Weiwei Ma
Lian Lian
Lidong Guo
Lili Huangby Ma, W., Lian, L., Guo, L., Wu, Y., and Huang, L. (2025). Front. Microbiol. 16:1577799. doi: 10.3389/fmicb.2025.1577799
In the published article, there was an error in the article title.
The title of this article was erroneously given as:
“Lactobacillus rhamnosus Glory LG12 preventives loperamide-induced constipation in mice by modulating intestinal flora and metabolic pathways”,
The correct title should be:
“Lacticaseibacillus rhamnosus Glory LG12 preventives loperamide-induced constipation in mice by modulating intestinal flora and metabolic pathways”.
There was a mistake in the caption of Figure 1, page 5 as published. The position of “a–e: Different letters indicate (p < 0.05), and the same letters or no letters indicate no significant difference (n = 10)” is incorrect.
The corrected caption of Figure 1 appears below:
“Effect of L. rhamnosus Glory LG12 on defecation index in mice. (a) Time to the first black stool defecation; (b) Number of grains in 5 h defecation; (c) Water content of defecation; (d) Small intestine transit rate. a–e: Different letters indicate (p < 0.05), and the same letters or no letters indicate no significant difference (n = 10).”
There was a mistake in the caption of Figure 2, page 7 as published. The legend for Figure 2 is incomplete, as it does not include the statement “a–d: Different letters indicate (p < 0.05), and the same letters or no letters indicate no significant difference (n = 3).
The corrected caption of Figure 2 appears below:
“Effect of L. rhamnosus Glory LG12 on pathological changes in mice colon tissues (original magnification × 200) and colonic pathology score. (a) Pathological changes in colon tissues, (b) Colonic pathology score. a–d: Different letters indicate (p < 0.05), and the same letters or no letters indicate no significant difference (n = 3).”
“Lactobacillus rhamnosus Glory LG12” used in the article needs to be updated to the latest strain name “Lacticaseibacillus rhamnosus Glory LG12”.
A correction has been made to the Citation, page 1.
The Citation previously stated:
“Ma W, Lian L, Guo L, Wu Y and Huang L (2025) Lactobacillus rhamnosus Glory LG12 preventives loperamide-induced constipation in mice by modulating intestinal flora and metabolic pathways. Front. Microbiol. 16:1577799. doi: 10.3389/fmicb.2025.1577799
The corrected Citation appears below:
“Ma, W., Lian, L., Guo, L., Wu, Y., and Huang, L. (2025) Lacticaseibacillus rhamnosus Glory LG12 preventives loperamide-induced constipation in mice by modulating intestinal flora and metabolic pathways. Front. Microbiol. 16:1577799. doi: 10.3389/fmicb.2025.1577799”
A correction has been made to 1 Introduction, page 2.
This sentence previously stated:
“Lactobacillus rhamnosus has been shown to regulate intestinal flora disorders and maintain intestinal microecology in mice (Mei et al., 2024). Han et al. (2024) administered Lactobacillus rhamnosus JYLR-127 (L. rhamnosus JYLR-127) to patients with constipation after bone fracture, and the results showed that the administration of Lactobacillus rhamnosus was beneficial to the reconstruction of the destroyed intestinal flora and the modification of intestinal microecology. He et al. (2022) detected a significant increase in the abundance of Lactobacillus rhamnosus in the intestinal tract of mice after stopping gavage of Lactobacillus rhamnosus LR22 (L. rhamnosus LR22) for 2 weeks, suggesting that Lactobacillus rhamnosus colonised the intestinal tract of mice. The results showed that high-dose Lactobacillus rhamnosus had better colonization effects than low-dose Lactobacillus rhamnosus, thereby better regulating intestinal microbiota and relieving constipation.”
