Frontiers in Molecular Neuroscience

Original Research

Accepted on 26 Sep 2025

PGC-1α promotes the survival of newborn neurons within AD hippocampus through activation of the FNDC5/BDNF/TrkB signaling pathway

in Neuroplasticity and Development

Yi-Jie Wang
Yu-Xin Wang
Wei-Jun Zhang
Wen Pan
Jia-Qing Wang
Hua Wang
Xin Qian
Feng-Guo Liu
Jia Wang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1688694

144 views

Correction

Published on 26 Sep 2025

Correction: Neuroprotective effects of the pannexin-1 channel inhibitor: probenecid on spinal cord injury in rats

in Neuroplasticity and Development

Qi Qi
Xiao-Xuan Wang
Jing-Lu Li
Yu-Qing Chen
Jian-Rong Chang
Jin Xi
He-Zuo Lü
Yu-Xin Zhang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1698001

802 views

Review

Accepted on 25 Sep 2025

Ferroptosis as a potential therapeutic target for post-traumatic stress disorder

in Brain Disease Mechanisms

Qian Zhang
Jin-Dong Mao
Hui Chen
Min Wang
Yu-Mei Wu
Chuan Wang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1648047

1,199 views

Review

Accepted on 25 Sep 2025

Peripheral–Central Immune Interactions in Parkinson's Disease: Insights into Innate and Adaptive Immunity

in Brain Disease Mechanisms

Jarika Jahan Tumpa
Qurat Ul Ain Hayder
Nowshin sharmily Maisa
Md. Nazmul Islam

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1682006

240 views

Review

Published on 25 Sep 2025

TRP channels in epileptogenesis: calcium dysregulation mechanisms and pharmacological targeting strategies

in Brain Disease Mechanisms

Guolong Deng
Dayuan Liu
Yunxiang Zhong
Muyao Wang
Baoshou Su
Hongli Jiang
Yihao Zhai
Hao Peng
Caicai Zhang
Jigao Feng

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1687359

859 views

Review

Accepted on 23 Sep 2025

Bridging Prion Biology and Alzheimer's Disease: From Pathogenic Seeds to Precision Therapeutics

in Brain Disease Mechanisms

Wenjin Wang
Zhan-hui Feng
Luofeng Luofeng
Yongmei Hu
Yuting Chen
Baihui Zhang
Hua Huang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1660151

243 views

Original Research

Accepted on 23 Sep 2025

Schizophrenia Risk Gene ZNF536 modulates Retinoic Acid Response and Neuronal Gene Networks in SH-SY5Y Cells

in Methods and Model Organisms

Artemiy O. Kurishev
Dmitrii A. Abashkin
Dmitry S. Karpov
Ekaterina V. Marilovtseva
Yulia A. Chaika
Ekaterina V. Semina
Vera E. Golimbet

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1671354

230 views

Original Research

Published on 22 Sep 2025

Cross-disease biomarker identification reveals shared diagnostic biomarkers for IVDD and NAFLD via bulk and single-cell RNA sequencing

in Molecular Signalling and Pathways

Jiasen Wei
Chenglong Ji
Lina Liu
Chen Yan
Linhui Han
Wenbo Lin
Ximing Xu
Kaiqiang Sun

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1639705

752 views

Review

Published on 22 Sep 2025

Advances in research on propofol-induced postoperative cognitive dysfunction via Piezo channels

in Molecular Signalling and Pathways

Han Xue
Xiaoyu Zhang
Chenxu Chou
Yulong Jia
Chunguang Hao
Xiaguang Duan

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1668523

1,030 views

Editorial

Published on 22 Sep 2025

Editorial: Innovative approaches in glioma therapy: exploring new therapeutic frontiers

in Brain Disease Mechanisms

Pilar Marcos
Arturo Mangas
Rafael Coveñas

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1697606

953 views

Mini Review

Accepted on 19 Sep 2025

Neurochemical Crossroads: Exploring the Neurotransmitter Network in Chronic Pain and Depression Comorbidity

in Pain Mechanisms and Modulators

Min Ma
Yue Zhang
Kunming Tao
Zhijie Lu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1675814

453 views

Original Research

Accepted on 18 Sep 2025

SIRT3 inhibits autophagy-dependent ferroptosis of HUVECs in the progression of pregnancy-induced hypertension by activating the PI3K/Akt/mTOR axis

in Molecular Signalling and Pathways

Yanchuan Li
Yanfeng Liu
Ziyun Shi
Meiqing He

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1620184

456 views

Correction

Accepted on 18 Sep 2025

Correction: Endoglin alleviates neuropathic pain by protecting the blood–spinal cord barrier through the TGF-β/Smad2 signaling pathway

in Pain Mechanisms and Modulators

SiJing Liao
Fei-Ran Zhou
Qun Li
Tao Jin
Gui-Fang Xiang
Xin Wang
Yan Liu
Hq Zhu
Qing Liu
Yuexin Liu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1707410

481 views

Mini Review

Accepted on 17 Sep 2025

Food for Thought: Probiotic Modulation of Microglial Activity in Parkinson's Disease

in Brain Disease Mechanisms

Isabella Kroker Kimber
Marie-Ève Tremblay

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1690507

641 views

Original Research

Published on 15 Sep 2025

Tamoxifen attenuates manganese-induced dysregulation of neuronal REST via the genomic ER-α mechanism

in Molecular Signalling and Pathways

Alexis Digman
Edward Pajarillo
Sanghoon Kim
Itunu Ajayi
Deok-Soo Son
Michael Aschner
Eunsook Lee

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1648904

1,190 views

Original Research

Published on 15 Sep 2025

Endoglin alleviates neuropathic pain by protecting the blood–spinal cord barrier through the TGF-β/Smad2 signaling pathway

in Pain Mechanisms and Modulators

SiJing Liao
Fei-Ran Zhou
Qun Li
Tao Jin
Gui-Fang Xiang
Xin Wang
Yan Liu
Hq Zhu
Qing Liu
Yuexin Liu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1603619

1,296 views