CORRECTION article

Front. Neurol., 17 August 2022

Sec. Neuromuscular Disorders and Peripheral Neuropathies

Volume 13 - 2022 | https://doi.org/10.3389/fneur.2022.980597

Corrigendum: Clinical 3-D gait assessment of patients with polyneuropathy associated with hereditary transthyretin amyloidosis

  • 1. INESC TEC, FEUP and LABIOMEP, University of Porto, Porto, Portugal

  • 2. Unidade Corino de Andrade and Neurophysiology Department, Centro Hospitalar Universitário Do Porto, Porto, Portugal

  • 3. Institute of Electronics and Informatics Engineering of Aveiro (IEETA), Department of Electronics, Telecommunications and Informatics, University of Aveiro, Aveiro, Portugal

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In the published article, there was an error in Table 2 as published. The units of the Total body center of mass sway in x-axis (TBCMx) and y-axis (TBCMy) were shown in mm when they should be in cm. The corrected Table 2 and its caption appear below.

Table 2

Gait parameter 1. HC 2. AC 3. SP 3.1 SPS 3.2 SPSL 3.3 SMP
Stride duration, s 1.238 ± 0.386 1.463 ± 0.518 1.628 ± 0.690 1.709 ± 0.729 1.463 ± 0.509 1.616 ± 0.768
Stride length, cm 114.7 ± 23.0 101.5 ± 28.0 93.6 ± 25.5 92.8 ± 25.6 91.7 ± 23.7 100.2 ± 27.3
Step duration, s 0.626 ± 0.282 0.732 ± 0.343 0.823 ± 0.489 0.862 ± 0.517 0.744 ± 0.396 0.816 ± 0.513
Step length, cm 52.2 ± 13.5 47.3 ± 15.5 42.6 ± 15.6 42.6 ± 15.9 41.6 ± 15.3 44.7 ± 14.4
Step width, cm 12.4 ± 3.7 12.1 ± 3.8 13.0 ± 4.2 13.7 ± 4.4 12.1 ± 4.1 12.2 ± 3.2
Stance duration, s 0.784 ± 0.261 0.943 ± 0.396 1.012 ± 0.525 1.057 ± 0.559 0.901 ± 0.360 1.044 ± 0.608
Swing duration, s 0.455 ± 0.245 0.521 ± 0.301 0.616 ± 0.414 0.652 ± 0.451 0.562 ± 0.342 0.573 ± 0.367
Single support duration, s 0.897 ± 0.331 1.043 ± 0.451 1.219 ± 0.575 1.292 ± 0.623 1.104 ± 0.440 1.142 ± 0.559
Double support duration, s 0.341 ± 0.125 0.421 ± 0.172 0.409 ± 0.267 0.417 ± 0.296 0.359 ± 0.139 0.474 ± 0.309
Gait speed, m/s 1.047 ± 0.239 0.846 ± 0.228 0.728 ± 0.180 0.696 ± 0.161 0.767 ± 0.182 0.785 ± 0.218
Gait speed variability, m/s 0.105 ± 0.057 0.153 ± 0.384 0.121 ± 0.216 0.107 ± 0.119 0.125 ± 0.208 0.170 ± 0.423
Foot swing velocity, m/s 2.679 ± 1.031 2.318 ± 1.334 1.894 ± 1.109 1.807 ± 1.103 1.917 ± 0.917 2.195 ± 1.376
Arm swing velocity, m/s 1.976 ± 0.749 1.570 ± 0.798 1.384 ± 0.709 1.312 ± 0.515 1.405 ± 0.575 1.633 ± 1.299
Total body center of mass sway in x-axis, cm 29.2 ± 38.7 35.5 ± 26.1 34.1 ± 37.9 29.7 ± 33.1 44.7 ± 41.5 31.5 ± 44.2
Total body center of mass sway in y-axis, cm 10.2 ± 5.4 13.7 ± 15.5 11.1 ± 8.4 10.9 ± 7.5 11.6 ± 10.7 10.9 ± 7.0
Neck angle, deg 166.1 ± 10.2 162.3 ± 14.2 158.1 ± 17.7 160.4 ± 13.8 152.1 ± 23.5 160.2 ± 16.5
Spine shoulder angle, deg 171.3 ± 5.8 168.5 ± 8.7 165.7 ± 11.3 167.1 ± 8.9 161.9 ± 15.3 167.2 ± 9.4
Spine middle angle, deg 175.9 ± 2.2 174.7 ± 2.7 173.6 ± 3.3 173.8 ± 3.2 172.8 ± 3.6 173.9 ± 3.3
Maximum elbow angle, deg 167.6 ± 10.9 166.0 ± 9.7 166.0 ± 10.1 166.1 ± 9.3 166.5 ± 12.8 164.5 ± 6.2
Minimum elbow angle, deg 144.3 ± 20.4 144.7 ± 20.4 144.8 ± 21.8 145.3 ± 20.1 144.7 ± 26.0 142.6 ± 19.9
Maximum knee angle, deg 174.5 ± 3.1 176.8 ± 2.5 174.8 ± 3.5 174.5 ± 3.6 174.8 ± 3.4 176.1 ± 3.1
Minimum knee angle, deg 142.0 ± 17.7 142.5 ± 17.1 143.1 ± 18.4 142.6 ± 18.1 145.3 ± 17.7 141.1 ± 20.8
Hip angle range, deg 19.3 ± 7.0 18.9 ± 7.5 17.1 ± 6.8 17.3 ± 7.2 16.0 ± 5.8 18.4 ± 7.1
Ankle angle range, deg 33.6 ± 16.6 27.9 ± 17.6 20.7 ± 16.0 17.6 ± 14.2 22.0 ± 16.0 30.3 ± 18.4

