Frontiers in Molecular Biosciences

Editorial

Published on 09 Jan 2026

Editorial: Tumor-host interactions: metabolic and signaling pathways altered in cancer, immune and stromal cells

in Cellular Biochemistry

Joanna Kopecka
Valentina Audrito

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2026.1778371

655 views

Brief Research Report

Published on 08 Jan 2026

Differential roles for CLA-1L and UNC-10 in endosomal maturation and peptide release at C. elegans synapses impacting lifespan

in Cellular Biochemistry

Mia Krout
Elena Miciulis
Phong Q. Lai
Janet E. Richmond

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1675073

1,036 views

Original Research

Published on 08 Jan 2026

Glycine attenuates sepsis-induced white matter injury by modulating gut microbiota

in Molecular Diagnostics and Therapeutics

Jingfei Liu
Li Zhang
Chunyang Feng
Ye Li
Huiling Wu
Xueer Wang
Dong Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1733207

1,306 views

Original Research

Published on 08 Jan 2026

A novel prognostic model based on epithelial cell progression genes identifies OAS1 as a suppressor of bladder cancer aggressiveness

in Molecular Diagnostics and Therapeutics

Xu Su
Hui Yu
Miaoyu Zhang
Kui Zeng
Fangyang Zhong
Xuerui Chen
Yuanbiao Guo
Liangbin Lin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1716130

998 views

Review

Published on 07 Jan 2026

Research progress on oral glucagon-like peptide-1 receptor agonists in the treatment of diabetes mellitus type 2

in Molecular Diagnostics and Therapeutics

Qian Shao
Juan Xiong
Jing Wu
Jingxin Mao
Qing Hu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1729904

1,354 views

Original Research

Published on 07 Jan 2026

Hypoxia-induced immunosuppression in uveal melanoma is mediated by CD63+ exosomes delivering lactate to reprogram immune cells

in Molecular Diagnostics and Therapeutics

Lei Dong
Suilian Zheng
Yixia Feng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1743009

1,024 views

Original Research

Published on 07 Jan 2026

Cellular insights into transposable elements in Alzheimer’s disease

in Genome Organization and Dynamics

Vikas Kumar
Samuel Beck

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1642599

1,346 views

Original Research

Published on 07 Jan 2026

Forsythiaside a facilitates autophagy to ameliorate chronic nonbacterial prostatitis in rats by blocking the PKCα/NF-κB pathway

in Cellular Biochemistry

Xingwei Yu
Hongao Tan
Yunqiu Gao
Dandan Qiu
Yan Zhu
Haixin Qi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1665650

578 views

Original Research

Published on 07 Jan 2026

A diverse satellite DNA repertoire in Limnoperna fortunei: insights into genome structure and chromosomal organization

in Genome Organization and Dynamics

Jonathan Pena Castro
Tiago Marafiga Degrandi
Allan Oliveira Leal
Augusto Luiz Ferreira Júnior
Mara Cristina de Almeida
Roberto Ferreira Artoni

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1733652

945 views

Mini Review

Published on 07 Jan 2026

Pharmacophore modeling: advances and pitfalls

in Biological Modeling and Simulation

Mahmoud Y. Elsaka
M. Modather Taha
Amr Tayel
Haytham O. Tawfik
Mahmoud A. A. Ibrahim
Tamer Shoeib

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1760982

1,097 views

Original Research

Published on 07 Jan 2026

Effect of treatment duration on the associations between three modern antidiabetic drugs and survival outcomes of lung cancer in China

in Metabolomics

Zijia Chen
Xiaonan Wang
Zhongtao Zhang
Lu Yang
Chao Lei
Yupeng Di
Ye Huang
Yan Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1701515

850 views

Original Research

Published on 07 Jan 2026

Herbal monomer–based therapeutic insights from traditional Chinese medicine in myocardial infarction

in Molecular Diagnostics and Therapeutics

Nan Bian
Libo Xia
Xianqiu Xiong
Yingyu Chen
Ying Chen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1721931

1,005 views

Review

Accepted on 06 Jan 2026

Nucleolus as a cornerstone linking proliferation and metabolism to cellular responses to stress: involvement of transcription factors MYC and p53

in Cellular Biochemistry

Anastasiia Moraleva
Nadezhda Antipova
Pankrat Pavlov
Kira Dobrochaeva
Yury Rubtsov

Frontiers in Molecular Biosciences

268 views

Original Research

Published on 06 Jan 2026

Advancing Trypanosoma cruzi N-myristoyltransferase as a drug target for Chagas disease through in silico discovery and biochemical evaluation

in Molecular Diagnostics and Therapeutics

Diana González García
Angel Torres
Alan Talevi
Lucas N. Alberca
Miguel A. Beltran
Frida Lara
Marina Da Silva Ferreira
Priscila S. G. Farani
Igor C. Almeida
Rosa A. Maldonado

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1666768

1,224 views

Review

Published on 06 Jan 2026

Strategies of AAV capsid engineering for targeted delivery to brain, muscle, and retina

in Molecular Diagnostics and Therapeutics

Xinyuan Xu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1750807

1,856 views

Original Research

Published on 06 Jan 2026

Pyrrolopyrimidine derivatives as dual COX-2/ACE2 inhibitors: design, synthesis, and anti-inflammatory evaluation

in Cellular Biochemistry

Hala Afifi
Samar S. Fatahala
Rania H. Abd El-Hameed
Shahenda Mahgoub
Radwan El-Haggar
Omnia Aly
Amal F. Gharib
Amira I. Sayed
Heba Taha

