Frontiers in Immunology | Cytokines and Soluble Mediators in Immunity

Original Research

Published on 23 Jan 2025

The role of CTGF and MFG-E8 in the prognosis assessment of SCAP: a study combining machine learning and nomogram analysis

in Cytokines and Soluble Mediators in Immunity

Tingting Lin
Huimin Wan
Jie Ming
Yifei Liang
Linxin Ran
Jingjing Lu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1446415

3,101 views
1 citation

Original Research

Published on 15 Jan 2025

Caspase-1 activation, IL-1/IL-6 signature and IFNγ-induced chemokines in lungs of COVID-19 patients

in Cytokines and Soluble Mediators in Immunity

Audrey Cambon
Christophe Guervilly
Clémence Delteil
Nicola Potere
Richard Bachelier
Edwige Tellier
Evelyne Abdili
Marine Leprince
Marco Giani
Ildo Polidoro

Frontiers in Immunology

doi 10.3389/fimmu.2024.1493306

3,409 views
6 citations

Original Research

Published on 14 Jan 2025

Terminal complement complex deposition on chondrocytes promotes premature senescence in age- and trauma-related osteoarthritis

in Cytokines and Soluble Mediators in Immunity

Leonie Ruths
Jana Hengge
Graciosa Q. Teixeira
Melanie Haffner-Luntzer
Anita Ignatius
Jana Riegger

Frontiers in Immunology

doi 10.3389/fimmu.2024.1470907

4,168 views
1 citation

Hypothesis and Theory

Published on 13 Jan 2025

Healthy individuals genetically at-risk for the development of Pemphigus vulgaris or Alopecia areata share disease-like cytokine dysregulation

in Cytokines and Soluble Mediators in Immunity

Rebekah R. Schwartz
Kristina Seiffert-Sinha
Animesh A. Sinha

Frontiers in Immunology

doi 10.3389/fimmu.2024.1500284

1,827 views
2 citations

Review

Published on 09 Jan 2025

The role and therapeutic targeting of the CCL2/CCR2 signaling axis in inflammatory and fibrotic diseases

in Cytokines and Soluble Mediators in Immunity

Shan Guo
Qi Zhang
Yingjie Guo
Xiaoyan Yin
Peng Zhang
Tao Mao
Zibin Tian
Xiaoyu Li

Frontiers in Immunology

doi 10.3389/fimmu.2024.1497026

10,647 views
15 citations

Original Research

Published on 07 Jan 2025

Analysis of fatty acid-derived lipids in critically ill patients after cardiac surgery yields novel pathophysiologically relevant mediators with possible relevance for systemic inflammatory reactions

in Cytokines and Soluble Mediators in Immunity

Holger Neb
Verena Roth
Jessica Roos
Tom Bauer
Anja Urbschat
Ulrike Heinicke
Carlo Angioni
Dieter Steinhilber
Matthias Piesche
Nerea Ferreirós

Frontiers in Immunology

doi 10.3389/fimmu.2024.1148806

4,064 views
4 citations

Original Research

Published on 06 Jan 2025

Long-term increase in soluble interleukin-6 receptor levels in convalescents after mild COVID-19 infection

in Cytokines and Soluble Mediators in Immunity

Juliane Lokau
Yvonne Garbers
Manuel M. Vicente
Anna Dittrich
Stefan Meltendorf
Holger Lingel
Anja K. Münster-Kühnel
Monika Brunner-Weinzierl
Christoph Garbers

Frontiers in Immunology

doi 10.3389/fimmu.2024.1488745

3,321 views
7 citations

Review

Published on 03 Jan 2025

Advances in the research of immunomodulatory mechanism of mesenchymal stromal/stem cells on periodontal tissue regeneration

in Cytokines and Soluble Mediators in Immunity

De-Zhi Zhao
Rui-Lin Yang
Han-Xiao Wei
Kang Yang
Yi-Bing Yang
Nuo-Xin Wang
Qian Zhang
Fang Chen
Tao Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1449411

4,783 views
11 citations

Original Research

Published on 23 Dec 2024

Regulation of human Th9 cell differentiation by lipid modulators targeting PPAR-γ and acetyl-CoA-carboxylase 1

in Cytokines and Soluble Mediators in Immunity

Swetha Peesari
Jeremy P. McAleer

Frontiers in Immunology

doi 10.3389/fimmu.2024.1509408

2,841 views
7 citations

Original Research

Published on 18 Dec 2024

The landscape of chemokine and cytokine is associated with the distinct clinical status of leprosy patients and their respective household contacts

in Cytokines and Soluble Mediators in Immunity

Lorena Bruna Pereira de Oliveira
Pedro Henrique Ferreira Marçal
Karolina Dias Campos
Daisy Cristina Monteiro dos Santos
Marlucy Rodrigues Lima
Olindo Assis Martins-Filho
Joaquim Pedro Brito-de-Sousa
Thais Abdala-Torres
Roberta Olmo Pinheiro
Euzenir Nunes Sarno

