Frontiers in Molecular Neuroscience | Molecular Signalling and Pathways

Original Research

Published on 17 Jul 2025

Tet3-mediated DNA demethylation is essential for maintaining the dedifferentiation capacity of mammalian Müller glia

in Molecular Signalling and Pathways

Erick J. Martinez-Colin
Ivonne Lezama
Lenin D. Ochoa-de la Paz
Monica Lamas

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1628860

345 views

Editorial

Accepted on 15 Jul 2025

Editorial - Pathobiological Defects in Sensorineural Hearing Loss: From Identification to Rescue

in Molecular Signalling and Pathways

Emanuele Bernardinelli
Laura Astolfi
Konstantina Stankovic

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1654457

162 views

Review

Accepted on 14 Jul 2025

Silencing Epileptic Storms: Targeting miRNA-lncRNA Crosstalk in Astrocytes and Microglia to Disarm Neuroinflammatory Triggers

in Molecular Signalling and Pathways

Jing Meng
Wen Luo
Nana Zhang
Mingxing Yu
Yuxuan He
Chunyan Chen
Haifeng Shu
Yu Liang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1616804

Review

Accepted on 08 Jul 2025

Sonic Hedgehog Signaling in Spinal Cord Injury: Mechanisms and Therapeutic Implications

in Molecular Signalling and Pathways

Mingjuan Du
Weiting Chen
Xiaozhen Ji

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1624501

144 views

Original Research

Published on 08 Jul 2025

Peripheral gene dysregulation in Negr1-deficient mice: insights into possible links with affective behavior

in Molecular Signalling and Pathways

Abdulkadir Yusif Maigoro
Jangrae Kim
Seoyeon Cho
Ara Yoo
Soojin Lee

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1602201

511 views

Mini Review

Accepted on 07 Jul 2025

LncRNA-driven programmed cell death networks: New therapeutic targets for neurological disorders

in Molecular Signalling and Pathways

Shiyong Huang
Xiong Zihong
Chao sun

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1635119

103 views

Review

Published on 04 Jul 2025

TRP channels in mammalian hearing loss

in Molecular Signalling and Pathways

Zhidong Zhang
Baoshan Wang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1626640

413 views

Review

Published on 02 Jul 2025

The neurological pathology of peroxisomal ACBD5 deficiency – lessons from patients and mouse models

in Molecular Signalling and Pathways

Michael L. Dawes
Jim P. Haberlander
Markus Islinger
Michael Schrader

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1602343

694 views

Original Research

Published on 26 Jun 2025

The potential anti-seizure effects of Astaxanthin-loaded nanostructured lipid carriers in rat model of status epilepticus

in Molecular Signalling and Pathways

Sherien E. Khalaf
Mohammad Al Masri
Ghaleb Oriquat
Maher A. Kamel
Nagwa M. Assem
Suzan M. Abdel-Tawab
Samar S. Elblehi
Shimaa A. Mahmoud

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1613893

800 views

Original Research

Published on 23 Jun 2025

Exploring research trends and hotspots in PI3K/Akt signaling pathway in ischemic stroke: a bibliometric analysis

in Molecular Signalling and Pathways

Yingquan Liu
Yu Ye
Lin Bai
Fan Dai
Xingxing Su
Peijia Hu
Hongliang Cheng

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1613702

1,109 views

Review

Published on 20 Jun 2025

Peroxisome dynamics and inter-organelle interactions in neuronal health and disease

in Molecular Signalling and Pathways

Ruth E. Carmichael

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1603632

1,125 views

Original Research

Published on 20 Jun 2025

Silencing ATF3 mediates mitochondrial homeostasis and improves ischemic stroke through regulating the MAPK signaling pathway

in Molecular Signalling and Pathways

Haifengqing Li
Fan Zhang
Cong Zhang
Min Zhou
Qing Liu
Guoyong Zeng

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1554802

752 views

Original Research

Published on 19 Jun 2025

Dysregulation of heterochromatin caused by genomic structural variants may be central to autism spectrum disorder

in Molecular Signalling and Pathways

Michael R. Garvin
David Kainer

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1553575

1,124 views

Brief Research Report

Published on 18 Jun 2025

Inhibition of class IIa HDACs reduces mutant HTT aggregation by affecting RNA stability

in Molecular Signalling and Pathways

Annika Reisbitzer
Cecilia Hollitzer
Adriana Geraci
Jessye Schaefer
Maximilian Burghaus
Jonas Bruns
Joachim Urban
Thomas Kurz
Sybille Krauß

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1579194

1,034 views

Review

Accepted on 14 Jun 2025

Calcium Signaling in Postsynaptic Mitochondria: Mechanisms, Dynamics, and Role in ATP Production

in Molecular Signalling and Pathways

Tatiana Feofilaktova
Liliia Kushnireva
Menahem Segal
Eduard Korkotian

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1621070

178 views

Review

Published on 13 Jun 2025

Roles of ERK signaling pathway in regulating myelination of the peripheral nervous system

in Molecular Signalling and Pathways

Di Liu
Jingwei Zhou

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1617976

771 views