MINI REVIEW article
Front. Microbiol.
Sec. Antimicrobials, Resistance and Chemotherapy
Volume 16 - 2025 | doi: 10.3389/fmicb.2025.1558035
This article is part of the Research TopicMitigation of Microbial Biofilm Formation on Medical DevicesView all articles
Ultrasonic Strategies for Mitigating Microbial Adhesion and Biofilm Formation on Medical Surfaces: A Mini Review
Provisionally accepted
Xingang Shao1
Yuanzhe LI2,3*- 1Hebei University of Engineering, Handan, Hebei Province, China
- 2Nanyang Technological University, Singapore, Singapore
- 3The University of Auckland, Auckland, Auckland, New Zealand
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Biofilm formation on medical surfaces poses significant challenges, leading to compromised device functionality and an increased risk of infections. Addressing this issue requires effective strategies that balance efficacy with safety. This mini-review examines the application of ultrasound as a promising approach for biofilm control in medical contexts. Drawing from recent studies, it explores the mechanisms by which ultrasound disrupts biofilms, highlighting its ability to break down extracellular polymeric matrices and enhance the efficacy of antimicrobials. The review also discusses practical considerations, including ultrasound parameter optimization, biocompatibility, and integration with other anti-biofilm strategies. While ultrasound has demonstrated potential in disrupting biofilms, further research is essential to refine these approaches, improve treatment outcomes, and ensure compatibility with medical applications. By advancing our understanding and application of ultrasonic techniques, this field holds promise for improving patient safety and enhancing medical device longevity.
Keywords: Biofilm adhesion, Ultrasonic techniques, Medical Surfaces, biofilm disruption, clinical applications
Received: 09 Jan 2025; Accepted: 03 Jun 2025.
Copyright: © 2025 Shao and LI. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Yuanzhe LI, Nanyang Technological University, Singapore, Singapore
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.