Frontiers in Molecular Neuroscience

Original Research

Published on 14 Oct 2025

PGC-1α promotes the survival of newborn neurons within AD hippocampus through activation of the FNDC5/BDNF/TrkB signaling pathway

Yi-Jie Wang
Yu-Xin Wang
Cheng-Zhi Zou
Wei-Jun Zhang
Wen Pan
Jia-Qing Wang
Hua Wang
Xin Qian
Guo-Jia-Hao Han
Feng-Guo Liu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1688694

427 views

Original Research

Published on 14 Oct 2025

Schizophrenia risk gene ZNF536 modulates retinoic acid response and neuronal gene networks in SH-SY5Y cells

Artemiy O. Kurishev
Dmitrii A. Abashkin
Dmitry S. Karpov
Ekaterina V. Marilovtseva
Yulia A. Chaika
Ekaterina V. Semina
Vera E. Golimbet

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1671354

465 views

Original Research

Accepted on 13 Oct 2025

Analyses of exon 4a structure reveal the properties of Big tau related to distribution, function and aggregation

Itzhak Fischer
Peter Baas

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1707820

Original Research

Accepted on 13 Oct 2025

Pex1 Loss-of-Function in Zebrafish Is Viable and Recapitulates Hallmarks of Zellweger Spectrum Disorders

Ursula Heins-Marroquin
Zlatan Hodzic
Beatriz Soares Carneiro da Silva
Agnes Hendriks
Floriane Gavotto
Marc O. Warmoes
Lisa Schlicker
Samy Omri
Christian Jäger
Enrico Glaab

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1634536

Brief Research Report

Accepted on 10 Oct 2025

Phosphoprofile reorganization of the actin binding protein Drebrin during long term depression

Rafaela Pedro Silva
Till G.A. Mack
Marieluise Kirchner
Philipp Mertins
Britta Johanna Eickholt
Patricia Kreis

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1697642

100 views

Mini Review

Published on 09 Oct 2025

Food for thought: probiotic modulation of microglial activity in Parkinson's disease

Isabella Kroker Kimber
Marie-Ève Tremblay

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1690507

1,047 views

Original Research

Published on 09 Oct 2025

Neuronal activity-dependent gene expression is stimulus-specific and changes with neuronal maturation

Jeronimo Lukin
Maximiliano S. Beckel
Olivia Pedroncini
Sebastian A. Giusti
Giuliana C. Di Mauro
Ivana Marcela Linenberg
Ines Lucia Patop
Ariel Chernomoretz
Antonia Marin-Burgin
Sebastian Kadener

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1609772

1,394 views

Original Research

Accepted on 08 Oct 2025

Regulation of Granin Neuropeptide Gene Expression in Human Brain during Development

Laura L Demsey
Sonia Podvin
Vivian Hook

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1666795

145 views

Review

Published on 08 Oct 2025

Peripheral–central immune interactions in Parkinson’s disease: insights into innate and adaptive immunity

Jarika Jahan Tumpa
Qurat Ul Ain Hayder
Nowshin Sharmily Maisa
Md. Nazmul Islam

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1682006

916 views

Original Research

Accepted on 07 Oct 2025

Transcriptomic profiling of neural cultures from the KYOU iPSC line via alternative differentiation protocols

Adelya Galiakberova
Sergey Ivanov
Nikolay Kondratyev
Arkadiy Golov
Alexander Artyuhov
Alexey Zolkin
Alexey A Lagunin
Vera Golimbet
Erdem Dashinimaev

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1661986

102 views

Systematic Review

Accepted on 07 Oct 2025

A Multi-Database Bibliometric and Translational Mapping of Microglial Mechanisms in Spinal Cord Pain Signaling

Lingji Zhou
Weiyu Pu
Shuxian Wang
Shihong Li
Song Cao

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1667201

126 views

Mini Review

Accepted on 06 Oct 2025

LYSINE α-KETOGLUTARATE REDUCTASE AS A THERAPEUTIC TARGET FOR SACCHAROPINE PATHWAY RELATED DISEASES

Gabriel Vieira Valderrama
Gabriela Alves Moreira
Paulo Arruda

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1695490

115 views

Original Research

Published on 03 Oct 2025

SIRT3 inhibits autophagy-dependent ferroptosis of HUVECs in the progression of pregnancy-induced hypertension by activating the PI3K/Akt/mTOR axis

Yanchuan Li
Yanfeng Liu
Ziyun Shi
Meiqing He

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1620184

831 views

Mini Review

Published on 03 Oct 2025

Neurochemical crossroads: exploring the neurotransmitter network in chronic pain and depression comorbidity

Min Ma
Yue Zhang
Kunming Tao
Zhijie Lu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1675814

948 views

Review

Accepted on 29 Sep 2025

Beyond Cell-Cell Contact: Therapeutic Potential of Eph Signaling in Central Nervous System Tumors

Fernanda Cristina Poscai Ribeiro
Moisés Willian Aparecido Gonçalves
Aleff Mascarenhas Silva
Tayná Figueiredo Maciel
Reydson Alcides De Lima-Souza
João Figueira Scarini
Gary Chris Fillmore
Erika Said Abu Egal

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1658651

233 views

Mini Review

Accepted on 29 Sep 2025

Proteostasis Disruption and Lipid Dyshomeostasis in Neurodegeneration: Exploring Common Druggable Targets Across Sporadic and Monogenic Disorders

Priscila Pereira Sena
Lea Friedrich
Alcibiades Elias Villarreal
Florian Fath
Liubovi Sopco
Mar Hernandez
Maria Luiza Saraiva-Pereira
Gabrielle Britton
Jonasz Jeremiasz Weber
Thorsten Schmidt

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1681079

243 views

4,285 Publications

Volume 18 - 2025

PGC-1α promotes the survival of newborn neurons within AD hippocampus through activation of the FNDC5/BDNF/TrkB signaling pathway

Schizophrenia risk gene ZNF536 modulates retinoic acid response and neuronal gene networks in SH-SY5Y cells

Analyses of exon 4a structure reveal the properties of Big tau related to distribution, function and aggregation

Pex1 Loss-of-Function in Zebrafish Is Viable and Recapitulates Hallmarks of Zellweger Spectrum Disorders

Phosphoprofile reorganization of the actin binding protein Drebrin during long term depression

Food for thought: probiotic modulation of microglial activity in Parkinson's disease

Neuronal activity-dependent gene expression is stimulus-specific and changes with neuronal maturation

Regulation of Granin Neuropeptide Gene Expression in Human Brain during Development

Peripheral–central immune interactions in Parkinson’s disease: insights into innate and adaptive immunity

Transcriptomic profiling of neural cultures from the KYOU iPSC line via alternative differentiation protocols

A Multi-Database Bibliometric and Translational Mapping of Microglial Mechanisms in Spinal Cord Pain Signaling

LYSINE α-KETOGLUTARATE REDUCTASE AS A THERAPEUTIC TARGET FOR SACCHAROPINE PATHWAY RELATED DISEASES

SIRT3 inhibits autophagy-dependent ferroptosis of HUVECs in the progression of pregnancy-induced hypertension by activating the PI3K/Akt/mTOR axis

Neurochemical crossroads: exploring the neurotransmitter network in chronic pain and depression comorbidity

Beyond Cell-Cell Contact: Therapeutic Potential of Eph Signaling in Central Nervous System Tumors

Proteostasis Disruption and Lipid Dyshomeostasis in Neurodegeneration: Exploring Common Druggable Targets Across Sporadic and Monogenic Disorders