ORIGINAL RESEARCH article
Front. Neurol.
Sec. Artificial Intelligence in Neurology
A Neutrosophic Explainable AI Framework for Modeling Uncertainty in Immersive Stereotactic Neurosurgical Simulation
Provisionally accepted- Universidad Tecnológica Ecotec, Guayaquil, Ecuador
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The integration of Artificial Intelligence (AI) and Virtual Reality (VR) has transformed medical education; however, performance assessment in high-stakes fields such as stereotactic neurosurgery remains largely dependent on binary or threshold-based metrics. In procedures such as Deep Brain Stimulation (DBS), where safety margins are below 2 mm, these approaches fail to capture indeterminate behaviors, including hesitation, micro-instability, and unstable trajectories, potentially leading to false-positive competence classifications. This study introduces a Neutrosophic Explainable AI (N-XAI) framework that models surgical performance through three independent dimensions: Truth (competence), Indeterminacy (instability/ambiguity), and Falsity (error). Performance is represented in a two-dimensional precision–stability space and quantified using single-valued neutrosophic sets. For theoretical validation, a synthetic dataset comprising 60 simulated surgical attempts distributed across three skill groups (expert, indeterminate, novice) was generated. Neutrosophic competence scores were computed and analyzed using non-parametric statistical tests. The framework successfully differentiated the three groups and identified indeterminate, high-risk cases that achieved acceptable spatial accuracy but exhibited significant instability—patterns that conventional metrics fail to detect. The proposed N-XAI framework provides a mathematically grounded and interpretable approach for modeling uncertainty in immersive neurosurgical simulation. By explicitly accounting for This is a provisional file, not the final typeset article indeterminacy, it enhances the diagnostic value of VR-based training systems and lays the groundwork for future validation in live stereotactic simulation environments.
Keywords: Deep brainstimulation, Explainable AI, Neutrosophic logic, Stereotactic Neurosurgery, uncertainty modeling
Received: 19 Dec 2025; Accepted: 31 Jan 2026.
Copyright: © 2026 Hechavarria-Hernandez. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Jesus Rafael Hechavarria-Hernandez
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