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1710650

1,129 views

Opinion

Published on 06 Jan 2026

Some aspects of trypsin’s involvement in the regulation of physiological functions

in Protein Biochemistry for Basic and Applied Sciences

I. V. Kuzmina
S. M. Tolpygo
V. G. Vertiprakhov

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1750770

1,144 views

Editorial

Published on 05 Jan 2026

Editorial: Overcoming resistance in DDR inhibition: new targets and therapeutic strategies

in Molecular Diagnostics and Therapeutics

Chi-Lin Tsai
Ana Cristina Gonçalves
Zamal Ahmed

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1766744

917 views

Editorial

Published on 05 Jan 2026

Editorial: Cellular contributors and consequences of protein misfolding and aggregation

in Cellular Biochemistry

Anoop Arunagiri
Emily Sontag
Verena Kohler
Arunkumar Venkatesan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1759495

704 views

Original Research

Published on 05 Jan 2026

Garlic oil-loaded nanodisks for the amelioration of acute lung injury via modulation of the NF-κB and Keap1–Nrf2 axis

in Nanobiotechnology

Ruilin Hou
Bowen Jiang
Kai Wang
Xiaoying Yang
Wenping Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1686436

913 views

Original Research

Published on 05 Jan 2026

Glutamate enhances the production of inflammatory cytokines IL-6 and IL-11, as well as chemokines CXCL2, CXCL3, and CXCL8 in keloid fibroblasts

in Metabolomics

Yan Chen
Yaohan Xu
Jiahe Zhang
Chenxi Feng
Jie Chen
Yinjing Song
Jing Pan
Jiang Zhu
Hao Cheng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1720876

1,002 views

Original Research

Published on 02 Jan 2026

Mechanistic study of glutamine metabolic reprogramming driving non-small cell lung cancer progression via the FGF17-FGFR4 axis mediating epithelial-mesenchymal transition

in Molecular Diagnostics and Therapeutics

Qinghua Kong
Xiaoyan Wang
Wei Ding

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1728698

1,073 views

Original Research

Accepted on 29 Dec 2025

An Interpretability Heart Disease Prediction Model Based on Stacking Ensemble with SHAP

in Molecular Diagnostics and Therapeutics

Yanjie Chen
Liqiang Chong
Zhenghao Bao
Shaoqiang Wang
Yuchen Wang
Yanan Feng

Frontiers in Molecular Biosciences

278 views

Original Research

Accepted on 25 Dec 2025

The Endothelial Plasma Membrane Lipidome and its Remodeling under Hyperglycemia: an exploratory study

in Lipids, Membranes and Membranous Organelles

Ana Reis
Yahya Sohrabi
Lorena Sanchez
Ana Rita Araujo
Merle Leffers
Bruno Antonny
Alisa Rudnitskaya
Rui Vitorino
Irundika Dias

Frontiers in Molecular Biosciences

605 views

5,855 articles

articles

Editorial: Tumor-host interactions: metabolic and signaling pathways altered in cancer, immune and stromal cells

Differential roles for CLA-1L and UNC-10 in endosomal maturation and peptide release at C. elegans synapses impacting lifespan

Glycine attenuates sepsis-induced white matter injury by modulating gut microbiota

A novel prognostic model based on epithelial cell progression genes identifies OAS1 as a suppressor of bladder cancer aggressiveness

Research progress on oral glucagon-like peptide-1 receptor agonists in the treatment of diabetes mellitus type 2

Hypoxia-induced immunosuppression in uveal melanoma is mediated by CD63+ exosomes delivering lactate to reprogram immune cells

Cellular insights into transposable elements in Alzheimer’s disease

Forsythiaside a facilitates autophagy to ameliorate chronic nonbacterial prostatitis in rats by blocking the PKCα/NF-κB pathway

A diverse satellite DNA repertoire in Limnoperna fortunei: insights into genome structure and chromosomal organization

Pharmacophore modeling: advances and pitfalls

Effect of treatment duration on the associations between three modern antidiabetic drugs and survival outcomes of lung cancer in China

Herbal monomer–based therapeutic insights from traditional Chinese medicine in myocardial infarction

Nucleolus as a cornerstone linking proliferation and metabolism to cellular responses to stress: involvement of transcription factors MYC and p53

Advancing Trypanosoma cruzi N-myristoyltransferase as a drug target for Chagas disease through in silico discovery and biochemical evaluation

Strategies of AAV capsid engineering for targeted delivery to brain, muscle, and retina

Pyrrolopyrimidine derivatives as dual COX-2/ACE2 inhibitors: design, synthesis, and anti-inflammatory evaluation

Some aspects of trypsin’s involvement in the regulation of physiological functions

Editorial: Overcoming resistance in DDR inhibition: new targets and therapeutic strategies

Editorial: Cellular contributors and consequences of protein misfolding and aggregation

Garlic oil-loaded nanodisks for the amelioration of acute lung injury via modulation of the NF-κB and Keap1–Nrf2 axis

Glutamate enhances the production of inflammatory cytokines IL-6 and IL-11, as well as chemokines CXCL2, CXCL3, and CXCL8 in keloid fibroblasts

Mechanistic study of glutamine metabolic reprogramming driving non-small cell lung cancer progression via the FGF17-FGFR4 axis mediating epithelial-mesenchymal transition

An Interpretability Heart Disease Prediction Model Based on Stacking Ensemble with SHAP

The Endothelial Plasma Membrane Lipidome and its Remodeling under Hyperglycemia: an exploratory study