Frontiers in Molecular Biosciences | Genome Organization and Dynamics

Original Research

Accepted on 23 Sep 2025

Mapping of Chromatin Architecture and Enhancer-Promoter Interactions in the Cochlea

in Genome Organization and Dynamics

Tuba Ege
Celia R Bloom
Mi Zhou
Huizhan Liu
Litao Tao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1683964

476 views

Original Research

Published on 10 Sep 2025

Serovar-specific genomic features of Leptospira interrogans Hardjo: implications for host adaptation

in Genome Organization and Dynamics

Klaudia Dubniewicz
Laura Pardyak
Artur Gurgul
Igor Jasielczuk
Tomasz Szmatoła
Zbigniew J. Arent

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1648097

1,800 views

Original Research

Published on 09 Sep 2025

Screening and characterization of DNA aptamers that modulate prime editing

in Genome Organization and Dynamics

Mingxia Wang
Xia Wu
Xinbo Huang
Jing Ye
Yaoting Gui

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1565459

2,219 views

Original Research

Published on 08 Sep 2025

Transcriptional stress in aging: integrating experimental data and modeling to quantify DNA damage accumulation

in Genome Organization and Dynamics

Jacinta van de Grint
Marko Raseta
Renata Brandt
Yvette van Loon
Joris Demmers
Shannon Dealy
Jiang Chang
Jan Hoeijmakers
Joris Pothof

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1659589

2,087 views

Original Research

Published on 12 May 2025

Ligand-receptor dynamics in heterophily-aware graph neural networks for enhanced cell type prediction from single-cell RNA-seq data

in Genome Organization and Dynamics

Lian Duan
Mahshad Hashemi
Alioune Ngom
Luis Rueda

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1547231

2,293 views

Review

Published on 28 Apr 2025

Type-2 diabetes epigenetic biomarkers: present status and future directions for global and Indigenous health

in Genome Organization and Dynamics

Sarah Munns
Alex Brown
Sam Buckberry

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1502640

2,357 views

Original Research

Published on 28 Feb 2025

Chromatin structure and gene transcription of recombinant p53 adenovirus vector within host

in Genome Organization and Dynamics

Duo Ning
Yuqing Deng
Simon Zhongyuan Tian

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1562357

1,486 views

Original Research

Published on 11 Dec 2024

Identification of key genes related to growth of largemouth bass (Micropterus salmoides) based on comprehensive transcriptome analysis

in Genome Organization and Dynamics

Dayan Hu
Jieliang Jian
Jinpeng Zhang
Xiaojun Xu
Shu Wang
Cuiping Gong
Yuanqin Zhang
Pengcan Zhu
Zhimin Gu
Wenzhi Guan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1499220

2,911 views
1 citation

Original Research

Published on 17 Oct 2024

Identification of immune microenvironment subtypes and clinical risk biomarkers for osteoarthritis based on a machine learning model

in Genome Organization and Dynamics

Bao Li
Yang Shen
Songbo Liu
Hong Yuan
Ming Liu
Haokun Li
Tonghe Zhang
Shuyuan Du
Xinwei Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1376793

2,806 views

Review

Published on 16 Oct 2024

Mutant ATRX: pathogenesis of ATRX syndrome and cancer

in Genome Organization and Dynamics

Kejia Yuan
Yan Tang
Zexian Ding
Lei Peng
Jinghua Zeng
Huaying Wu
Qi Yi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1434398

6,228 views
4 citations

Original Research

Published on 25 Sep 2024

Genome-wide association study for growth traits with 1066 individuals in largemouth bass (Micropterus salmoides)

in Genome Organization and Dynamics

Wei Han
Ming Qi
Kun Ye
Qiwei He
Dinaer Yekefenhazi
Dongdong Xu
Fang Han
Wanbo Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1443522

2,245 views
4 citations

Methods

Published on 22 Aug 2024

Obtention of viable cell suspensions from breast cancer tumor biopsies for 3D chromatin conformation and single-cell transcriptome analysis

in Genome Organization and Dynamics

Aura Stephenson-Gussinye
Luis A. Rendón-Bautista
Blanca E. Ruiz-Medina
Eduardo Blanco-Olais
Rosario Pérez-Molina
Cleofas Marcial-Medina
Yanin Chavarri-Guerra
Enrique Soto-Pérez-de-Celis
Andrea Morales-Alfaro
Ayerim Esquivel-López

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1420308

3,789 views
1 citation

Brief Research Report

Published on 25 Jul 2024

Analysis of genetic diversity among three Triplophysa tenuis populations by RAD-seq

in Genome Organization and Dynamics

Wenqiong Wu
Junqiang Qiu
Yue Lin
Xike Li
Wenjuan Li
Yuanliang Duan
Yuanshuai Fu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1373754

1,439 views

Original Research

Published on 11 Jul 2024

RNAi-dependent expression of sperm genes in ADL chemosensory neurons is required for olfactory responses in Caenorhabditis elegans

in Genome Organization and Dynamics

Maria C. Ow
Mailyn A. Nishiguchi
Abdul Rouf Dar
Rebecca A. Butcher
Sarah E. Hall

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1396587

2,879 views
1 citation

Brief Research Report

Published on 02 Jul 2024

Skeletal muscle feature of different populations in large yellow croaker (Larimichthys crocea): from an epigenetic point of view

in Genome Organization and Dynamics

Shangwei Xie
Lihua Jiang
Weihua Song
Jialang Zheng
Yifan Liu
Shun Chen
Xiaojun Yan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1403861

4,394 views
2 citations

Original Research

Published on 15 Apr 2024

PhbZIP2 regulates photosynthesis-related genes in an intertidal macroalgae, Pyropia haitanensis, under stress

in Genome Organization and Dynamics

Han Zhang
Gaoxiong Zeng
Jiajia Xie
Yichi Zhang
Dehua Ji
Yan Xu
Chaotian Xie
Wenlei Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1345585

1,849 views
1 citation