Frontiers in Molecular Biosciences

Original Research

Accepted on 15 Jan 2026

Sex-based antibody subclass maturation drives direct enzymatic inhibition in Fabry disease patients receiving enzyme replacement therapy

in Molecular Diagnostics and Therapeutics

Tomas Baldwin
Hibba Kurdi
Ivan Doykov
Stefania Rosmini
Sabrina Nordin
Joao Bicho Augusto
Rebecca Kozor
Julien Colomban Baruteau
James Davison
David Moreno-Martinez

Frontiers in Molecular Biosciences

203 views

Review

Published on 15 Jan 2026

Target temperature management in acute ischemic stroke

in Molecular Diagnostics and Therapeutics

Lan Gao
Ting Yang
Hong Chong
Longfei Wu
Jinming Han

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1728769

905 views

Review

Published on 15 Jan 2026

Regulatory QTLs affecting miRNA-mRNA interactions in cancer: mechanisms, methods, and clinical implications

in Cellular Biochemistry

Vivek Kumar
Rohit Shukla
Amit Chaudhary
Mansi Gautam

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1749396

1,116 views

Original Research

Published on 15 Jan 2026

A novel tumor-progressing fibroblast signature derived from single-cell RNA sequencing enables prognostic stratification and reveals RNF11 as a functional regulator in bladder cancer

in Molecular Diagnostics and Therapeutics

Miaoyu Zhang
Liangbin Lin
He Xu
Xu Su
Kui Zeng
Fangyang Zhong
Xianchao Su
Jie Chen
Min Cao
Hui Yu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1722809

858 views

Brief Research Report

Published on 15 Jan 2026

CSDE1 stabilizes AGO2 in embryonic stem cells

in RNA Networks and Biology

Yuguan Jiang
Mason Waye
Pavan Kumar Kakumani

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1745258

902 views

Original Research

Published on 15 Jan 2026

Exploring the risk stratification of carotid plaque hemodynamic using four-dimensional blood flow technology

in Molecular Diagnostics and Therapeutics

Si-yuan Zhang
Hong-liang Zhao
Xiao-wei Song
Jian Wu
Rui Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1685377

764 views

Review

Accepted on 14 Jan 2026

Catalpol: An natural multifunctional iridoid glycoside with promising therapeutic properties

in Cellular Biochemistry

Guannan He
Jing Song
Ruixuan Ma
Yixing Zhou
Yamin Xue
Fa-Rong Zhang

Frontiers in Molecular Biosciences

240 views

Review

Published on 14 Jan 2026

Origin of the clock in Neurospora crassa

in Nanobiotechnology

Ahmad Al-Omari
Cara Altimus
Jonathan Arnold
Sam Arsenault
Suchendra Bhandarkar
Shishir Bhusal
Christian Caranica
Jia Hwei Cheong
Zhaojie Deng
Arthur S. Edison

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1697003

1,446 views

Review

Accepted on 13 Jan 2026

Roles of Mitochondrial Complexes in Non-Alcoholic Fatty Liver Disease

in Mitochondria in Physiology and Disease

kai wang
li wang
jiamin ning
Dexin Li

Frontiers in Molecular Biosciences

296 views

Methods

Accepted on 13 Jan 2026

Quantifying cytoskeletal protein interactions with Far Western Blotting

in Protein Biochemistry for Basic and Applied Sciences

Marcelo Melo
Elizabeth Phillippi
Mark Schultz
Susan Shen
Hatem El-Shanti

Frontiers in Molecular Biosciences

173 views

Original Research

Published on 13 Jan 2026

Reformulation of the protein databank for real-time search of geometrical attributes of protein structures

in Structural Biology

Musa Azeem
Christopher Lee
Aaron Hein
Christopher Ott
Homayoun Valafar

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1694750

883 views

Hypothesis and Theory

Accepted on 12 Jan 2026

Network-Driven Computational Framework Identifies FDA-Approved Drug Repurposing Across Heterogeneous Brain Cancers

in Biological Modeling and Simulation

Om Prakash

Frontiers in Molecular Biosciences

256 views

Review

Published on 12 Jan 2026

Liquid biopsy in cancer diagnosis and prognosis: a paradigm shift in precision oncology

in Molecular Diagnostics and Therapeutics

Rayane da Silva Abreu
Danielle Dias Pinto Ferreira
Natassia Silva de Araujo
Samuel Horita
Tatiana Martins Tilli
Wim Degrave
Aline dos Santos Moreira
Mariana Caldas Waghabi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1708518

1,834 views

Original Research

Published on 12 Jan 2026

Identification of DNASE1L3 as a novel biomarker of clinical stage in liver hepatocellular carcinoma

in Molecular Diagnostics and Therapeutics

Weina Xue
Shuying Xie
Tong Wu
Ruixi Li
Dingyan Lu
Shuaishuai Chen
Yue Xu
Yonglin Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1681888

832 views

Original Research

Published on 12 Jan 2026

Construction and validation of a predictive model for hypothermia complication during endoscopic thyroidectomy for thyroid cancer

in Molecular Diagnostics and Therapeutics

Hui Ye
Lu Xia
Tian Zhan
Haiwei Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1758239