Frontiers in Immunology

doi 10.3389/fimmu.2024.1476450

1,958 views

Original Research

Published on 18 Dec 2024

High cumulative glucocorticoid dose is associated with increased levels of inflammation-related mediators in active rheumatoid arthritis

in Cytokines and Soluble Mediators in Immunity

Anna Petrackova
Pavel Horak
Jakub Savara
Martina Skacelova
Eva Kriegova

Frontiers in Immunology

doi 10.3389/fimmu.2024.1505615

2,535 views
5 citations

Original Research

Published on 16 Dec 2024

The histamine analogue clobenpropit modulates IRF7 phosphorylation and interferon production by targeting CXCR4 in systemic lupus erythematosus models

in Cytokines and Soluble Mediators in Immunity

Nassima Bekaddour
Nikaïa Smith
Birgit Caspar
Severine Grinberg
Stephane Giorgiutti
Vincent Rodeschini
Stephanie Dupuy
Nicolas Leboulanger
Darragh Duffy
Pauline Soulas-Sprauel

Frontiers in Immunology

doi 10.3389/fimmu.2024.1490593

3,543 views
3 citations

Original Research

Published on 11 Dec 2024

PgRNA closely correlates to cytokine profile in HBeAg-positive pregnant women undergoing prophylactic antiviral intervention

in Cytokines and Soluble Mediators in Immunity

Qiao Tang
Chunrui Wang
Hu Li
Zhiwei Chen
Xiaoqing Liu
Yunling Xue
Yue Qiu
Yi Zeng
Peng Hu

Frontiers in Immunology

doi 10.3389/fimmu.2024.1511855

2,558 views
2 citations

Clinical Trial

Published on 09 Dec 2024

Evaluation of the safety, tolerability, pharmacokinetics and pharmacodynamics of SM17 in healthy volunteers: results from pre-clinical models and a first-in-human, randomized, double blinded clinical trial

in Cytokines and Soluble Mediators in Immunity

Guolin Xu
Sabina Paglialunga
Xuchen Qian
Ru Ding
Kenneth Webster
Aernout van Haarst
Caroline Engel
Chin Wai Hui
Lik Hang Lam
Weimin Li

Frontiers in Immunology

doi 10.3389/fimmu.2024.1495540

6,594 views
5 citations

Original Research

Published on 06 Dec 2024

Time-dependent variation in immunoparalysis biomarkers among patients with sepsis and critical illness

in Cytokines and Soluble Mediators in Immunity

Abigail Samuelsen
Erik Lehman
Parker Burrows
Anthony S. Bonavia

Frontiers in Immunology

doi 10.3389/fimmu.2024.1498974

2,402 views
5 citations

Original Research

Published on 04 Dec 2024

Cytokine profiling reveals HLA-linked Th2 and Th17 driven immune activation in pemphigus vulgaris patients and genetically susceptible healthy controls

in Cytokines and Soluble Mediators in Immunity

Rebekah R. Schwartz
Kristina Seiffert-Sinha
Animesh A. Sinha

Frontiers in Immunology

doi 10.3389/fimmu.2024.1500231

2,339 views
3 citations

Original Research

Published on 27 Nov 2024

Extracellular vesicles epitopes as potential biomarker candidates in patients with traumatic spinal cord injury

in Cytokines and Soluble Mediators in Immunity

Jason-Alexander Hörauf
Cora Rebecca Schindler
Inna Schaible
Minhong Wang
Birte Weber
André El Saman
Christiane Pallas
Marek Widera
Ingo Marzi
Dirk Henrich

Frontiers in Immunology

doi 10.3389/fimmu.2024.1478786

2,447 views
4 citations

Original Research

Published on 21 Nov 2024

Modulation of the hepatic RANK-RANKL-OPG axis by combined C5 and CD14 inhibition in a long-term polytrauma model

in Cytokines and Soluble Mediators in Immunity

Yang Li
Klemens Horst
Johannes Greven
Ümit Mert
Ludmila Lupu
Annette Palmer
Lena Doerfer
Qun Zhao
Xing Zhang
Rebecca Halbgebauer

Frontiers in Immunology

doi 10.3389/fimmu.2024.1434274

2,895 views
1 citation

Original Research

Published on 13 Nov 2024

Autoantibodies targeting interferons and GM-CSF are associated with adverse outcome risk, comorbidities, and pathogen in community-acquired pneumonia

in Cytokines and Soluble Mediators in Immunity

Jakob Hjorth Von Stemann
Arnold Matovu Dungu
Maria Vispe Laguarda
Camilla Koch Ryrsø
Maria Hein Hegelund
Daniel Faurholt-Jepsen
Rikke Krogh-Madsen
Morten Bagge Hansen
Birgitte Lindegaard
Sisse Rye Ostrowski

Frontiers in Immunology

doi 10.3389/fimmu.2024.1459616

2,782 views
1 citation

Original Research

Published on 07 Nov 2024

Effects of COVID-19 on bone fragility: a new perspective from osteoimmunological biomarkers

in Cytokines and Soluble Mediators in Immunity

Emanuela Galliera
Luca Massaccesi
Laura Mangiavini
Elena De Vecchi
Francesca Villa
Massimiliano Marco Corsi Romanelli
Giuseppe Peretti

