REVIEW article
Front. Microbiol.
Sec. Antimicrobials, Resistance and Chemotherapy
Volume 16 - 2025 | doi: 10.3389/fmicb.2025.1694108
This article is part of the Research TopicAdvancements in Diversity and Drug Resistance Mechanisms in Mycobacterial DiseasesView all 15 articles
The Rising Challenge of Candida auris: Insights into Its Transmission, Drug Resistance, and Infection Control Strategies
Provisionally accepted
- 1Nanjing Drum Tower Hospital, Nanjing, China
- 2Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing, China
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Candida auris (also known as Candidozyma auris) is a newly emerged pathogenic fungus that has garnered widespread attention globally, particularly in healthcare settings. Its rapid transmission, association high pathogenicity, and resistance to multiple antifungal agents have made it a significant public health challenge. C. auris commonly causes invasive infections in immunocompromised patients, and its resistance to various antifungal drugs complicates treatment strategies. This review summarizes the epidemiological characteristics, transmission routes, risk factors, and resistance mechanisms of C. auris, with a focus on its hospital transmission dynamics and environmental persistence. Additionally, we discuss current control and prevention strategies, including early detection, infection control measures, and the rational use of antifungal agents. Finally, the article looks ahead to future research directions, particularly the potential for vaccine development and immunotherapy, aiming to provide scientific insights for optimizing clinical diagnosis and treatment strategies.
Keywords: Candida auris, Epidemiology, transmission routes, Resistance, outbreak, Infection prevention and control, Prevention strategies
Received: 28 Aug 2025; Accepted: 17 Oct 2025.
Copyright: © 2025 Zhang, Cao, Liu and Gao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Shuo Gao, shuoshuo65@163.com
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