656 views

Original Research

Published on 12 Jan 2026

JAK-centric explainable few-shot gene-expression diagnosis framework for alopecia via MultiPLIER priors and relation-style set-to-set comparison

in Molecular Diagnostics and Therapeutics

Nanlan Yu
Ling Ran
Xinrong Gong
Junfei Teng
Shulei Liu
Zhiqiang Song

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1753206

998 views

Review

Published on 12 Jan 2026

Circular RNAs: roles in hepatocellular carcinoma immune regulation, implications in immunotherapy, and prospects for clinical translation

in RNA Networks and Biology

Yifan Chen
Jiayi Zhao
Rui Pu
Chao Fu
Zishuai Li
Jianhua Yin
Guangwen Cao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1750832

1,028 views

Review

Published on 12 Jan 2026

DNA methylation and prediction of biological age

in Genome Organization and Dynamics

Yanfang Chen
Xiangshu Cheng
Shaoping Ji

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1734464

1,030 views

Original Research

Published on 12 Jan 2026

Bromo- and chloro-substituted flavones induce apoptosis and modulate cell death pathways in canine lymphoma and leukemia cells - a comparative in vitro study

in Molecular Recognition

Anita Dudek
Ewa Dejnaka
Joanna Sulecka-Zadka
Martyna Perz
Agnieszka Krawczyk-Łebek
Edyta Kostrzewa-Susłow
Hanna Pruchnik
Aleksandra Pawlak

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1738255

913 views

Original Research

Accepted on 09 Jan 2026

Expanding the genetic code: phage-driven evolution of pyrrolysyl-synthetase for site-specific incorporation of synthetic phenylalanine and tyrosine derivatives

in Protein Biochemistry for Basic and Applied Sciences

Dakhnevich Anastasia
Sabina Miasoutova
Danila Iliushin
Aleksey Rozanov
Roman Ivanov

Frontiers in Molecular Biosciences

263 views

Mini Review

Published on 09 Jan 2026

Redox metabolism in cell senescence: focusing on contributions from the metabolomic field

in Metabolomics

Eliana Chacón
Guillermo Grünwaldt
Inés Marmisolle
Jennyfer Martínez
Celia Quijano

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1754469

1,119 views

Original Research

Published on 09 Jan 2026

Isolation, characterization, and biological evaluation of endophytic fungi from Phragmites australis: experimental and computational insights

in Protein Biochemistry for Basic and Applied Sciences

Dina Mahfouz Eskander
Mohamed E. El Awady
Mohamed Ali
Asmaa M. Fahim
Ahmed A. Hamed
Basel Sitohy

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1713876

1,010 views

Editorial

Published on 09 Jan 2026

Editorial: Tumor-host interactions: metabolic and signaling pathways altered in cancer, immune and stromal cells

in Cellular Biochemistry

Joanna Kopecka
Valentina Audrito

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1778371

638 views

Brief Research Report

Published on 08 Jan 2026

Differential roles for CLA-1L and UNC-10 in endosomal maturation and peptide release at C. elegans synapses impacting lifespan

in Cellular Biochemistry

Mia Krout
Elena Miciulis
Phong Q. Lai
Janet E. Richmond

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1675073

1,007 views

5,856 articles

articles

Sex-based antibody subclass maturation drives direct enzymatic inhibition in Fabry disease patients receiving enzyme replacement therapy

Target temperature management in acute ischemic stroke

Regulatory QTLs affecting miRNA-mRNA interactions in cancer: mechanisms, methods, and clinical implications

A novel tumor-progressing fibroblast signature derived from single-cell RNA sequencing enables prognostic stratification and reveals RNF11 as a functional regulator in bladder cancer

CSDE1 stabilizes AGO2 in embryonic stem cells

Exploring the risk stratification of carotid plaque hemodynamic using four-dimensional blood flow technology

Catalpol: An natural multifunctional iridoid glycoside with promising therapeutic properties

Origin of the clock in Neurospora crassa

Roles of Mitochondrial Complexes in Non-Alcoholic Fatty Liver Disease

Quantifying cytoskeletal protein interactions with Far Western Blotting

Reformulation of the protein databank for real-time search of geometrical attributes of protein structures

Network-Driven Computational Framework Identifies FDA-Approved Drug Repurposing Across Heterogeneous Brain Cancers

Liquid biopsy in cancer diagnosis and prognosis: a paradigm shift in precision oncology

Identification of DNASE1L3 as a novel biomarker of clinical stage in liver hepatocellular carcinoma

Construction and validation of a predictive model for hypothermia complication during endoscopic thyroidectomy for thyroid cancer

JAK-centric explainable few-shot gene-expression diagnosis framework for alopecia via MultiPLIER priors and relation-style set-to-set comparison

Circular RNAs: roles in hepatocellular carcinoma immune regulation, implications in immunotherapy, and prospects for clinical translation

DNA methylation and prediction of biological age

Bromo- and chloro-substituted flavones induce apoptosis and modulate cell death pathways in canine lymphoma and leukemia cells - a comparative in vitro study

Expanding the genetic code: phage-driven evolution of pyrrolysyl-synthetase for site-specific incorporation of synthetic phenylalanine and tyrosine derivatives

Redox metabolism in cell senescence: focusing on contributions from the metabolomic field

Isolation, characterization, and biological evaluation of endophytic fungi from Phragmites australis: experimental and computational insights

Editorial: Tumor-host interactions: metabolic and signaling pathways altered in cancer, immune and stromal cells

Differential roles for CLA-1L and UNC-10 in endosomal maturation and peptide release at C. elegans synapses impacting lifespan