Mean ± standard deviation values for each gait parameter and each subject group (1. Healthy Controls – HC; 2. Asymptomatic Carriers – AC; 3. Symptomatic Patients – SP; 3.1 Patients with small-fiber sensory polyneuropathy – SPS – and 3.2 with large-fiber sensory polyneuropathy – SPSL; and 3.3 Patients with motor neuropathy – SMP).

In the published article, there was an error in Table 3 as published. The units of the Total body center of mass sway in x-axis (TBCMx) and y-axis (TBCMy) were shown in mm. The correct unit is cm. The corrected Table 3 and its caption appear below.

Table 3

Gait parameter HC–AC HC–SP AC–SP AC–SPS SPS–SPSL SPSL–SMP HC–SMP
Stride duration, s ≤ 0.001 ≤ 0.001 ≤ 0.001 ≤ 0.001 ≤ 0.001 ≤ 0.001 ≤ 0.001
Stride length, cm 0.04
Step duration, s ≤ 0.001
Step length, cm
Step width, cm N.S. N.S. N.S.
Stance duration, s ≤ 0.001 ≤ 0.001 ≤ 0.001
Swing duration, s N.S.
Single support duration, s
Double support duration, s ≤ 0.001
Gait speed, m/s N.S.
Gait speed variability, m/s N.S. ≤ 0.001
Foot swing velocity, m/s ≤ 0.001 0.002
Arm swing velocity, m/s ≤ 0.001
Total body center of mass sway in x-axis (TBCMx), cm 0.036
Total body center of mass sway in y-axis (TBCMy), cm N.S. N.S. N.S.
Neck angle, deg ≤ 0.001 ≤ 0.001 ≤ 0.001
Spine shoulder angle, deg
Spine middle angle, deg
Maximum elbow angle, deg N.S. N.S.
Minimum elbow angle, deg N.S. 0.009 0.038 0.003 N.S.
Maximum knee angle, deg ≤ 0.001 ≤ 0.001 ≤ 0.001 0.046 ≤ 0.001
Minimum knee angle, deg 0.007 N.S. N.S. 0.002 0.022 N.S.
Hip angle range, deg ≤ 0.001 ≤ 0.001 ≤ 0.001 ≤ 0.001 ≤ 0.001 ≤ 0.001
Ankle angle range, deg

Results of the Conover-Iman test (p-value) pairwise comparison between the six groups included in Table 2 (HC, AC, SP, SPS, SPSL and SMP), for each gait parameter.

N.S. stands for non-significant (p-value > 0.05).

