ORIGINAL RESEARCH article
Front. Microbiol.
Sec. Infectious Agents and Disease
Volume 16 - 2025 | doi: 10.3389/fmicb.2025.1582163
This article is part of the Research TopicTuberculosis Transmission: A Battle Between the Host and the PathogenView all articles
Epidemiological Changes in Tuberculosis and Genotyping Characteristics of Mycobacterium Tuberculosis in Ningxia, China
Provisionally accepted
- 1Fourth People's Hospital of Ningxia, Yinchuan, China
- 2The College of Public Health, Ningxia Medical University, China, Yinchuan, China
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China is one of the three countries with the largest TB burden globally, with an increased number of patients reported in 2021. In this study, we aimed to investigate the epidemiological profile of tuberculosis (TB) and the genotype characteristics of Mycobacterium tuberculosis (MTB) in the Ningxia Hui Autonomous Region, China, from 2005 to 2023, to provide a scientific basis for the precise prevention and control of TB. Epidemiological data on TB in Ningxia were obtained from the China Disease Control and Prevention Information System from 2005 to 2023. The temporal trend of TB incidence was assessed using a Joinpoint regression analysis (Joinpoint 5.2.0), and spatial autocorrelation analyses were performed using ArcGIS 10.8. Spoligotyping and McSpoligotyping based on 222 isolated MTB strains. From 2005 to 2023, 51,345 patients with TB were reported in Ningxia. The incidence of TB decreased from 48.22/100,000 in 2005 to 30.47/100,000 in 2023.Joinpoint analysis showed that the incidence of TB in all age groups exhibited an overall decreasing trend. The incidences were significantly lower among urban residents than among rural residents. A spatial analysis showed that the southern mountainous area had a high incidence, with an average annual incidence of more than 60/100,000 in the Xiji, Lund, and Haiyuan counties, and this showed
Keywords: tuberculosis (TB), Beijing genotype, Spatial clustering, Epidemiological trend, prevention and control
Received: 24 Feb 2025; Accepted: 13 May 2025.
Copyright: © 2025 Liu, 吕, Chen, Ma, Liu and Jiang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Yinglong Ma, Fourth People's Hospital of Ningxia, Yinchuan, China
Bofei Liu, Fourth People's Hospital of Ningxia, Yinchuan, China
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