The corrected sentence appears below:
“Lacticaseibacillus rhamnosus has been shown to regulate intestinal flora disorders and maintain intestinal microecology in mice (Mei et al., 2024). Han et al. (2024) administered Lactobacillus rhamnosus JYLR-127 (L. rhamnosus JYLR-127) to patients with constipation after bone fracture, and the results showed that the administration of Lacticaseibacillus rhamnosus was beneficial to the reconstruction of the destroyed intestinal flora and the modification of intestinal microecology. He et al. (2022) detected a significant increase in the abundance of Lacticaseibacillus rhamnosus in the intestinal tract of mice after stopping gavage of Lactobacillus rhamnosus LR22 (L. rhamnosus LR22) for 2 weeks, suggesting that Lacticaseibacillus rhamnosus colonised the intestinal tract of mice. The results showed that high-dose Lacticaseibacillus rhamnosus had better colonization effects than low-dose Lacticaseibacillus rhamnosus, thereby better regulating intestinal microbiota and relieving constipation.”
A correction has been made to 1 Introduction, page 3.
This sentence previously stated:
“Available studies have shown that Lactobacillus rhamnosus Glory LG12 (L. rhamnosus Glory LG12) can significantly increase the concentrations of lactic acid, acetic acid and butyric acid in the intestinal tract of mice (Ma et al., 2024).”
The corrected sentence appears below:
“Available studies have shown that Lacticaseibacillus rhamnosus Glory LG12 (L. rhamnosus Glory LG12) can significantly increase the concentrations of lactic acid, acetic acid and butyric acid in the intestinal tract of mice (Ma et al., 2024).”
A correction has been made to 2 Materials and methods, 2.2 Lactobacillus rhamnosus Glory LG12 suspension preparation, page 2.
This heading previously stated:
“2.2 Lactobacillus rhamnosus Glory LG12 suspension preparation”
The corrected heading appears below:
“2.2 Lacticaseibacillus rhamnosus Glory LG12 suspension preparation”
A correction has been made to 3 Results, 3.1 Effect of Lactobacillus rhamnosus Glory
LG12 on body weight in mice, page 5.
This heading previously stated:
“3.1 Effect of Lactobacillus rhamnosus Glory LG12 on body weight in mice”
The corrected sentence appears below:
“3.1 Effect of Lacticaseibacillus rhamnosus Glory LG12 on body weight in mice”
A correction has been made to 3 Results, 3.2 Effect of Lactobacillus rhamnosus Glory
LG12 on defecation indices in mice, page 5.
This heading previously stated:
“3.2 Effect of Lactobacillus rhamnosus Glory LG12 on defecation indices in mice”
The corrected heading appears below:
“3.2 Effect of Lacticaseibacillus rhamnosus Glory LG12 on defecation indices in mice”
A correction has been made to 3 Results, 3.3 Effect of Lactobacillus rhamnosus Glory
LG12 on pathological changes in mice colon tissue, page 5.
This heading previously stated:
“3.3 Effect of Lactobacillus rhamnosus Glory LG12 on pathological changes in mice
colon tissue”
The corrected heading appears below:
“3.3 Effect of Lacticaseibacillus rhamnosus Glory LG12 on pathological changes in mice colon tissue”
A correction has been made to 3 Results, 3.4 Effect of Lactobacillus rhamnosus Glory LG12 on serum neurotransmitters in mice, page 6.
This heading previously stated:
“3.4 Effect of Lactobacillus rhamnosus Glory LG12 on serum neurotransmitters in mice”
The corrected heading appears below:
“3.4 Effect of Lacticaseibacillus rhamnosus Glory LG12 on serum neurotransmitters in mice”
A correction has been made to 3 Results, 3.5 Effect of Lactobacillus rhamnosus Glory
LG12 on inflammatory factors in mice, page 7.
This heading previously stated:
“3.5 Effect of Lactobacillus rhamnosus Glory LG12 on inflammatory factors in mice”
The corrected sentence appears below:
“3.5 Effect of Lacticaseibacillus rhamnosus Glory LG12 on inflammatory factors in mice”
A correction has been made to 3 Results, 3.6 Effect of Lactobacillus rhamnosus Glory
LG12 on intestinal flora in mice, page 8.
