Frontiers in Molecular Biosciences | Genome Organization and Dynamics

Original Research

Accepted on 27 Aug 2025

Screening and Characterization of DNA Aptamers that Modulate Prime Editing

in Genome Organization and Dynamics

Mingxia Wang
Xinbo Huang
Jing Ye
Yaoting Gui

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1565459

237 views

Original Research

Accepted on 19 Aug 2025

Transcriptional stress in aging: integrating experimental data and modeling to quantify DNA damage accumulation

in Genome Organization and Dynamics

Jacinta van de Grint
Marko Raseta
Renata Maria Catharina Brandt
Yvette van Loon
Joris Demmers
Shannon Dealy
Jiang Chang
Jan Hoeijmakers
Joris Pothof

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1659589

188 views

Original Research

Accepted on 06 Aug 2025

Serovar-Specific Genomic Features of Leptospira interrogans Hardjo: Implications for Host Adaptation

in Genome Organization and Dynamics

Klaudia Dubniewicz
Laura Pardyak
Artur Gurgul
Igor Jasielczuk
Tomasz Szmatoła
Zbigniew Arent

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1648097

200 views

Original Research

Published on 12 May 2025

Ligand-receptor dynamics in heterophily-aware graph neural networks for enhanced cell type prediction from single-cell RNA-seq data

in Genome Organization and Dynamics

Lian Duan
Mahshad Hashemi
Alioune Ngom
Luis Rueda

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1547231

1,746 views

Review

Published on 28 Apr 2025

Type-2 diabetes epigenetic biomarkers: present status and future directions for global and Indigenous health

in Genome Organization and Dynamics

Sarah Munns
Alex Brown
Sam Buckberry

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1502640

2,022 views

Original Research

Published on 28 Feb 2025

Chromatin structure and gene transcription of recombinant p53 adenovirus vector within host

in Genome Organization and Dynamics

Duo Ning
Yuqing Deng
Simon Zhongyuan Tian

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1562357

1,278 views

Original Research

Published on 11 Dec 2024

Identification of key genes related to growth of largemouth bass (Micropterus salmoides) based on comprehensive transcriptome analysis

in Genome Organization and Dynamics

Dayan Hu
Jieliang Jian
Jinpeng Zhang
Xiaojun Xu
Shu Wang
Cuiping Gong
Yuanqin Zhang
Pengcan Zhu
Zhimin Gu
Wenzhi Guan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1499220

2,667 views
1 citation

Original Research

Published on 17 Oct 2024

Identification of immune microenvironment subtypes and clinical risk biomarkers for osteoarthritis based on a machine learning model

in Genome Organization and Dynamics

Bao Li
Yang Shen
Songbo Liu
Hong Yuan
Ming Liu
Haokun Li
Tonghe Zhang
Shuyuan Du
Xinwei Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1376793

2,491 views

Review

Published on 16 Oct 2024

Mutant ATRX: pathogenesis of ATRX syndrome and cancer

in Genome Organization and Dynamics

Kejia Yuan
Yan Tang
Zexian Ding
Lei Peng
Jinghua Zeng
Huaying Wu
Qi Yi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1434398

5,477 views
4 citations

Original Research

Published on 25 Sep 2024

Genome-wide association study for growth traits with 1066 individuals in largemouth bass (Micropterus salmoides)

in Genome Organization and Dynamics

Wei Han
Ming Qi
Kun Ye
Qiwei He
Dinaer Yekefenhazi
Dongdong Xu
Fang Han
Wanbo Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1443522

1,975 views
4 citations

Methods

Published on 22 Aug 2024

Obtention of viable cell suspensions from breast cancer tumor biopsies for 3D chromatin conformation and single-cell transcriptome analysis

in Genome Organization and Dynamics

Aura Stephenson-Gussinye
Luis A. Rendón-Bautista
Blanca E. Ruiz-Medina
Eduardo Blanco-Olais
Rosario Pérez-Molina
Cleofas Marcial-Medina
Yanin Chavarri-Guerra
Enrique Soto-Pérez-de-Celis
Andrea Morales-Alfaro
Ayerim Esquivel-López

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1420308

3,380 views
1 citation

Brief Research Report

Published on 25 Jul 2024

Analysis of genetic diversity among three Triplophysa tenuis populations by RAD-seq

in Genome Organization and Dynamics

Wenqiong Wu
Junqiang Qiu
Yue Lin
Xike Li
Wenjuan Li
Yuanliang Duan
Yuanshuai Fu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1373754

1,272 views

Original Research

Published on 11 Jul 2024

RNAi-dependent expression of sperm genes in ADL chemosensory neurons is required for olfactory responses in Caenorhabditis elegans

in Genome Organization and Dynamics

Maria C. Ow
Mailyn A. Nishiguchi
Abdul Rouf Dar
Rebecca A. Butcher
Sarah E. Hall

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1396587

2,633 views
1 citation

Brief Research Report

Published on 02 Jul 2024

Skeletal muscle feature of different populations in large yellow croaker (Larimichthys crocea): from an epigenetic point of view

in Genome Organization and Dynamics

Shangwei Xie
Lihua Jiang
Weihua Song
Jialang Zheng
Yifan Liu
Shun Chen
Xiaojun Yan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1403861

4,100 views
2 citations

Original Research

Published on 15 Apr 2024

PhbZIP2 regulates photosynthesis-related genes in an intertidal macroalgae, Pyropia haitanensis, under stress

in Genome Organization and Dynamics

Han Zhang
Gaoxiong Zeng
Jiajia Xie
Yichi Zhang
Dehua Ji
Yan Xu
Chaotian Xie
Wenlei Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1345585

1,646 views
1 citation

Original Research

Published on 11 Apr 2024

A delayed and unsynchronized ovary development as revealed by transcriptome of brain and pituitary of Coilia nasus

in Genome Organization and Dynamics

Ziyan Yu
Zongshuai Gao
Yun Zeng
Mingyou Li
Gangchun Xu
Mingchun Ren
Yunxia Zhu
Dong Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1361386

1,872 views
2 citations