ORIGINAL RESEARCH article
Front. Microbiol.
Sec. Infectious Agents and Disease
Volume 16 - 2025 | doi: 10.3389/fmicb.2025.1675452
Erwinia wuhanensis sp. nov. isolated from human blood
Provisionally accepted
- 1Department of Medical Laboratory, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
- 2Hubei Provincial Engineering Research Center of Intestinal Microecological Diagnostics, Therapeutics, and Clinical Translation, Wuhan, China
- 3Chinese Center for Disease Control and Prevention, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Beijing, China
- 4Cancer Research Institute of Wuhan, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
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A novel Erwinia strain, BC051422T, was isolated from the blood of a patient at the Central Hospital of Wuhan, Wuhan, PR China, in 2022. The strain was identified as gram-negative, facultatively anaerobic, motile, and rod-shaped. Preliminary analysis based on the 16S rRNA gene sequence and multilocus sequence analysis of the atpD, infB, rpoB, and gyrB genes unveiled that this strain is closely related to Erwinia members. Whole-genome sequencing was performed, and the average nucleotide identity (ANI) and in silico DNA–DNA hybridization (isDDH) values between strain BC051422T and type strains of all known Erwiniaceae species ranged from 68.8% to 83.4% and 19.2% to 35.5%, respectively, which below the accepted species delineation thresholds of 95% for ANI and 70% for isDDH. The major cellular fatty acids of strain BC051422T were C16:0, C16:1 ω7c/C16:1 ω6c, and C17: 0 cyclo, consistent with profiles similar to those observed in other Erwinia species. The genomic DNA G+C content was 55.95 mol%. Strain BC051422T can be differentiated from other Erwinia species by its ability to ferment sucrose, but its inability to metabolize mannose, rhamnose, melibiose, and sorbitol. Genotypic and phenotypic characteristics together support the classification of strain BC051422T as a novel species of the genus Erwinia, for which the name Erwinia wuhanensis sp. nov. is proposed. The type strain of E. wuhanensis sp. nov. is BC051422T (=GDMCC 1.4074T = JCM 36319T).
Keywords: Erwinia wuhanensis, Novel species, Bacteria, Genome, 16S rRNA
Received: 29 Jul 2025; Accepted: 20 Aug 2025.
Copyright: © 2025 Zhang, Zhan, Yang and Lu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Yingmiao Zhang, Department of Medical Laboratory, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
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