Your new experience awaits. Try the new design now and help us make it even better

ORIGINAL RESEARCH article

Front. Neurol.

Sec. Endovascular and Interventional Neurology

This article is part of the Research TopicChronic Large-Vessel Occlusion in Cerebrovascular Disease: Pathophysiology, Diagnosis, and Therapeutic AdvancesView all 3 articles

The value of ultrasound in transradial access cerebral angiography

Provisionally accepted
Zhen  SunZhen Sun1,2,3Wenyue  WeiWenyue Wei1Hui  ZhangHui Zhang1Congcong  JiaCongcong Jia1Chen  ZhouChen Zhou1Gang  LuoGang Luo4,5Wanying  LiWanying Li1Shuming  GuoShuming Guo1*
  • 1Linfen Central Hospital, Linfen, China
  • 2Tianjin Medical University, Tianjin, China
  • 3Tianjin Huanhu Hospital, Tianjin, China
  • 4Capital Medical University, Beijing, China
  • 5Beijing Tiantan Hospital Department of Interventional Neuroradiology, Beijing, China

The final, formatted version of the article will be published soon.

Background: Transradial access (TRA) for cerebral angiography presents challenges such as puncture failures, prolonged procedure times, and difficulties in catheter advancement due to radial artery variations. Utilizing ultrasound guidance, which has demonstrated success in coronary angiography, may improve TRA outcomes. This study aimed to assess the efficacy of ultrasound-guided TRA in cerebral angiography, focusing on success rates, procedure duration, and patient satisfaction. Method: A prospective, non-randomized, controlled trial included 197 patients scheduled for TRA between June 2022 and January 2024. Patients undergoing cerebral angiography through TRA were divided into control and ultrasound group. The ultrasound group underwent preoperative right upper extremity artery ultrasound assessment, with ultrasound-guided puncture for challenging cases. The primary outcomes were procedure completion rate, duration, patient satisfaction, and complication rates. Statistical analyses were performed using Student's t-test for continuous variables and the chi-square test for categorical variables to compare these outcomes between the two groups, using a two-tailed significance level of p < 0.05. Results: This study included a total of 197 patients: 73 in the control group and 124 in the ultrasound group. TRA was completed in 69 patients (94.5%) in the control group and 117 patients (99.2%) in This is a provisional file, not the final typeset article the ultrasound group. The average operation time was 0.67 ± 0.19 hours in the control group and 0.55 ± 0.19 hours in the ultrasound group (p <0.001). Difficult access occurred in 15 patients (21.7%) in the control group compared with 2 patients (1.7%) in the ultrasound group (p <0.001). No significant differences were observed in either complication rates or patient satisfaction: 8 patients (11.6%) in the control group and 9 (7.7%) in the ultrasound group (p = 0.372) had complications, while 57 patients (82.6%) in the control group and 109 (93.2%) in the ultrasound group reported satisfaction (p = 0.089). Conclusion: Ultrasound-guided TRA in cerebral angiography effectively mitigated challenges related to puncture failures and procedure duration, offering the potential to improve outcomes and patient satisfaction in TRA procedures.

Keywords: ultrasound, Transradial access, Cerebral Angiography, radial artery variations, complication

Received: 29 Sep 2025; Accepted: 17 Nov 2025.

Copyright: © 2025 Sun, Wei, Zhang, Jia, Zhou, Luo, Li and Guo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Shuming Guo, eguoshuming_1970@163.com

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.