In the published article, there was an error in Figure 3 as published. The units of the Total body center of mass sway in x-axis were shown in mm in the vertical axis of the plot. The correct unit is cm. The corrected Figure 3 and its caption appear below.

Figure 3

Figure 3

Mean and standard deviation for each subject group, for the gait parameters that showed statistically significant differences in the Conover-Iman test (p ≤ 0.05) for all the comparisons, when comparing different pairwise comparison, included in Table III, between the six groups (HC, AC, SP, SPS, SPSL and SMP).

In the published article, there was an error in Supplementary Table S.I. The units of the Total body center of mass sway in x-axis (TBCMx) and y-axis (TBCMy) were shown in mm. The correct unit is cm. The correct material statement appears below.

Table S.I

Gait parameter HC-SPS HC–SPSL AC–SPSL AC–SMP SPS–SMP
Stride duration, s ≤ 0.001 ≤ 0.001 N.S. ≤ 0.001 ≤ 0.001
Stride length, cm ≤ 0.001 0.003
Step duration, s N.S. ≤ 0.001 0.005
Step length, cm ≤ 0.001 N.S.
Step width, cm N.S. 0.035 N.S. ≤ 0.001
Stance duration, s ≤ 0.001 ≤ 0.001 ≤ 0.001 N.S.
Swing duration, s ≤ 0.001
Single support duration, s
Double support duration, s N.S.
Gait speed, m/s ≤ 0.001
Gait speed variability, m/s N.S. 0.009 N.S.
Foot swing velocity, m/s ≤ 0.001 ≤ 0.001 0.021
Arm swing velocity, m/s N.S.
Total body center of mass sway in x-axis (TBCMx), cm 0.015 ≤ 0.001
Total body center of mass sway in y-axis (TBCMy), cm ≤ 0.001 N.S. 0.023
Neck angle, deg N.S. ≤ 0.001
Spine shoulder angle, deg 0.03 N.S.
Spine middle angle, deg 0.003
Maximum elbow angle, deg N.S. ≤ 0.001
Minimum elbow angle, deg ≤ 0.001 0.021 ≤ 0.001
Maximum knee angle, deg 0.037 ≤ 0.001
Minimum knee angle, deg 0.004 N.S.
Hip angle range, deg ≤ 0.001 N.S.
Ankle angle range, deg 0.025 0.01

Results of the Conover-Iman test (p-value) for the pairwise comparisons not presented in Table 3 between the six considered groups (HC, AC, SP, SPS, SPSL and SMP), for each gait parameter.

N.S. stands for non-significant (p-value > 0.05).

In the published article, there was a mistake on the computation description of one of the assessed parameters (total body center of mass). A correction has been made to “Data Processing,” Paragraph 3:

“For each gait cycle, we computed the 24 spatiotemporal and kinematic gait parameters listed in Table 2 and defined in (15). The total body center of mass (TBCM) sway was computed as the standard deviation of the distance (in the x/y-axis, i.e., medial-lateral and vertical directions) of the total body center of mass (TBCM), in relation to the RGB-D sensor's coordinate system, for all gait cycle frames. For each frame, TBCM's position is the mean position of all body segments' CM, which was obtained according to (21).”

The authors apologize for these errors and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Publisher's note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Summary

Keywords

ATTRv V30M, amyloidosis, polyneuropathy, gait, quantitative assessment, ambulatory, markerless vision-based systems

Citation

Vilas-Boas MdC, Rocha AP, Cardoso MN, Fernandes JM, Coelho T and Cunha JPS (2022) Corrigendum: Clinical 3-D gait assessment of patients with polyneuropathy associated with hereditary transthyretin amyloidosis. Front. Neurol. 13:980597. doi: 10.3389/fneur.2022.980597

Received

28 June 2022

Accepted

19 July 2022

Published

17 August 2022

Volume

13 - 2022

Edited by

Chiara Briani, University of Padua, Italy

Reviewed by

Valeria Prada, University of Genoa, Italy; Daniele Coraci, University of Padua, Italy

Updates

Copyright

*Correspondence: João Paulo Silva Cunha

This article was submitted to Neuromuscular Disorders and Peripheral Neuropathies, a section of the journal Frontiers in Neurology

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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