Original Research

Published on 07 Mar 2025

Designing a CXCL8-hsa chimera as potential immunmodulator of the tumor micro-environment

in Cytokines and Soluble Mediators in Immunity

Tanja Gerlza
Christina Trojacher
Thomas Fuchs
Aid Atlic
Roland Weis
Tiziana Adage
Andreas J. Kungl

Frontiers in Immunology

doi 10.3389/fimmu.2025.1539733

2,731 views

Review

Published on 28 Feb 2025

T cells in the microenvironment of solid pediatric tumors: the case of neuroblastoma

in Cytokines and Soluble Mediators in Immunity

Enrico Maggi
Nadine Landolina
Enrico Munari
Francesca Romana Mariotti
Nicola Tumino
Paola Vacca
Bruno Azzarone
Lorenzo Moretta

Frontiers in Immunology

doi 10.3389/fimmu.2025.1544137

3,716 views
1 citation

Correction

Published on 27 Feb 2025

Corrigendum: SARS-CoV2 infection during pregnancy causes persistent immune abnormalities in women without affecting the newborns

in Cytokines and Soluble Mediators in Immunity

Elena Vazquez-Alejo
Laura Tarancon-Diez
Itzíar Carrasco
Sara Vigil-Vázquez
Mar Muñoz-Chapuli
Elena Rincón-López
Jesús Saavedra-Lozano
Mar Santos-Sebastián
David Aguilera-Alonso
Alicia Hernanz-Lobo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1574788

1,137 views

Original Research

Published on 20 Feb 2025

Interaction between nasal epithelial cells and Tregs in allergic rhinitis responses to allergen via CCL1/CCR8

in Cytokines and Soluble Mediators in Immunity

Jichao Sha
Maolin Yang
Yashu Lei
Liwei Sun
Cuida Meng
Dongdong Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1526081

4,021 views
3 citations

Original Research

Published on 13 Feb 2025

Elevated levels of IRF1 and CASP1 as pyroptosis-related biomarkers for intestinal epithelial cells in Crohn’s disease

in Cytokines and Soluble Mediators in Immunity

Xiaofang Xu
Xiaodan Lv
Ruizhi Zeng
Zhixi Huang
Ziqian Huang
Bing Han
Guangfu Lin
Jianing Lin
Shiquan Li
Junhua Fan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1551547

4,703 views
4 citations

Editorial

Published on 11 Feb 2025

Editorial: Unraveling the molecular mechanisms of cytokine signaling in regulating inflammatory diseases

in Cytokines and Soluble Mediators in Immunity

Jian Zheng
Huawei Mao
Wai Po Chong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1563469

2,145 views
2 citations

Original Research

Published on 10 Feb 2025

Cerebrospinal fluid and serum cytokine profiles in severe viral encephalitis with implications for refractory status epilepticus: a retrospective observational study

in Cytokines and Soluble Mediators in Immunity

Peipei Huang
Fan Yang
Ruirui Dong
Lijun Wen
Qiuling Zang
Dandan Song
Junshuang Guo
Yating Wang
Ruike Zhang
Zhiping Ren

Frontiers in Immunology

doi 10.3389/fimmu.2025.1528763

2,360 views
1 citation

Original Research

Published on 10 Feb 2025

CD38 deficiency leads to a defective short-lived transcriptomic response to chronic graft-versus-host disease induction, involving purinergic signaling-related genes and distinct transcriptomic signatures associated with lupus

in Cytokines and Soluble Mediators in Immunity

Mercedes Zubiaur
Laura C. Terrón-Camero
Fernando Gordillo-González
Eduardo Andrés-León
Alicia Barroso-del Jesús
Luz María Canet-Antequera
María M. Pérez Sánchez-Cañete
África Martínez-Blanco
Marilú Domínguez-Pantoja
María Botia-Sánchez

Frontiers in Immunology

doi 10.3389/fimmu.2025.1441981

4,580 views

Original Research

Published on 06 Feb 2025

Candidate approaches for predicting vitiligo recurrence: an effective model and biomarkers

in Cytokines and Soluble Mediators in Immunity

Binhao Liu
Jiacheng Shen
Jiayu Li
Bowen Tian
Bin Zhou
Jiachen Gui
Zhimin Li
Yue Zhang
Wenzhi Hu
Qiang Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1468665

4,112 views
6 citations

Review

Published on 04 Feb 2025

Pathogenic and therapeutic roles of extracellular vesicles in sepsis

in Cytokines and Soluble Mediators in Immunity

Benshuai You
Yang Yang
Jing Wei
Chenglin Zhou
Surong Dong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1535427

