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SYSTEMATIC REVIEW article

Front. Neurol.

Sec. Neuroepidemiology

This article is part of the Research TopicLeveraging Big Data Mining to Advance Neurological ResearchView all 8 articles

Effect of Traditional Chinese Exercises on Motor Function, Balance, Gait, and Quality of Life in Patients with Parkinson's Disease: A Systematic Review and Meta-analysis

Provisionally accepted
Yapei  SongYapei Song1Liang  LiLiang Li2tonggang  fantonggang fan2xiaoyan  huangxiaoyan huang3ChunAI  zhaoChunAI zhao1*
  • 1Shanghai Institute of Tourism, Shanghai Normal University, Shanghai, China
  • 2Shanghai University of Sport, Shanghai, China
  • 3Shanghai Research Institute of Sports Science, Shanghai, China

The final, formatted version of the article will be published soon.

Traditional Chinese exercises (TCEs), recognised as a mind-body, non-pharmacological therapy, are frequently incorporated into the clinical management of PD. Despite their widespread use, the optimal therapeutic effects and ideal exercise prescriptions for TCEs remain uncertain. Therefore, we aimed to comprehensively evaluate the impact of TCEs on motor function, balance, gait, and quality of life in patients with PD through a systematic review and meta-analysis, with the goal of providing evidence-based guidance for the selection of the most suitable exercise regimen. Methods: This study adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, utilising the PICOS framework to systematically search seven databases—CNKI, Wanfang, VIP, PubMed, Embase, Cochrane Library, and Web of Science—for randomised controlled trials (RCTs) published from their inception up to October 2025. Two independent authors screened all eligible studies, and study quality and risk of bias were assessed using the criteria outlined in the Cochrane Handbook version 5.1. Extracted data were statistically analysed using RevMan 5.4 software, calculating the mean difference (MD) or standardised mean difference (SMD) with 95% confidence intervals (CIs) and evaluating heterogeneity (I2) among the studies. Results: Thirteen RCTs involving 859 patients were ultimately included in the analysis1. The meta-analysis results showed that, compared with the usual control group, TCEs significantly improved patients’ motor function (Unified Parkinson’s Disease Rating Scale part III, UPDRS-III, MD: -4.30, 95% CI: -5.90 to -2.70, P < 0.00001, I2=71%) and balance function (Berg Balance Scale, MD: 2.63, 95% CI: 1.30–3.96, P = 0.0001, I2=0%; Timed Up and Go Test, TUGT, MD: -1.19, 95% CI: -2.03 to -0.35, P = 0.005,I2=65). However, the improvements observed in gait function (stride length, P = 0.07; cadence, P = 0.85; and gait velocity, P = 0.77) and quality of life (PDQ-39, P = 0.11) were not statistically significant. Conclusion: Based on these findings, we recommend Qigong as the preferred modality for early- and moderate-stage PD patients, with an optimal initial prescription involving a duration of ≤12 weeks, a frequency of > 3 times per week, and the independent practice of TCEs.

Keywords: Traditional Chinese exercises, Parkinson's disease, Motor function, balance, Gait, Quality of Life, Meta-analysis

Received: 18 Sep 2025; Accepted: 17 Dec 2025.

Copyright: © 2025 Song, Li, fan, huang and zhao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: ChunAI zhao

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