Frontiers in Molecular Biosciences

Original Research

Published on 12 Jun 2025

Blood metabolome shows signatures of metabolic dysregulation in obese and overweight subjects that can be predicted by machine learning applied to heart rate variability

in Metabolomics

Andrea Di Credico
David Perpetuini
Pascal Izzicupo
Giulia Gaggi
Claudia Rossi
Arcangelo Merla
Barbara Ghinassi
Angela Di Baldassarre
Ines Bucci

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1561987

314 views

Original Research

Accepted on 11 Jun 2025

Non-Targeted Metabolomics and Network Pharmacology of Taohong Siwu Decoction in Hepatic Fibrosis Mouse Model Using High Resolution Mass Spectrometry

in Metabolomics

Shengsheng Li
Shenglan Qi
Rongsheng Li
Fangming Yang
Zhenyi Niu
Wei Liu
Suping Ma
Zhun Xiao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1614341

Original Research

Published on 04 Jun 2025

Cold-induced biochemical changes in leaves of two commercial clones of Eucalyptus

in Metabolomics

Patricia Basile
Federico Wallace
Cristina Olivaro
Nicolás De Palma
Omar Borsani
Arthur Fett-Neto

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1584132

398 views

Editorial

Published on 04 Jun 2025

Editorial: Current trends in targeted and non-targeted metabolomics in analytical toxicology

in Metabolomics

Geraldine M. Dowling
Markus R. Meyer

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1614399

460 views

Original Research

Accepted on 30 May 2025

Untargeted Metabolomics Fingerprints in Seminal Plasma of Patients with Abnormal Sperm Morphology using High-Performance Liquid Chromatography and Mass Spectrometry

in Metabolomics

Serena Correnti
Giuseppina Fanelli
Mariaimmacolata Preiano'
Veronica Lelli
Mariagrazia Tarantino
Annalisa Fregola
Massimo Bitonti
Emanuela Chiarella
Anna Maria Timperio
Sara Rinalducci

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1578998

148 views

Original Research

Published on 30 May 2025

Clinical metabolomics reveals potential diagnostic biomarkers in serum samples from patients with generalized ligamentous laxity

in Metabolomics

Yu Zhang
Xiaochao Hu
Feng Chen
Tongtong Liu
Ping Cai
Shijia Liu
Luning Sun

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1554936

557 views

Original Research

Published on 30 May 2025

Multi-omics analysis of flavor differences in pectoral muscles between Wuqin 10 duck and Cherry valley duck

in Metabolomics

Ping Gong
Shengqiang Ye
Xing Chen
Lixia Wang
Yunguo Qian
Mingli Zhai
Yu Yang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1558907

558 views

Brief Research Report

Accepted on 27 May 2025

Unveiling the Influence of Caffeine on Topiramate: Metabolomic Marker Analysis using Liquid Chromatography-Mass Spectrometry

in Metabolomics

Adrian Bartoszek
Ewa Paszkowska
Anna Kozub-Pędrak
Agata Sumara
Emilia Fornal

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1549993

175 views

Original Research

Accepted on 27 May 2025

Untargeted Plasma Metabolite Detection in Sudden Sensorineural Hearing Loss: Identifying Key Metabolic Signatures

in Metabolomics

Huangruici Zhang
Rongyue Ma
Weijie Wang
Changping Yu
Xiong Guohang
Qing Li
Yan Wang
Li Zhou
Yu Zhang
Min Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1567064

178 views

Original Research

Accepted on 22 May 2025

Global Trends and Emerging Insights in Ocular Tumor-Associated Metabolites: A Bibliometric and Visualization Analysis

in Metabolomics

Subo Cai
Wuping Xu
Dongyi Yu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1572710

182 views

Original Research

Accepted on 21 May 2025

Comprehensive Clinical and Metabolomics Profiling of COVID-19 Mexican Patients Across Three Epidemiological Waves

in Metabolomics

David Alejandro García-López
Joel Monárrez-Espino
Juan Carlos Borrego
Jiamin Zheng
Rupasri Mandal
Claudia Torres-Calzada
Juan Jose Oropeza Valdez
Alanne Tenório Nunes
Sergio Hugo Sánchez Rodríguez
Jesús Adrián López

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1607583

303 views

Original Research

Published on 16 May 2025

Metabolic reprogramming signature predicts prognosis and immune landscape in small cell lung cancer: MOCS2 validation and implications for personalized therapy

in Metabolomics

Junyan Wang
Panpan Sun
Fan Zhang
Yu Xu
Shenghu Guo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1592888

1,032 views

Original Research

Published on 09 May 2025

Metabolic insights into hypoxia adaptation in adolescent athletes at different altitudes: a cross-sectional study

in Metabolomics

Carlos A. R. Sánchez
Daniel Pardo-Rodriguez
Erica Mancera-Soto
Lizeth León
Dailson Paulucio
Angelo D’Alessandro
Caleb G. M. Santos
Edgar Cristancho
Gustavo Monnerat
Diana M. Ramos-Caballero

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1571103

1,223 views

Original Research

Published on 08 May 2025

Untargeted metabolomics for acute intra-abdominal infection diagnosis in serum and urine using UHPLC-TripleTOF MS

in Metabolomics

Zhenhua Dong
Shaopeng Zhang
Hongwei Zhang
Dingliang Zhao
Ziwen Pan
Daguang Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1534102

927 views

Original Research

Published on 30 Apr 2025

Cuscutae Semen in depression-induced ovarian dysfunction: metabolomics with UPLC-QToF-MS in female mice

in Metabolomics

Ying Xie
Zhaoxiang Zeng
Jinrong Zhang
Qiangqiang Han
Chengwu Song
Shuna Jin
Min Zhao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1595602

1,254 views

Original Research

Published on 28 Apr 2025

MS4A7 based metabolic gene signature as a prognostic predictor in lung adenocarcinoma

in Metabolomics

Yan Jiang
Zhengyu Shu
Lei Cheng
Haowei Wang
Taiping He
Liwen Fu
Chao Zhao
Xuefei Li
Weicheng Zeng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1591446

1,437 views