Frontiers in Molecular Biosciences | Genome Organization and Dynamics

Original Research

Published on 07 Mar 2024

Proband-independent haplotyping based on NGS-based long-read sequencing for detecting pathogenic variant carrier status in preimplantation genetic testing for monogenic diseases

in Genome Organization and Dynamics

Peiyu Zhang
Xiaomei Zhao
Qinshan Li
Yaqiong Xu
Zengmei Cheng
Lu Yang
Houmei Wang
Yang Tao
Guanyou Huang
Rui Wu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1329580

4,396 views
8 citations

Hypothesis and Theory

Published on 22 Feb 2024

Transposable elements as scaffold/matrix attachment regions: shaping organization and functions in genomes

in Genome Organization and Dynamics

Rashmi Upadhyay Pathak
Kundurthi Phanindhar
Rakesh K. Mishra

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1326933

4,170 views
4 citations

Original Research

Published on 05 Feb 2024

CCN3, POSTN, and PTHLH as potential key regulators of genomic integrity and cellular survival in iPSCs

in Genome Organization and Dynamics

Nuha T. Swaidan
Nada H. Soliman
Ahmed T. Aboughalia
Toqa Darwish
Ruba O. Almeshal
Azhar A. Al-Khulaifi
Rowaida Z. Taha
Rania Alanany
Ahmed Y. Hussein
Salam Salloum-Asfar

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1342011

3,005 views

Original Research

Published on 08 Jan 2024

Alteration of the −35 and −10 sequences and deletion the upstream sequence of the −35 region of the promoter A1 of the phage T7 in dsDNA confirm the contribution of non-specific interactions with E. coli RNA polymerase to the transcription initiation process

in Genome Organization and Dynamics

Katarzyna Turecka
Małgorzata Firczuk
Władysław Werel

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1335409

4,367 views
4 citations

Original Research

Published on 04 Dec 2023

Hydrogen bonding in duplex DNA probed by DNP enhanced solid-state NMR N-H bond length measurements

in Genome Organization and Dynamics

Lakshmi Bhai
Justin K. Thomas
Daniel W. Conroy
Yu Xu
Hashim M. Al-Hashimi
Christopher P. Jaroniec

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1286172

4,024 views
8 citations

Review

Published on 24 Nov 2023

Telomere maintenance in African trypanosomes

in Genome Organization and Dynamics

Bibo Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1302557

3,663 views
3 citations

Mini Review

Published on 15 Nov 2023

The consequences of cohesin mutations in myeloid malignancies

in Genome Organization and Dynamics

Shubhra Ashish Bhattacharya
Eve Dias
Andrea Nieto-Aliseda
Marcus Buschbeck

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1319804

4,856 views

Review

Published on 31 Oct 2023

Noncoding rules of survival: epigenetic regulation of normal and malignant hematopoiesis

in Genome Organization and Dynamics

LaShanale Wallace
Esther A. Obeng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1273046

5,295 views
6 citations

Opinion

Published on 26 Oct 2023

The emerging field of opportunities for single-cell DNA methylation studies in hematology and beyond

in Genome Organization and Dynamics

Leone Albinati
Agostina Bianchi
Renée Beekman

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1286716

3,954 views

Original Research

Published on 17 Oct 2023

A genotype–phenotype correlation in split-hand/foot malformation type 1: further refinement of the phenotypic subregions within the 7q21.3 locus

in Genome Organization and Dynamics

Anna Sowińska-Seidler
Magdalena Socha
Anna Szoszkiewicz
Anna Materna-Kiryluk
Aleksander Jamsheer

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1250714

4,304 views

Original Research

Published on 12 Oct 2023

A first draft genome of holm oak (Quercus ilex subsp. ballota), the most representative species of the Mediterranean forest and the Spanish agrosylvopastoral ecosystem “dehesa”

in Genome Organization and Dynamics

María-Dolores Rey
Mónica Labella-Ortega
Víctor M. Guerrero-Sánchez
Rômulo Carleial
María Ángeles Castillejo
Valentino Ruggieri
Jesús V. Jorrín-Novo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1242943

5,384 views
16 citations

Review

Published on 10 Oct 2023

Understanding blood development and leukemia using sequencing-based technologies and human cell systems

in Genome Organization and Dynamics

Branco M. H. Heuts
Joost H. A. Martens

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1266697

4,232 views
1 citation

Review

Published on 09 Oct 2023

Chromatin: the old and young of it

in Genome Organization and Dynamics

Felicity J. Emerson
Siu Sylvia Lee

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1270285

7,965 views
11 citations

Original Research

Published on 31 Aug 2023

Allosteric activation of RhlB by RNase E induces partial duplex opening in substrate RNA

in Genome Organization and Dynamics

Heidi Zetzsche
Laura Raschke
Boris Fürtig

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1139919

2,427 views
2 citations

Original Research

Published on 01 Aug 2023

Uncovering the role of Rad51 in homologous recombination-mediated antigenic diversification in the human malaria parasite Plasmodium falciparum

in Genome Organization and Dynamics

Pratap Vydyam
Nabamita Roy
Mrinal Kanti Bhattacharyya

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1223682

2,449 views
3 citations

Review

Published on 04 Jul 2023

CRISPR/Cas9 as a therapeutic tool for triple negative breast cancer: from bench to clinics

in Genome Organization and Dynamics

Prashant Kumar Tiwari
Tin-Hsien Ko
Rajni Dubey
Mandeep Chouhan
Lung-Wen Tsai
Himanshu Narayan Singh
Kundan Kumar Chaubey
Deen Dayal
Chih-Wei Chiang
Sanjay Kumar

