Frontiers in Molecular Neuroscience

Original Research

Accepted on 29 Aug 2025

Cross-Disease Biomarker Identification Reveals Shared Diagnostic Biomarkers for IVDD and NAFLD via Bulk and Single-Cell RNA Sequencing

Jiasen Wei
Chenglong Ji
Lina Liu
Chen Yan
Jing-Chuan Sun
Wenbo Lin
Ximing Xu
Kaiqiang Sun

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1639705

Review

Published on 29 Aug 2025

IDH mutant high-grade gliomas

Santosh Valvi
Maryam Fouladi
Michael J. Fisher
Nicholas G. Gottardo

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1662414

364 views

Review

Published on 29 Aug 2025

Peroxisomes as emerging clinical targets in neuroinflammatory diseases

Andrej Roczkowsky
Richard A. Rachubinski
Tom C. Hobman
Christopher Power

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1642590

317 views

Editorial

Published on 29 Aug 2025

Editorial: Insights into molecular and cellular mechanisms of chronic pain and neuroinflammation

Silke Neumann
Amit Sharma
Jarek Maciaczyk

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1679721

377 views

Original Research

Accepted on 26 Aug 2025

Nfkbia-Driven Neuroinflammatory Pathways Mediate Depression Following Spinal Cord Injury

Aichun Yang
Guo-Yuan He
Yanling Song
Yujun Wen
Hechun Xia
Shenhong Gu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1596649

122 views

Original Research

Accepted on 25 Aug 2025

Divergent and Subnucleus-Specific Gene Expression Responses to Chronic Stress Hormone Exposure in the Amygdala

Shuhei Ueda
Manami Kakita
Masahito Hosokawa
Koji Arikawa
Kiyofumi Takahashi
Ryusuke Shiota
Masaki Kakeyama
Hiroko Matsunaga
Haruko Takeyama
Sayaka Takemoto-Kimura

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1659846

223 views

Correction

Accepted on 25 Aug 2025

S-9-PAHSA ameliorates cognitive decline in a Type 2 Diabetes mouse model by inhibiting oxidative stress and apoptosis via CAⅢ modulation

Xin-Ru Wang
Shan-Shan Huang
Meng Wang
Jin-Hong Lin
Jian-Tao Wang
Jiao-Qi Ren
Cheng-Feng He
Wen-Jiao Xue
Yin Wang
Xue-Chun Wang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1688881

291 views

Original Research

Accepted on 22 Aug 2025

Tamoxifen attenuates manganese-induced dysregulation of neuronal REST via the genomic ER-α mechanism

Alexis Digman
Edward Pajarillo
SANGHOON KIM
Itunu Ajayi
Deok-Soo Son
Michael Aschner
Eunsook Lee

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1648904

291 views

Original Research

Published on 22 Aug 2025

Organelle stresses and energetic metabolisms promote endothelial–to–mesenchymal transition and fibrosis via upregulating FOSB and MEOX1 in Alzheimer’s disease

Fatma Saaoud
Mohammed Ben Issa
Lu Liu
Keman Xu
Yifan Lu
Ying Shao
Baosheng Han
Xiaohua Jiang
Xiaolei Liu
Avrum Gillespie

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1605012

615 views

Correction

Published on 21 Aug 2025

Correction: Exosome-mediated miRNA delivery: a molecular switch for reshaping neuropathic pain therapy

Ziqing Wei
Chunhui Guo
Hang Zhou
Yanling Wu
Xudong Zhou
Jibing Chen
Fujun Li

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1668038

348 views

Original Research

Accepted on 20 Aug 2025

Neuroprotection Against Beta-Amyloid Toxicity By The Novel Estrogen Receptor Modulator STX Requires Convergent Signaling Pathways

Hun-Joo Lee
Zoe Bostick
John Doherty
Tracy L Swanson
Martin J Kelly
Joseph F Quinn
Nora E Gray
Philip F Copenhaver

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1670646

226 views

Original Research

Published on 18 Aug 2025

KCC2 inhibition and neuronal hyperexcitability promote extrinsic apoptosis dependent upon C1q

Jinglin Ji
Catherine Choi
Christopher E. Bope
Jacob S. Dengler
Stephen J. Moss
Joshua L. Smalley

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1645428

661 views

Editorial

Published on 14 Aug 2025

Editorial: Imaging brain network and brain energy metabolism impairments in brain disorders

Yuhei Takado
Mor Mishkovsky
Tomokazu Tsurugizawa

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1676946

429 views

Original Research

Published on 13 Aug 2025

ACTN2, regulated by PRDM9, affects the growth and inflammation of vascular smooth muscle cells by interacting with PDLIM1 in intracranial aneurysms

Guangxu Zhang
Jinbing Zhao
Zhiqiang Yu
Hongyi Liu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1606973

511 views

Original Research

Accepted on 11 Aug 2025

A comprehensive analysis of allele-specific expression and transcriptomic profiling in pig limbic and endocrine tissues

Muhammad Arsalan Iqbal
Frieder Hadlich
Henry Reyer
Michael Oster
Nares Trakooljul
Klaus Wimmers
Siriluck Ponsuksili

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1616363

200 views

Original Research

Published on 08 Aug 2025

Neuronal expression of S100B triggered by oligomeric Aβ peptide contributes to protection against cytoskeletal damage and synaptic loss

Joana Saavedra
Mariana Nascimento
António J. Figueira
Marina I. Oliveira da Silva
Tiago Gião
João Oliveira
Márcia A. Liz
Cláudio M. Gomes
Isabel Cardoso

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1636365

1,016 views

4,260 Publications

Volume 18 - 2025

Cross-Disease Biomarker Identification Reveals Shared Diagnostic Biomarkers for IVDD and NAFLD via Bulk and Single-Cell RNA Sequencing

IDH mutant high-grade gliomas

Peroxisomes as emerging clinical targets in neuroinflammatory diseases

Editorial: Insights into molecular and cellular mechanisms of chronic pain and neuroinflammation

Nfkbia-Driven Neuroinflammatory Pathways Mediate Depression Following Spinal Cord Injury

Divergent and Subnucleus-Specific Gene Expression Responses to Chronic Stress Hormone Exposure in the Amygdala

S-9-PAHSA ameliorates cognitive decline in a Type 2 Diabetes mouse model by inhibiting oxidative stress and apoptosis via CAⅢ modulation

Tamoxifen attenuates manganese-induced dysregulation of neuronal REST via the genomic ER-α mechanism

Organelle stresses and energetic metabolisms promote endothelial–to–mesenchymal transition and fibrosis via upregulating FOSB and MEOX1 in Alzheimer’s disease

Correction: Exosome-mediated miRNA delivery: a molecular switch for reshaping neuropathic pain therapy

Neuroprotection Against Beta-Amyloid Toxicity By The Novel Estrogen Receptor Modulator STX Requires Convergent Signaling Pathways

KCC2 inhibition and neuronal hyperexcitability promote extrinsic apoptosis dependent upon C1q

Editorial: Imaging brain network and brain energy metabolism impairments in brain disorders

ACTN2, regulated by PRDM9, affects the growth and inflammation of vascular smooth muscle cells by interacting with PDLIM1 in intracranial aneurysms

A comprehensive analysis of allele-specific expression and transcriptomic profiling in pig limbic and endocrine tissues

Neuronal expression of S100B triggered by oligomeric Aβ peptide contributes to protection against cytoskeletal damage and synaptic loss