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ORIGINAL RESEARCH article

Front. Microbiol.

Sec. Antimicrobials, Resistance and Chemotherapy

Volume 16 - 2025 | doi: 10.3389/fmicb.2025.1569242

This article is part of the Research TopicEmerging Antimicrobials: Sources, Mechanisms of Action, Spectrum of Activity, Combination Antimicrobial Therapy, and Resistance MechanismsView all 30 articles

Methicillin and Inducible Clindamycin Resistance in Clinical Staphylococcus aureus Isolates: A Cross-Sectional Study from Northwest Ethiopia

Provisionally accepted
  • 1College of Health Science, Debark University, Debark, Ethiopia
  • 2Debre Markos University, Debre Marqos, Ethiopia
  • 3Debre Markos Comprehensive Specialized Hospital, Debre Markos, Amhara, Ethiopia

The final, formatted version of the article will be published soon.

Background: Staphylococcus aureus is a major pathogenic bacterium associated with high morbidity and mortality worldwide. It exhibits resistance to multiple antibiotics, complicating treatment options.Despite its clinical significance, there is limited data on the prevalence of S. aureus infections and the patterns of methicillin and inducible clindamycin resistance, particularly in Ethiopia. Understanding these resistance trends is essential for guiding appropriate therapy and improving patient outcomes.

Keywords: antimicrobial resistance, Prevalence, S. aureus, Methicillin Resistance, Inducible clindamycin resistance, Ethiopia 1. Introduction

Received: 31 Jan 2025; Accepted: 22 May 2025.

Copyright: © 2025 Addis, Aschale, Fenta, Teffera, Melkamu, Tigab and Dilnessa. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Tebelay Dilnessa, Debre Markos University, Debre Marqos, Ethiopia

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