Frontiers in Immunology | Vaccines and Molecular Therapeutics

Original Research

Published on 12 Mar 2025

BCG-derived acellular membrane vesicles elicit antimycobacterial immunity and innate immune memory

in Vaccines and Molecular Therapeutics

Takehiro Yamaguchi
Noriaki Samukawa
Sohkichi Matsumoto
Masayuki Shiota
Masaki Matsumoto
Ryoma Nakao
Satoru Hirayama
Yutaka Yoshida
Akihito Nishiyama
Yuriko Ozeki

Frontiers in Immunology

doi 10.3389/fimmu.2025.1534615

2,180 views

Review

Published on 07 Mar 2025

Current state of cancer immunity cycle: new strategies and challenges of using precision hydrogels to treat breast cancer

in Vaccines and Molecular Therapeutics

Yingze Zhu
Yanlin Su
Yaxin Guo
Xinyue Wang
Zhuoqi Zhang
Yige Lu
Hang Yang
Hui Pang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1535464

1,431 views

Review

Published on 07 Mar 2025

Computational tools and data integration to accelerate vaccine development: challenges, opportunities, and future directions

in Vaccines and Molecular Therapeutics

Lindsey N. Anderson
Charles Tapley Hoyt
Jeremy D. Zucker
Andrew D. McNaughton
Jeremy R. Teuton
Klas Karis
Natasha N. Arokium-Christian
Jackson T. Warley
Zachary R. Stromberg
Benjamin M. Gyori

Frontiers in Immunology

doi 10.3389/fimmu.2025.1502484

2,353 views

Original Research

Published on 07 Mar 2025

Screening and preclinical assessment of novel Mycobacterium tuberculosis recombinant antigens based tuberculin skin testing

in Vaccines and Molecular Therapeutics

Xichao Ou
Eryong Liu
Faiqa Rashid
Shaojun Pei
Guoqin Zhang
Richard Anthony
Ruida Xing
Fei Huang
Hui Xia
Yang Zheng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1498448

1,498 views

Original Research

Published on 06 Mar 2025

Enhanced T-cell immunity and lower humoral responses following 5-dose SARS-CoV-2 vaccination in patients with inborn errors of immunity compared with healthy controls

in Vaccines and Molecular Therapeutics

Vitor Gabriel Lopes da Silva
Gabriela Justamante Händel Schmitz
Kathleen E. Sullivan
Júlia Barbate
Maria Izabel de Haro Azinar
Carolina Sanchez Aranda
Maria Isabel de Moraes-Pinto

Frontiers in Immunology

doi 10.3389/fimmu.2025.1538453

2,047 views

Correction

Published on 06 Mar 2025

Corrigendum: Mannose-modified erythrocyte membrane-encapsulated chitovanic nanoparticles as a DNA vaccine carrier against reticuloendothelial tissue hyperplasia virus

in Vaccines and Molecular Therapeutics

Yangyang Feng
Feng Tang
Sheng Li
Daiyan Wu
Qianqian Liu
Hangyu Li
Xinnan Zhang
Ziwei Liu
Linzi Zhang
Haibo Feng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1566389

732 views

Review

Published on 05 Mar 2025

Opportunities and challenges of mRNA technologies in development of dengue virus vaccine

in Vaccines and Molecular Therapeutics

Xiaoyang Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1520968

2,807 views
1 citation

General Commentary

Published on 04 Mar 2025

Commentary: Inactivated rabies virus vectored MERS-Coronavirus vaccine induces protective immunity in mice, camels, and alpacas

in Vaccines and Molecular Therapeutics

Shengnan Yang
Hanqi Li
Fuxiao Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1549481

1,128 views

Review

Published on 04 Mar 2025

Technological breakthroughs and advancements in the application of mRNA vaccines: a comprehensive exploration and future prospects

in Vaccines and Molecular Therapeutics

Zhimeng Wei
Shuai Zhang
Xingya Wang
Ying Xue
Sheng Dang
Jingbo Zhai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1524317

3,143 views
1 citation

Original Research

Published on 03 Mar 2025

Enhancing AAV-microdystrophin gene therapy after repeat dosing by blocking phagocytosis

in Vaccines and Molecular Therapeutics

Rita Spathis
Deeva Robles Kuriplach
Sabrina Narvesen
Matthew Eybs
Karen Huang
Steven Torres
Madison King
Elizabeth Bagley
Pia Elustondo
Michael W. Lawlor

Frontiers in Immunology

doi 10.3389/fimmu.2025.1527840

2,715 views

Original Research

Published on 28 Feb 2025

Suppression of NLRP3 inflammasome by a small molecule targeting CK1α–β-catenin–NF-κB and CK1α–NRF2–mitochondrial OXPHOS pathways during mycobacterial infection

in Vaccines and Molecular Therapeutics

Qing Guan
Huan Xiong
Xiangyu Song
Sheng Liu
Yuanjun Guang
Qi Nie
Yan Xie
Xiao-Lian Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1553093

2,276 views

Review

Published on 28 Feb 2025

Advancements in the conservation of the conformational epitope of membrane protein immunogens

in Vaccines and Molecular Therapeutics

Aisha Mahboob
Nishat Fatma
Ahmed Faraz
Muntaha Pervez
Mohammad Afeef Khan
Afzal Husain

Frontiers in Immunology

doi 10.3389/fimmu.2025.1538871

1,003 views

Original Research

Published on 27 Feb 2025

Antidrug antibodies to adalimumab do not associate with immunologically related adverse events

in Vaccines and Molecular Therapeutics

Sophie Tourdot
Maria-Dolores Vazquez-Abad
Donna S. Cox
Chun-Hua Cai
Karen Wang
Wuyan Zhang
Christopher Lepsy

Frontiers in Immunology

doi 10.3389/fimmu.2024.1457993

2,130 views

Original Research

Published on 27 Feb 2025

Gut microbiota is associated with persistence of longer-term BNT162b2 vaccine immunogenicity

in Vaccines and Molecular Therapeutics

Ho Yu Ng
Yunshi Liao
Ching Lung Cheung
Ruiqi Zhang
Kwok Hung Chan
Wai-Kay Seto
Wai K. Leung
Ivan F. N. Hung
Tommy T. Y. Lam
Ka Shing Cheung

Frontiers in Immunology

doi 10.3389/fimmu.2025.1534787

1,782 views
1 citation

Original Research

Published on 27 Feb 2025

Gamma-irradiated fowl cholera vaccines formulated with different adjuvants induced antibody response and cytokine expression in chickens

in Vaccines and Molecular Therapeutics

Eyerusalem Belay
Molalegne Bitew
Saddam Mohammed Ibrahim
Bereket Dessalegn
Solomon Lulie Abey
Haileyesus Dejene
Mastewal Birhan
Dawit Duffera
Eyob Asefa
Liyuwork Tesfaw

Frontiers in Immunology

doi 10.3389/fimmu.2025.1513443

2,235 views

Original Research

Published on 27 Feb 2025

Identification of B-cell epitopes of Indian Zika virus strains using immunoinformatics

in Vaccines and Molecular Therapeutics

Rohan Raj Roy
Nitali Tadkalkar
Gururaj Rao Deshpande
Nitin M. Atre
Pratip Shil
Gajanan Sapkal

Frontiers in Immunology

doi 10.3389/fimmu.2025.1534737

3,120 views