This heading previously stated:
“3.6 Effect of Lactobacillus rhamnosus Glory LG12 on intestinal flora in mice”
The corrected heading appears below:
“3.6 Effect of Lacticaseibacillus rhamnosus Glory LG12 on intestinal flora in mice”
A correction has been made to 3 Results, 3.7 Effect of Lactobacillus rhamnosus Glory
LG12 on SCFAS in mice, page 9.
This heading previously stated:
“3.7 Effect of Lactobacillus rhamnosus Glory LG12 on SCFAS in mice”
The corrected heading appears below:
“3.7 Effect of Lacticaseibacillus rhamnosus Glory LG12 on SCFAS in mice”
A correction has been made to 4 Discussion, page 12.
This sentence previously stated:
“The effect of Lactobacillus rhamnosus on constipation can be evaluated by observing and measuring the defecation indexes (water content of defecation, time to first black stool defecation, small intestine transit rate, and number of grains in 5 h defecation) in mice.”
The corrected sentence appears below:
“The effect of Lacticaseibacillus rhamnosus on constipation can be evaluated by observing and measuring the defecation indexes (water content of defecation, time to first black stool defecation, small intestine transit rate, and number of grains in 5 h defecation) in mice.”
A correction has been made to 4 Discussion, page 12.
This sentence previously stated:
“By HE staining, the structure and morphology of colonic tissues can be visualised, which is helpful to directly determine whether Lactobacillus rhamnosus has a reparative effect on pathological intestinal damage.”
The corrected sentence appears below:
“By HE staining, the structure and morphology of colonic tissues can be visualised, which is helpful to directly determine whether Lacticaseibacillus rhamnosus has a reparative effect on pathological intestinal damage.”
A correction has been made to 4 Discussion, page 12.
This sentence previously stated:
“Li et al. (2024) gavage of Lactobacillus paracasei NCU-04 (L. paracasei NCU-04) to constipated mice showed that L. paracasei NCU-04 attenuated pathological changes in the colon of constipated mice.”
The corrected sentence appears below:
“Li et al. (2024) gavage of Lacticaseibacillus paracasei NCU-04 (L. paracasei NCU-04) to constipated mice showed that L. paracasei NCU-04 attenuated pathological changes in the colon of constipated mice.”
A correction has been made to 4 Discussion, page 14.
This sentence previously stated:
“Zheng et al. (2020) showed that SCFAS were closely associated with Lactobacillus rhamnosus repair of intestinal tight junctions and reduction of pro-inflammatory factor levels.”
The corrected sentence appears below:
“Zheng et al. (2020) showed that SCFAS were closely associated with Lacticaseibacillus rhamnosus repair of intestinal tight junctions and reduction of pro-inflammatory factor levels.”
A correction has been made to 5 Conclusion, page 15.
This sentence previously stated:
“Meanwhile, with the increase of the dose of Lactobacillus rhamnosus, the relief effect on constipation was more significant.”
The corrected sentence appears below:
“Meanwhile, with the increase of the dose of Lacticaseibacillus rhamnosus, the relief effect on constipation was more significant.”
The original article has been updated.
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Keywords: Lacticaseibacillus rhamnosus Glory LG12, constipation, intestinal flora, short-chain fatty acids, metabolic pathway
Citation: Ma W, Lian L, Guo L, Wu Y and Huang L (2025) Correction: Lacticaseibacillus rhamnosus Glory LG12 preventives loperamide-induced constipation in mice by modulating intestinal flora and metabolic pathways. Front. Microbiol. 16:1676952. doi: 10.3389/fmicb.2025.1676952
Received: 31 July 2025; Accepted: 01 August 2025;
Published: 14 August 2025.
Approved by:
Frontiers Editorial Office, Frontiers Media SA, SwitzerlandCopyright © 2025 Ma, Lian, Guo, Wu and Huang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Lili Huang, aHVhbmdsaWxpQGhsanVjbS5uZXQ=