MINI REVIEW article
Front. Microbiol.
Sec. Virology
Integrated PRRSV prevention and control strategy based on the One Health concept: across the boundaries of virology, ecology and public health
Provisionally accepted
- College of Life Sciences, Longyan University, Longyan, China
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) poses a major threat to global swine production, with substantial economic losses and serious animal welfare concerns. Although PRRSV is not considered a zoonotic agent, its control exemplifies the necessity of a One Health approach, incorporating virological, ecological, immunological, and agricultural dimensions. This article contends that the impact of PRRSV extends beyond porcine populations, significantly contributing to the emergence of antimicrobial resistance (AMR) via secondary bacterial infections and the consequent misuse of antibiotics. Moreover, the environmental persistence of the virus and its potential for indirect transmission raise critical ecological questions that remain unresolved. By synthesizing current evidence, this review delineates the complex interrelationships among PRRSV outbreaks, patterns of antimicrobial use, and environmental contamination. This study propose an integrated One Health framework for PRRSV surveillance and control, emphasizing the implementation of genomic tools, systematic environmental monitoring, and enhanced collaboration among public health, veterinary, and environmental sectors. Integrating these disciplines is crucial to alleviating the multidimensional challenges posed by PRRSV, thereby protecting animal welfare, supporting sustainable agriculture, and strengthening global public health.
Keywords: One Health, Porcine Reproductive and Respiratory Syndrome Virus, antimicrobial resistance, Integrated control strategy, Environmental Monitoring
Received: 05 Oct 2025; Accepted: 12 Nov 2025.
Copyright: © 2025 Chen, Weng, Huang, Li and Duan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Xiaobing Li, 82022010@lyun.edu.cn
Dianning Duan, 82014027@lyun.edu.cn
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.