Frontiers in Immunology | Cytokines and Soluble Mediators in Immunity

Original Research

Published on 13 Feb 2025

Elevated levels of IRF1 and CASP1 as pyroptosis-related biomarkers for intestinal epithelial cells in Crohn’s disease

in Cytokines and Soluble Mediators in Immunity

Xiaofang Xu
Xiaodan Lv
Ruizhi Zeng
Zhixi Huang
Ziqian Huang
Bing Han
Guangfu Lin
Jianing Lin
Shiquan Li
Junhua Fan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1551547

3,717 views

Editorial

Published on 11 Feb 2025

Editorial: Unraveling the molecular mechanisms of cytokine signaling in regulating inflammatory diseases

in Cytokines and Soluble Mediators in Immunity

Jian Zheng
Huawei Mao
Wai Po Chong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1563469

1,632 views
1 citation

Original Research

Published on 10 Feb 2025

Cerebrospinal fluid and serum cytokine profiles in severe viral encephalitis with implications for refractory status epilepticus: a retrospective observational study

in Cytokines and Soluble Mediators in Immunity

Peipei Huang
Fan Yang
Ruirui Dong
Lijun Wen
Qiuling Zang
Dandan Song
Junshuang Guo
Yating Wang
Ruike Zhang
Zhiping Ren

Frontiers in Immunology

doi 10.3389/fimmu.2025.1528763

1,737 views
1 citation

Original Research

Published on 10 Feb 2025

CD38 deficiency leads to a defective short-lived transcriptomic response to chronic graft-versus-host disease induction, involving purinergic signaling-related genes and distinct transcriptomic signatures associated with lupus

in Cytokines and Soluble Mediators in Immunity

Mercedes Zubiaur
Laura C. Terrón-Camero
Fernando Gordillo-González
Eduardo Andrés-León
Alicia Barroso-del Jesús
Luz María Canet-Antequera
María M. Pérez Sánchez-Cañete
África Martínez-Blanco
Marilú Domínguez-Pantoja
María Botia-Sánchez

Frontiers in Immunology

doi 10.3389/fimmu.2025.1441981

3,474 views

Original Research

Published on 06 Feb 2025

Candidate approaches for predicting vitiligo recurrence: an effective model and biomarkers

in Cytokines and Soluble Mediators in Immunity

Binhao Liu
Jiacheng Shen
Jiayu Li
Bowen Tian
Bin Zhou
Jiachen Gui
Zhimin Li
Yue Zhang
Wenzhi Hu
Qiang Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1468665

2,769 views
1 citation

Case Report

Published on 04 Feb 2025

Case report: Exploring efficacy of tofacitinib in modulating interferon response in five case of anti-MDA5+ dermatomyositis with interstitial lung disease

in Cytokines and Soluble Mediators in Immunity

Jie Zhao
Yan Bao
Ying Gao
Keliang Xie

Frontiers in Immunology

doi 10.3389/fimmu.2025.1515602

3,049 views

Review

Published on 04 Feb 2025

Pathogenic and therapeutic roles of extracellular vesicles in sepsis

in Cytokines and Soluble Mediators in Immunity

Benshuai You
Yang Yang
Jing Wei
Chenglin Zhou
Surong Dong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1535427

2,937 views

Review

Published on 31 Jan 2025

Based on the immune system: the role of the IL-2 family in pancreatic disease

in Cytokines and Soluble Mediators in Immunity

Yuqing Zhu
Zheng Lu
Zhuo Wang
Jiao Liu
Ke Ning

Frontiers in Immunology

doi 10.3389/fimmu.2025.1480496

3,115 views
1 citation

Case Report

Published on 28 Jan 2025

Case report: Therapeutic use of bortezomib in a patient with Schnitzler syndrome

in Cytokines and Soluble Mediators in Immunity

Hua Bai
Dongming Zhou
Jinwen Liu
Jie He
Zhou Min
Wenyong Fan
Bing Chen
Yong Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1520470

1,748 views
3 citations

Original Research

Published on 28 Jan 2025

Comprehensive analysis of Pan-Immune Inflammation and all-cause mortality in rheumatoid arthritis: a database-driven approach, 1999-2018

in Cytokines and Soluble Mediators in Immunity

Muradil· Mardan
Huoliang Zheng
Qingyin Xu
Shaokuan Song
Zeyu Lu
Hui Deng
Hao Cai
Qizhu Chen
Bingyi Yang
Kudelaiti· Abuduwufuer

Frontiers in Immunology

doi 10.3389/fimmu.2025.1549955

4,529 views
7 citations

Review

Published on 24 Jan 2025

IL-33/ST2 axis in diverse diseases: regulatory mechanisms and therapeutic potential

in Cytokines and Soluble Mediators in Immunity

Feiya Sheng
Mi Li
Jia-Mei Yu
Si-Yu Yang
Liang Zou
Guan-Jun Yang
Le-Le Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1533335

5,377 views
11 citations

Original Research

Published on 23 Jan 2025

The role of CTGF and MFG-E8 in the prognosis assessment of SCAP: a study combining machine learning and nomogram analysis

in Cytokines and Soluble Mediators in Immunity

Tingting Lin
Huimin Wan
Jie Ming
Yifei Liang
Linxin Ran
Jingjing Lu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1446415

2,380 views
1 citation

Original Research

Published on 15 Jan 2025

Caspase-1 activation, IL-1/IL-6 signature and IFNγ-induced chemokines in lungs of COVID-19 patients

in Cytokines and Soluble Mediators in Immunity

Audrey Cambon
Christophe Guervilly
Clémence Delteil
Nicola Potere
Richard Bachelier
Edwige Tellier
Evelyne Abdili
Marine Leprince
Marco Giani
Ildo Polidoro

Frontiers in Immunology

doi 10.3389/fimmu.2024.1493306

2,468 views
4 citations

Original Research

Published on 14 Jan 2025

Terminal complement complex deposition on chondrocytes promotes premature senescence in age- and trauma-related osteoarthritis

in Cytokines and Soluble Mediators in Immunity

Leonie Ruths
Jana Hengge
Graciosa Q. Teixeira
Melanie Haffner-Luntzer
Anita Ignatius
Jana Riegger

Frontiers in Immunology

doi 10.3389/fimmu.2024.1470907

3,286 views
1 citation

Hypothesis and Theory

Published on 13 Jan 2025

Healthy individuals genetically at-risk for the development of Pemphigus vulgaris or Alopecia areata share disease-like cytokine dysregulation

in Cytokines and Soluble Mediators in Immunity

Rebekah R. Schwartz
Kristina Seiffert-Sinha
Animesh A. Sinha

Frontiers in Immunology

doi 10.3389/fimmu.2024.1500284

1,311 views

Review

Published on 09 Jan 2025

The role and therapeutic targeting of the CCL2/CCR2 signaling axis in inflammatory and fibrotic diseases

in Cytokines and Soluble Mediators in Immunity

Shan Guo
Qi Zhang
Yingjie Guo
Xiaoyan Yin
Peng Zhang
Tao Mao
Zibin Tian
Xiaoyu Li

Frontiers in Immunology

doi 10.3389/fimmu.2024.1497026

7,405 views
5 citations