ORIGINAL RESEARCH article
Front. Neurol.
Sec. Epilepsy
Volume 16 - 2025 | doi: 10.3389/fneur.2025.1555586
Construction of Epilepsy Diagnosis Model Based on Cell Senescencerelated Genes and its Potential Mechanism
Provisionally accepted
- 1The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China
- 2Suqian Hospital Affiliated to Xuzhou Medical University, Suqian, Jiangsu Province, China
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The article examines the role of cellular senescence in epilepsy, highlighting its significant impact on human physiology and diseases, and emphasizing the potential importance of this less-explored area.2. Methodology: The study analyzes differentially expressed genes from the GEO database, cross-referencing them with cellular senescence-related genes to reveal correlations with clinical phenotypes through data analysis.3. Bioinformatics Analysis: Utilizing GO, KEGG, and GSEA methods, the study investigates the functional enrichment and biological process differences of cellular senescence-related genes in epilepsy, clarifying their biological roles.
Keywords: Data curation, methodology, Writing -review & editing. Xiangyao Gong: Data curation, investigation, Writingoriginal draft. Qihua Xiao: Project administration, supervision, Writing -review & editing. Wei Lu: Data curation, Formal analysis
Received: 05 Jan 2025; Accepted: 13 May 2025.
Copyright: © 2025 Gong, Lu, Xiao, Wang, Chenchen and Tang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Hai Tang, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China
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