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1214489

18,687 views
25 citations

Editorial

Published on 22 Jun 2023

Editorial: Highly resolved spatio-temporal dynamics of genome organization and its link with transcriptional dynamics editorial

in Genome Organization and Dynamics

Rajarshi P. Ghosh

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1213345

2,112 views

Original Research

Published on 14 Jun 2023

A CRISPR-based approach using dead Cas9-sgRNA to detect SARS-CoV-2

in Genome Organization and Dynamics

Mustapha Aouida
Maryam Saifaldeen
Dana E. Al-Ansari
Sara Taleb
Ali Ait Hssain
Dindial Ramotar

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1201347

5,484 views
4 citations

Review

Published on 14 Jun 2023

Genomic and pathogenicity islands of Listeria monocytogenes—overview of selected aspects

in Genome Organization and Dynamics

Natalia Wiktorczyk-Kapischke
Krzysztof Skowron
Ewa Wałecka-Zacharska

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1161486

29,937 views
58 citations

Review

Published on 08 Jun 2023

Episomal and chromosomal DNA replication and recombination in Entamoeba histolytica

in Genome Organization and Dynamics

Sudha Bhattacharya

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1212082

4,758 views
3 citations

Review

Published on 05 Apr 2023

Considerations and caveats for analyzing chromatin compartments

in Genome Organization and Dynamics

Achyuth Kalluchi
Hannah L. Harris
Timothy E. Reznicek
M. Jordan Rowley

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1168562

9,919 views
17 citations

Mini Review

Published on 31 Mar 2023

Advances and challenges in CRISPR-based real-time imaging of dynamic genome organization

in Genome Organization and Dynamics

Jenna Thuma
Yu-Chieh Chung
Li-Chun Tu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1173545

6,153 views
9 citations

Perspective

Published on 27 Mar 2023

Women’s contribution in understanding how topoisomerases, supercoiling, and transcription control genome organization

in Genome Organization and Dynamics

Laura Martin
Maria Victoria Neguembor
Maria Pia Cosma

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1155825

4,102 views

Review

Published on 27 Mar 2023

Progress in 7SK ribonucleoprotein structural biology

in Genome Organization and Dynamics

Momodou B. Camara
Amr M. Sobeh
Catherine D. Eichhorn

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1154622

7,994 views
7 citations

60 articles

articles

Proband-independent haplotyping based on NGS-based long-read sequencing for detecting pathogenic variant carrier status in preimplantation genetic testing for monogenic diseases

Transposable elements as scaffold/matrix attachment regions: shaping organization and functions in genomes

CCN3, POSTN, and PTHLH as potential key regulators of genomic integrity and cellular survival in iPSCs

Alteration of the −35 and −10 sequences and deletion the upstream sequence of the −35 region of the promoter A1 of the phage T7 in dsDNA confirm the contribution of non-specific interactions with E. coli RNA polymerase to the transcription initiation process

Hydrogen bonding in duplex DNA probed by DNP enhanced solid-state NMR N-H bond length measurements

Telomere maintenance in African trypanosomes

The consequences of cohesin mutations in myeloid malignancies

Noncoding rules of survival: epigenetic regulation of normal and malignant hematopoiesis

The emerging field of opportunities for single-cell DNA methylation studies in hematology and beyond

A genotype–phenotype correlation in split-hand/foot malformation type 1: further refinement of the phenotypic subregions within the 7q21.3 locus

A first draft genome of holm oak (Quercus ilex subsp. ballota), the most representative species of the Mediterranean forest and the Spanish agrosylvopastoral ecosystem “dehesa”

Understanding blood development and leukemia using sequencing-based technologies and human cell systems

Chromatin: the old and young of it

Allosteric activation of RhlB by RNase E induces partial duplex opening in substrate RNA

Uncovering the role of Rad51 in homologous recombination-mediated antigenic diversification in the human malaria parasite Plasmodium falciparum

CRISPR/Cas9 as a therapeutic tool for triple negative breast cancer: from bench to clinics

Editorial: Highly resolved spatio-temporal dynamics of genome organization and its link with transcriptional dynamics editorial

A CRISPR-based approach using dead Cas9-sgRNA to detect SARS-CoV-2

Genomic and pathogenicity islands of Listeria monocytogenes—overview of selected aspects

Episomal and chromosomal DNA replication and recombination in Entamoeba histolytica

Considerations and caveats for analyzing chromatin compartments

Advances and challenges in CRISPR-based real-time imaging of dynamic genome organization

Women’s contribution in understanding how topoisomerases, supercoiling, and transcription control genome organization

Progress in 7SK ribonucleoprotein structural biology