Frontiers in Immunology | Molecular Innate Immunity

Original Research

Published on 30 Jan 2023

CFH and CFHR structural variants in atypical Hemolytic Uremic Syndrome: Prevalence, genomic characterization and impact on outcome

in Molecular Innate Immunity

Rossella Piras
Elisabetta Valoti
Marta Alberti
Elena Bresin
Caterina Mele
Matteo Breno
Lucia Liguori
Roberta Donadelli
Miriam Rigoldi
Ariela Benigni

Frontiers in Immunology

doi 10.3389/fimmu.2022.1011580

10,049 views
16 citations

Original Research

Published on 27 Jan 2023

Caspase-11 contributes to site-1 protease cleavage and SREBP1 activation in the inflammatory response of macrophages

in Molecular Innate Immunity

Yinglan Cheng
Ichiro Manabe
Sumio Hayakawa
Yusuke Endo
Yumiko Oishi

Frontiers in Immunology

doi 10.3389/fimmu.2023.1009973

5,275 views
11 citations

Original Research

Published on 26 Jan 2023

Caspase-11 promotes high-fat diet-induced NAFLD by increasing glycolysis, OXPHOS, and pyroptosis in macrophages

in Molecular Innate Immunity

Charles Drummer
Fatma Saaoud
Nirag C. Jhala
Ramon Cueto
Yu Sun
Keman Xu
Ying Shao
Yifan Lu
Huimin Shen
Ling Yang

Frontiers in Immunology

doi 10.3389/fimmu.2023.1113883

24,874 views
55 citations

Mini Review

Published on 26 Jan 2023

Chemical biology tools to interrogate the roles of O-GlcNAc in immunity

in Molecular Innate Immunity

Abhijit Saha
Alberto Fernández-Tejada

Frontiers in Immunology

doi 10.3389/fimmu.2022.1089824

4,728 views
3 citations

Original Research

Published on 26 Jan 2023

Human alveolar macrophage metabolism is compromised during Mycobacterium tuberculosis infection

in Molecular Innate Immunity

Laura E. Mendonca
Erwan Pernet
Nargis Khan
Joaquin Sanz
Eva Kaufmann
Jeffrey Downey
Alexandre Grant
Marianna Orlova
Erwin Schurr
Connie Krawczyk

Frontiers in Immunology

doi 10.3389/fimmu.2022.1044592

10,430 views
30 citations

Review

Published on 26 Jan 2023

The development of COVID-19 treatment

in Molecular Innate Immunity

Yongliang Yuan
Baihai Jiao
Lili Qu
Duomeng Yang
Ruijuan Liu

Frontiers in Immunology

doi 10.3389/fimmu.2023.1125246

46,117 views
204 citations

Original Research

Published on 26 Jan 2023

Inhibition of specific signaling pathways rather than epigenetic silencing of effector genes is the leading mechanism of innate tolerance

in Molecular Innate Immunity

Anna M. Masyutina
Polina V. Maximchik
Georgy Z. Chkadua
Mikhail V. Pashenkov

Frontiers in Immunology

doi 10.3389/fimmu.2023.1006002

2,293 views
5 citations

Brief Research Report

Published on 26 Jan 2023

TLQP-21 is a low potency partial C3aR activator on human primary macrophages

in Molecular Innate Immunity

Xaria X. Li
John D. Lee
Han S. Lee
Richard J. Clark
Trent M. Woodruff

Frontiers in Immunology

doi 10.3389/fimmu.2023.1086673

3,789 views
5 citations

Brief Research Report

Published on 25 Jan 2023

Negative interference with antibody-dependent cellular cytotoxicity mediated by rituximab from its interactions with human serum proteins

in Molecular Innate Immunity

Saeko Yanaka
Rina Yogo
Hirokazu Yagi
Masayoshi Onitsuka
Natsumi Wakaizumi
Yuki Yamaguchi
Susumu Uchiyama
Koichi Kato

Frontiers in Immunology

doi 10.3389/fimmu.2023.1090898

3,465 views
6 citations

Original Research

Published on 25 Jan 2023

Macrophage differentiation is marked by increased abundance of the mRNA 3’ end processing machinery, altered poly(A) site usage, and sensitivity to the level of CstF64

in Molecular Innate Immunity

Srimoyee Mukherjee
Joel H. Graber
Claire L. Moore

Frontiers in Immunology

doi 10.3389/fimmu.2023.1091403

6,002 views
15 citations

Perspective

Published on 25 Jan 2023

Microbial derived antimicrobial peptides as potential therapeutics in atopic dermatitis

in Molecular Innate Immunity

Aaroh Anand Joshi
Marc Vocanson
Jean-Francois Nicolas
Peter Wolf
Vijaykumar Patra

Frontiers in Immunology

doi 10.3389/fimmu.2023.1125635

8,643 views
22 citations

Editorial

Published on 24 Jan 2023

Editorial: Complement: Latest developments regarding structure, mechanism, and connections to other proteolytic pathways

in Molecular Innate Immunity

József Dobó
Péter Gál
Brian V. Geisbrecht

Frontiers in Immunology

doi 10.3389/fimmu.2023.1144038

1,821 views

Original Research

Published on 24 Jan 2023

Phosphoinositol 3-kinase-driven NET formation involves different isoforms and signaling partners depending on the stimulus

in Molecular Innate Immunity

Vanessa de Carvalho Oliveira
Olga Tatsiy
Patrick P. McDonald

Frontiers in Immunology

doi 10.3389/fimmu.2023.1042686

4,906 views
12 citations

Original Research

Published on 24 Jan 2023

Quantitative fluorescence resonance energy transfer-based immunoassay for activated complement C1s

in Molecular Innate Immunity

Jun Ye
Jie Xu
Chuanmeng Zhang
Li Zhu
Sheng Xia

Frontiers in Immunology

doi 10.3389/fimmu.2023.1081793

3,327 views
2 citations

Original Research

Published on 23 Jan 2023

Bi-fluorescent Staphylococcus aureus infection enables single-cell analysis of intracellular killing in vivo

in Molecular Innate Immunity

Kristina D. Hinman
Sonia S. Laforce-Nesbitt
Joshua T. Cohen
Miles Mundy
Joseph M. Bliss
Alexander R. Horswill
Craig T. Lefort

Frontiers in Immunology

doi 10.3389/fimmu.2023.1089111

4,911 views
1 citation

Original Research

Published on 20 Jan 2023

Identification of a forkhead box protein transcriptional network induced in human neutrophils in response to inflammatory stimuli

in Molecular Innate Immunity

Aiten Ismailova
Reyhaneh Salehi-Tabar
Vassil Dimitrov
Babak Memari
Camille Barbier
John H. White

Frontiers in Immunology

doi 10.3389/fimmu.2023.1123344

4,324 views
10 citations