Frontiers in Molecular Biosciences

Review

Published on 23 Oct 2025

High-resolution protein modeling through Cryo-EM and AI: current trends and future perspectives – a review

in Structural Biology

Gnanaprakash Jeyaraj
Anith Kumar Rajendran
Kuppusamy Sathishkumar
Bader O. Almutairi
Aanand Vadivelu
Santosh Chokkakula
Yanyang Tu
Weimim Xie

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1688455

1,015 views

Review

Accepted on 15 Oct 2025

Molecular mechanisms and computational insights into human SGLTs: advancing toward selective SGLT1 inhibition

in Structural Biology

Nadhiri Kaijage
Sebastian Kraszewski

Frontiers in Molecular Biosciences

143 views

Correction

Accepted on 06 Oct 2025

Correction: Dihedral Angle Measurements for Structure Determination by Biomolecular Solid-State NMR Spectroscopy

in Structural Biology

Patrick C.A. Van der Wel

Frontiers in Molecular Biosciences

136 views

Original Research

Published on 24 Sep 2025

Interactions between membrane-bound streptococcal alpha-enolase and human plasminogen captured through cryogenic-electron microscopy

in Structural Biology

Sheiny Tjia-Fleck
Bradley M. Readnour
Zhong Liang
Yetunde A. Ayinuola
Francis J. Castellino

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1666748

1,767 views

Correction

Published on 08 Sep 2025

Correction: Editorial: Structural studies of bacteria and viruses

in Structural Biology

Frontiers Production Office

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1697351

1,152 views

Editorial

Published on 24 Jun 2025

Editorial: Methodological advancements and improvements in structural biology

in Structural Biology

Annalisa Pastore

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1625111

1,494 views

Editorial

Published on 30 Apr 2025

Editorial: Structural studies of bacteria and viruses

in Structural Biology

Annalisa Pastore

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1605596

1,578 views

Original Research

Published on 16 Apr 2025

Structure-guided virtual screening reveals phytoconstituents as potent cathepsin B inhibitors: Implications for cancer, traumatic brain injury, and Alzheimer’s disease

in Structural Biology

Nageeb Hassan
Mohammad Furkan
Mohd Shahnawaz Khan
Azna Zuberi
Moyad Shahwan
Anas Shamsi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1581711

2,137 views
2 citations

Brief Research Report

Published on 16 Apr 2025

In silico characterization of the interaction of AKR1B1 with the deacetylase activation domain (DAD)

in Structural Biology

Francisco J. Gómez-Zaldívar
Luis Córdova-Bahena
Angel J. Ruiz-Moreno
Paolo Ceppi
Marco A. Velasco-Velázquez

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1562206

1,878 views

Original Research

Published on 31 Mar 2025

Highly conserved ion binding sites are not all functionally relevant in mouse KCC4

in Structural Biology

Lisa Becker
Jens Hausmann
Rieke Wellpott
Anna-Maria Hartmann

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1556250

1,411 views

Original Research

Published on 10 Mar 2025

Computational electrostatic engineering of nanobodies for enhanced SARS−CoV−2 receptor binding domain recognition

in Structural Biology

Zafar Iqbal
Muhammad Asim
Umair Ahmad Khan
Neelam Sultan
Irfan Ali

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1512788

2,958 views

Correction

Published on 28 Nov 2024

Corrigendum: Shedding light on the DICER1 mutational spectrum of uncertain significance in malignant neoplasms

in Structural Biology

D. S. Bug
I. S. Moiseev
Yu. B. Porozov
N. V. Petukhova

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1517143

962 views

Editorial

Published on 16 Oct 2024

Editorial: Cryogenic electron microscopy of infectious diseases

in Structural Biology

Jiho Yoo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1506197

1,640 views
1 citation

Original Research

Published on 15 Oct 2024

Identification of potential bioactive phytochemicals for the inhibition of platelet-derived growth factor receptor β: a structure-based approach for cancer therapy

in Structural Biology

Insan Habib
Md Nayab Sulaimani
Deeba Shamim Jairajpuri
Afzal Hussain
Taj Mohammad
Mohamed F. Alajmi
Anas Shamsi
Md Imtaiyaz Hassan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1492847

2,816 views
3 citations

Original Research

Published on 03 Oct 2024

Shedding light on the DICER1 mutational spectrum of uncertain significance in malignant neoplasms

in Structural Biology

D. S. Bug
I. S. Moiseev
Yu. B. Porozov
N. V. Petukhova

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1441180

2,383 views
2 citations

Original Research

Published on 01 Oct 2024

Semantic segmentation-based detection algorithm for challenging cryo-electron microscopy RNP samples

in Structural Biology

J. Vargas
A. Modrego
H. Canabal
J. Martin-Benito

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1473609

1,741 views
1 citation