Frontiers in Immunology

doi 10.3389/fimmu.2024.1493643

3,243 views
2 citations

Original Research

Published on 04 Nov 2024

Leveraging long-acting IL-15 agonists for intratumoral delivery and enhanced antimetastatic activity

in Cytokines and Soluble Mediators in Immunity

John A. Hangasky
Rocío del Valle Fernández
Dimitris Stellas
Guillermo Hails
Sevasti Karaliota
Gary W. Ashley
Barbara K. Felber
George N. Pavlakis
Daniel V. Santi

Frontiers in Immunology

doi 10.3389/fimmu.2024.1458145

3,926 views
3 citations

Original Research

Published on 29 Oct 2024

An early HMGB1 rise 12 hours before creatinine predicts acute kidney injury and multiple organ failure in a smoke inhalation and burn swine model

in Cytokines and Soluble Mediators in Immunity

Zhangsheng Yang
Tomas S. Cancio
Robert P. Willis
Matthew D. Young
Dustin M. Kneifel
Jose Salinas
Andrew D. Meyer

Frontiers in Immunology

doi 10.3389/fimmu.2024.1447597

3,553 views
2 citations

Original Research

Published on 28 Oct 2024

Delayed macrophage targeting by clodronate liposomes worsens the progression of cytokine storm syndrome

in Cytokines and Soluble Mediators in Immunity

Kunjan Khanna
Emily Eul
Hui Yan
Roberta Faccio

Frontiers in Immunology

doi 10.3389/fimmu.2024.1477449

3,503 views
1 citation

Original Research

Published on 23 Oct 2024

Enhancement of a one-step membrane technique for the treatment of large bone defects by pre-seeding the membrane with CD8 lymphocyte depleted bone marrow mononuclear cells in a rat femoral defect model

in Cytokines and Soluble Mediators in Immunity

Marissa Penna-Martinez
Andreas Kammerer
Pia Stützle
Sabatian Fees
Savina Behr
Inna Schaible
Katrin Schröder
René Danilo Verboket
Jonas Neijhoft
Ingo Marzi

Frontiers in Immunology

doi 10.3389/fimmu.2024.1488611

2,222 views
1 citation

1,282 articles

articles

The role of CTGF and MFG-E8 in the prognosis assessment of SCAP: a study combining machine learning and nomogram analysis

Caspase-1 activation, IL-1/IL-6 signature and IFNγ-induced chemokines in lungs of COVID-19 patients

Terminal complement complex deposition on chondrocytes promotes premature senescence in age- and trauma-related osteoarthritis

Healthy individuals genetically at-risk for the development of Pemphigus vulgaris or Alopecia areata share disease-like cytokine dysregulation

The role and therapeutic targeting of the CCL2/CCR2 signaling axis in inflammatory and fibrotic diseases

Analysis of fatty acid-derived lipids in critically ill patients after cardiac surgery yields novel pathophysiologically relevant mediators with possible relevance for systemic inflammatory reactions

Long-term increase in soluble interleukin-6 receptor levels in convalescents after mild COVID-19 infection

Advances in the research of immunomodulatory mechanism of mesenchymal stromal/stem cells on periodontal tissue regeneration

Regulation of human Th9 cell differentiation by lipid modulators targeting PPAR-γ and acetyl-CoA-carboxylase 1

The landscape of chemokine and cytokine is associated with the distinct clinical status of leprosy patients and their respective household contacts

High cumulative glucocorticoid dose is associated with increased levels of inflammation-related mediators in active rheumatoid arthritis

The histamine analogue clobenpropit modulates IRF7 phosphorylation and interferon production by targeting CXCR4 in systemic lupus erythematosus models

PgRNA closely correlates to cytokine profile in HBeAg-positive pregnant women undergoing prophylactic antiviral intervention

Evaluation of the safety, tolerability, pharmacokinetics and pharmacodynamics of SM17 in healthy volunteers: results from pre-clinical models and a first-in-human, randomized, double blinded clinical trial

Time-dependent variation in immunoparalysis biomarkers among patients with sepsis and critical illness

Cytokine profiling reveals HLA-linked Th2 and Th17 driven immune activation in pemphigus vulgaris patients and genetically susceptible healthy controls

Extracellular vesicles epitopes as potential biomarker candidates in patients with traumatic spinal cord injury

Modulation of the hepatic RANK-RANKL-OPG axis by combined C5 and CD14 inhibition in a long-term polytrauma model

Autoantibodies targeting interferons and GM-CSF are associated with adverse outcome risk, comorbidities, and pathogen in community-acquired pneumonia

Effects of COVID-19 on bone fragility: a new perspective from osteoimmunological biomarkers

Leveraging long-acting IL-15 agonists for intratumoral delivery and enhanced antimetastatic activity

An early HMGB1 rise 12 hours before creatinine predicts acute kidney injury and multiple organ failure in a smoke inhalation and burn swine model

Delayed macrophage targeting by clodronate liposomes worsens the progression of cytokine storm syndrome

Enhancement of a one-step membrane technique for the treatment of large bone defects by pre-seeding the membrane with CD8 lymphocyte depleted bone marrow mononuclear cells in a rat femoral defect model