4,231 views
2 citations

Case Report

Published on 04 Feb 2025

Case report: Exploring efficacy of tofacitinib in modulating interferon response in five case of anti-MDA5+ dermatomyositis with interstitial lung disease

in Cytokines and Soluble Mediators in Immunity

Jie Zhao
Yan Bao
Ying Gao
Keliang Xie

Frontiers in Immunology

doi 10.3389/fimmu.2025.1515602

3,914 views

Review

Published on 31 Jan 2025

Based on the immune system: the role of the IL-2 family in pancreatic disease

in Cytokines and Soluble Mediators in Immunity

Yuqing Zhu
Zheng Lu
Zhuo Wang
Jiao Liu
Ke Ning

Frontiers in Immunology

doi 10.3389/fimmu.2025.1480496

4,050 views
2 citations

Case Report

Published on 28 Jan 2025

Case report: Therapeutic use of bortezomib in a patient with Schnitzler syndrome

in Cytokines and Soluble Mediators in Immunity

Hua Bai
Dongming Zhou
Jinwen Liu
Jie He
Zhou Min
Wenyong Fan
Bing Chen
Yong Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1520470

2,258 views
4 citations

Original Research

Published on 28 Jan 2025

Comprehensive analysis of Pan-Immune Inflammation and all-cause mortality in rheumatoid arthritis: a database-driven approach, 1999-2018

in Cytokines and Soluble Mediators in Immunity

Muradil· Mardan
Huoliang Zheng
Qingyin Xu
Shaokuan Song
Zeyu Lu
Hui Deng
Hao Cai
Qizhu Chen
Bingyi Yang
Kudelaiti· Abuduwufuer

Frontiers in Immunology

doi 10.3389/fimmu.2025.1549955

5,676 views
12 citations

Review

Published on 24 Jan 2025

IL-33/ST2 axis in diverse diseases: regulatory mechanisms and therapeutic potential

in Cytokines and Soluble Mediators in Immunity

Feiya Sheng
Mi Li
Jia-Mei Yu
Si-Yu Yang
Liang Zou
Guan-Jun Yang
Le-Le Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1533335

8,969 views
17 citations

1,282 articles

articles

Editorial: SOCS: regulation of the immune system at a whole new level

Discovery of KDM5D as a novel biomarker for traumatic brain injury identified through bioinformatics analysis

Cytokine interactions and chemokine dysregulations in mastitis immunopathogenesis: insights from transcriptomic profiling of milk somatic cells in tropical Sahiwal (Bos indicus) cows

Chemokines as therapeutic targets for multiple sclerosis: a spatial and chronological perspective

From death to birth: how osteocyte death promotes osteoclast formation

Combining immune checkpoints with TNFSF agonists: a new horizon for cancer and autoimmune therapies

Healthy and premature aging of monocytes and macrophages

Guselkumab binding to CD64+ IL-23–producing myeloid cells enhances potency for neutralizing IL-23 signaling

Editorial: Adenine nucleotides in immunity and inflammation

Designing a CXCL8-hsa chimera as potential immunmodulator of the tumor micro-environment

T cells in the microenvironment of solid pediatric tumors: the case of neuroblastoma

Corrigendum: SARS-CoV2 infection during pregnancy causes persistent immune abnormalities in women without affecting the newborns

Interaction between nasal epithelial cells and Tregs in allergic rhinitis responses to allergen via CCL1/CCR8

Elevated levels of IRF1 and CASP1 as pyroptosis-related biomarkers for intestinal epithelial cells in Crohn’s disease

Editorial: Unraveling the molecular mechanisms of cytokine signaling in regulating inflammatory diseases

Cerebrospinal fluid and serum cytokine profiles in severe viral encephalitis with implications for refractory status epilepticus: a retrospective observational study

CD38 deficiency leads to a defective short-lived transcriptomic response to chronic graft-versus-host disease induction, involving purinergic signaling-related genes and distinct transcriptomic signatures associated with lupus

Candidate approaches for predicting vitiligo recurrence: an effective model and biomarkers

Pathogenic and therapeutic roles of extracellular vesicles in sepsis

Case report: Exploring efficacy of tofacitinib in modulating interferon response in five case of anti-MDA5+ dermatomyositis with interstitial lung disease

Based on the immune system: the role of the IL-2 family in pancreatic disease

Case report: Therapeutic use of bortezomib in a patient with Schnitzler syndrome

Comprehensive analysis of Pan-Immune Inflammation and all-cause mortality in rheumatoid arthritis: a database-driven approach, 1999-2018

IL-33/ST2 axis in diverse diseases: regulatory mechanisms and therapeutic potential